Alina Constantinescu

2025

The tacrolimus concentration-to-dose ratio is associated with kidney function in heart transplant recipients

Schagen, M. R., Petersen, T. B., Seijkens, B. C. A., Brugts, J. J., Caliskan, K., Constantinescu, A. A., de Winter, B. C. M., Kardys, I., Hesselink, D. A. & Manintveld, O., 19 Mar 2025, In: British Journal of Clinical Pharmacology. 15 p.

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Early Postoperative Changes in Von Willebrand Factor Activity Are Associated With Future Bleeding and Stroke in HeartMate 3 Patients

Jahangiri, P., Veen, K. M., van Moort, I., Bunge, J. H., Constantinescu, A., Sjatskig, J., de Maat, M., Kluin, J., Leebeek, F. & Caliskan, K., 1 Jan 2025, In: ASAIO journal (American Society for Artificial Internal Organs : 1992). 71, 1, p. 27-35 9 p.

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1 Citation (Scopus)

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2024

Temporal evolution of anxiety and depression in chronic heart failure and its association with clinical outcome

Abou Kamar, S., Oostdijk, B., Andrzejczyk, K., Constantinescu, A., Caliskan, K., Akkerhuis, K. M., Umans, V., Brugts, J. J., Boersma, E., van Dalen, B. & Kardys, I., 15 Sept 2024, In: International Journal of Cardiology. 411, 132274.

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3 Citations (Scopus)

15 Downloads (Pure)

Proteomic biomarkers related to obesity in heart failure with reduced ejection fraction and their associations with outcome

Petersen, T. B., Suthahar, N., Asselbergs, F. W., de Bakker, M., Akkerhuis, K. M., Constantinescu, A. A., van Ramshorst, J., Katsikis, P. D., van der Spek, P. J., Umans, V. A., de Boer, R. A., Boersma, E., Rizopoulos, D. & Kardys, I., Sept 2024, In: Obesity. 32, 9, p. 1658-1669 12 p.

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Temporal changes in CT-derived fractional flow reserve in patients after heart transplantation

Sharma, S., Sanz, J., Hirsch, A., Patel, R., Constantinescu, A., Barghash, M., Mancini, D., Brugts, J., Caliskan, K., Taverne, Y., Manintveld, O. & Budde, R., 17 Jul 2024, In: European Radiology. 35, 1, p. 232-243 12 p., e14167.

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1 Citation (Scopus)

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Temporal evolution of liver function parameters predicts clinical outcome in chronic heart failure patients (Bio-SHiFT study)

Klimczak-Tomaniak, D., Andrzejczyk, K., Kamar, S. A., Baart, S., Boven, N. V., Akkerhuis, K. M., Constantinescu, A., Caliskan, K., Simsek, S., Germans, T., Ramshorst, J. V., Brugts, J., Kuch, M., Umans, V., Boersma, E. & Kardys, I., 2024, In: Cardiology Journal. 31, 3, p. 409-417 9 p.

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2023

Pectus Excavatum and Risk of Right Ventricular Failure in Left Ventricular Assist Device Patients

Zijderhand, C. F., Yalcin, Y. C., Sjatskig, J., Bos, D., Constantinescu, A. A., Manintveld, O. C., Birim, O., Bekkers, J. A., Bogers, A. J. J. C. & Caliskan, K., 9 Nov 2023, In: Reviews in Cardiovascular Medicine. 24, 11, 313.

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1 Citation (Scopus)

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Long-Term Outcome of ICD Therapy in Patients With Noncompaction Cardiomyopathy Compared With DCM and HCM

Kaya, E., Otten, M., Theuns, D. A. M. J., Veen, K., Yap, S.-C., Schinkel, A. F. L., Constantinescu, A. A., Michels, M., Manintveld, O. C., Szili-Torok, T. & Caliskan, K., Aug 2023, In: JACC: Clinical Electrophysiology. 9, 8, p. 1368-1378 11 p.

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Potential role of left atrial strain in estimation of left atrial pressure in patients with chronic heart failure

Aga, Y. S., Abou Kamar, S., Chin, J. F., van den Berg, V. J., Strachinaru, M., Bowen, D., Frowijn, R., Akkerhuis, M. K., Constantinescu, A. A., Umans, V., Geleijnse, M. L., Boersma, E., Brugts, J. J., Kardys, I. & van Dalen, B. M., Aug 2023, In: ESC heart failure. 10, 4, p. 2345-2353 9 p.

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8 Citations (Scopus)

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Proteomic biomarkers related to obesity in heart failure patients and their associations with mortality

Petersen, T. B., Suthahar, N., Asselbergs, F. W., De Bakker, M., Akkerhuis, K. M., Constantinescu, A. A., Van Ramshorst, J., Katsikis, P. D., Van Der Spek, P. J., Umans, V. A., De Boer, R. A., Boersma, E., Rizopoulos, D. & Kardys, I., Jul 2023, In: European Journal of Heart Failure. 25, p. 396-397 2 p.

Research output: Contribution to journal › Meeting Abstract › Academic

The clinical impact of tricuspid regurgitation in patients with a biatrial orthotopic heart transplant

Veen, K. M., Papageorgiou, G., Zijderhand, C. F., Mokhles, M. M., Brugts, J. J., Manintveld, O. C., Constantinescu, A. A., Bekkers, J. A., Takkenberg, J. J. M., Bogers, A. J. J. C. & Caliskan, K., Jun 2023, In: Frontiers of Medicine. 17, 3, p. 527-533 7 p.

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2 Citations (Scopus)

Mechanical Device Malfunction of the HeartMate II Versus the HeartMate 3 Left Ventricular Assist Device: The Rotterdam Experience

Van Der Heiden, C. W., Zijderhand, C. F., Veen, K. M., Constantinescu, A. A., Manintveld, O. C., Brugts, J. J., Bekkers, J. A., Birim, O., Bogers, A. J. J. C. & Caliskan, K., 1 Feb 2023, In: ASAIO Journal. 69, 2, p. E80-E85

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4 Citations (Scopus)

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The Dutch national paediatric heart transplantation programme: outcomes during a 23-year period

Roest, S., van der Meulen, M. H., van Osch-Gevers, L. M., Kraemer, U. S., Constantinescu, A. A., de Hoog, M., Bogers, A. J. J. C., Manintveld, O. C., van de Woestijne, P. C. & Dalinghaus, M., Feb 2023, In: Netherlands Heart Journal. 31, 2, p. 68-75 8 p.

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1 Citation (Scopus)

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2022

Heart failure subphenotypes based on repeated biomarker measurements are associated with clinical characteristics and adverse events (Bio-SHiFT study)

de Lange, I., Petersen, T. B., de Bakker, M., Akkerhuis, K. M., Brugts, J. J., Caliskan, K., Manintveld, O. C., Constantinescu, A. A., Germans, T., van Ramshorst, J., Umans, V. A. W. M., Boersma, E., Rizopoulos, D. & Kardys, I., 1 Oct 2022, In: International Journal of Cardiology. 364, p. 77-84 8 p.

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4 Citations (Scopus)

105 Downloads (Pure)

Relapsing low-flow alarms due to suboptimal alignment of the left ventricular assist device inflow cannula

Zijderhand, C. F., Knol, W. G., Budde, R. P. J., van der Heiden, C. W., Veen, K. M., Sjatskig, J., Manintveld, O. C., Constantinescu, A. A., Birim, O., Bekkers, J. A., Bogers, A. J. J. C. & Caliskan, K., 1 Oct 2022, In: European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery. 62, 4, ezac415.

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3 Citations (Scopus)

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Prevalence of Iron Deficiency and Iron Administration in Left Ventricular Assist Device and Heart Transplantation Patients

Veenis, J. F., Radhoe, S. P., Roest, S., Caliskan, K., Constantinescu, A. A., Manintveld, O. C. & Brugts, J. J., Jul 2022, In: ASAIO Journal. 68, 7, p. 899-906 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

5 Citations (Scopus)

Theophylline Use to Prevent Permanent Pacing in the Contemporary Era of Heart Transplantation: The Rotterdam Experience

Kooij, C., Szili-Torok, T., Roest, S., Constantinescu, A. A., Brugts, J. J., Manintveld, O. & Caliskan, K., 24 Jun 2022, In: Frontiers in Cardiovascular Medicine. 9, 896141.

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7 Citations (Scopus)

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Single-Center Experience With Protocolized Treatment of Left Ventricular Assist Device Infections

Verkaik, N. J., Yalcin, Y. C., Bax, H. I., Constantinescu, A. A., Brugts, J. J., Manintveld, O. C., Birim, O., Croughs, P. D., Bogers, A. J. J. C. & Caliskan, K., 24 May 2022, In: Frontiers in Medicine. 9, 6 p., 835765.

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2 Citations (Web of Science)

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Oral Glucose Tolerance Test for the Screening of Glucose Intolerance Long Term Post‐Heart Transplantation

Roest, S., Goedendorp-Sluimer, M. M., Köbben, J. J., Constantinescu, A. A., Taverne, Y. J. H. J., Zijlstra, F., Zandbergen, A. A. M. & Manintveld, O. C., 19 Apr 2022, In: Transplant International. 35, 10113.

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1 Citation (Scopus)

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Cardiac allograft vasculopathy and donor age affecting permanent pacemaker implantation after heart transplantation

Roest, S., Manintveld, O. C., Kolff, M. A. E., Akca, F., Veenis, J. F., Constantinescu, A. A., Brugts, J. J., Birim, O., van Osch-Gevers, L. M., Szili-Torok, T. & Caliskan, K., Apr 2022, In: ESC heart failure. 9, 2, p. 1239-1247 9 p.

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7 Citations (Scopus)

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CT-derived fractional flow reserve (FFRct) for functional coronary artery evaluation in the follow-up of patients after heart transplantation

Budde, R. P. J., Nous, F. M. A., Roest, S., Constantinescu, A. A., Nieman, K., Brugts, J. J., Koweek, L. M., Hirsch, A., Leipsic, J. & Manintveld, O. C., Mar 2022, In: European Radiology. 32, 3, p. 1843-1852 10 p.

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10 Citations (Scopus)

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Endovascular renal sympathetic denervation to improve heart failure with reduced ejection fraction: the IMPROVE-HF-I study

Feyz, L., Nannan Panday, R., Henneman, M., Verzijlbergen, F., Constantinescu, A. A., van Dalen, B. M., Brugts, J. J., Caliskan, K., Geleijnse, M. L., Kardys, I., Van Mieghem, N. M., Manintveld, O. & Daemen, J., Mar 2022, In: Netherlands Heart Journal. 30, 3, p. 149-159 11 p.

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12 Citations (Scopus)

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Dynamic personalized risk prediction in chronic heart failure patients: a longitudinal, clinical investigation of 92 biomarkers (Bio-SHiFT study)

Klimczak-Tomaniak, D., de Bakker, M., Bouwens, E., Akkerhuis, K. M., Baart, S., Rizopoulos, D., Mouthaan, H., van Ramshorst, J., Germans, T., Constantinescu, A., Manintveld, O., Umans, V., Boersma, E. & Kardys, I., 18 Feb 2022, In: Scientific Reports. 12, 1, 2795.

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17 Citations (Scopus)

26 Downloads (Pure)

2021

Evaluation of patients with a HeartMate 3 left ventricular assist device using echocardiographic particle image velocimetry

Schinkel, A. F. L., Akin, S., Strachinaru, M., Muslem, R., Bowen, D., Yalcin, Y. C., Brugts, J. J., Constantinescu, A. A., Manintveld, O. C. & Caliskan, K., Dec 2021, In: Journal of Ultrasound. 24, 4, p. 499-503 5 p.

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4 Citations (Scopus)

15 Downloads (Pure)

Listing criteria for heart transplantation in the Netherlands

de Jonge, N., Damman, K., Ramjankhan, F. Z., van der Kaaij, N. P., van den Broek, S. A. J., Erasmus, M. E., Kuijpers, M., Manintveld, O., Bekkers, J. A., Constantinescu, A. C., Brugts, J. J., Oerlemans, M. I. F., van Laake, L. W. & Caliskan, K., Dec 2021, In: Netherlands Heart Journal. 29, 12, p. 611-622 12 p.

Research output: Contribution to journal › Review article › Academic › peer-review

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5 Citations (Scopus)

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Clinical implementation of coronary computed tomography angiography for routine detection of cardiac allograft vasculopathy in heart transplant patients

Nous, F. M. A., Roest, S., van Dijkman, E. D., Attrach, M., Caliskan, K., Brugts, J. J., Nieman, K., Hirsch, A., Constantinescu, A. A., Manintveld, O. C. & Budde, R. P. J., Oct 2021, In: Transplant International. 34, 10, p. 1886-1894 9 p.

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16 Citations (Scopus)

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Preventive implantable cardioverter defibrillator therapy in contemporary clinical practice: need for more stringent selection criteria

Deckers, J. W., Arshi, B., van den Berge, J. C. & Constantinescu, A. A., Oct 2021, In: ESC heart failure. 8, 5, p. 3656-3662 7 p.

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3 Citations (Scopus)

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Personalized screening intervals for measurement of N-terminal pro-B-type natriuretic peptide improve efficiency of prognostication in patients with chronic heart failure

Schuurman, A. S., Tomer, A., Akkerhuis, K. M., Brugts, J. J., Constantinescu, A. A., Ramshorst, J. V., Umans, V. A., Boersma, E., Rizopoulos, D. & Kardys, I., 1 Sept 2021, In: European Journal of Preventive Cardiology. 28, 9, p. E11-E14

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6 Citations (Scopus)

Safety of Endomyocardial Biopsy in New-Onset Acute Heart Failure Requiring Veno-Arterial Extracorporeal Membrane Oxygenation

Van Der Boon, R. M. A., Den Dekker, W. K., Meuwese, C. L., Lorusso, R., Von Der Thüsen, J. H., Constantinescu, A. C., Manintveld, O. C., Delnoij, T. S. R., Van Der Heijden, J. J., Van Mieghem, N. M. D. A. & Den Uil, C. A., Aug 2021, In: Circulation: Heart Failure. 14, 8, e008387.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

17 Citations (Scopus)

Sex-specific temporal evolution of circulating biomarkers in patients with chronic heart failure with reduced ejection fraction

Schreuder, M. M., Schuurman, A., Akkerhuis, K. M., Constantinescu, A. A., Caliskan, K., van Ramshorst, J., Germans, T., Umans, V. A., Boersma, E., Roeters van Lennep, J. E. & Kardys, I., 1 Jul 2021, In: International Journal of Cardiology. 334, p. 126-134 9 p.

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6 Citations (Scopus)

COVID-19-related myocarditis post-heart transplantation

Roest, S., Brugts, J. J., van Kampen, J. J. A., von der Thüsen, J. H., Constantinescu, A. A., Caliskan, K., Hirsch, A. & Manintveld, O. C., 1 Jun 2021, In: International Journal of Infectious Diseases. 107, p. 34-36 3 p.

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5 Citations (Scopus)

49 Downloads (Pure)

Influence of renal insufficiency pre-heart transplantation on malignancy risk post-heart transplantation

Roest, S., Struijk, C., Constantinescu, A. A., Caliskan, K., Plasmeijer, E. I., Boersma, E., Brugts, J. J. & Manintveld, O. C., Jun 2021, In: ESC heart failure. 8, 3, p. 2172-2182 11 p.

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1 Citation (Scopus)

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Left ventricular remodelling and prognosis after discharge in new-onset acute heart failure with reduced ejection fraction

van den Berge, J. C., Vroegindewey, M. M., Veenis, J. F., Brugts, J. J., Caliskan, K., Manintveld, O. C., Akkerhuis, K. M., Boersma, E., Deckers, J. W. & Constantinescu, A. A., 2 May 2021, In: ESC heart failure. 8, 4, p. 2679-2689 11 p.

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5 Citations (Scopus)

72 Downloads (Pure)

Concomitant endocarditis and spondylodiscitis due to coagulase-negative Staphylococci and a review of the literature

Houkes, K. M. G., Mudde, S. E., Constantinescu, A. A., Verkaik, N. J. & Yusuf, E., Jan 2021, In: IDCases. 24, e01100.

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1 Citation (Scopus)

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2020

Temporal patterns of macrophage- and neutrophil-related markers are associated with clinical outcome in heart failure patients

Klimczak-Tomaniak, D., Bouwens, E., Schuurman, A. S., Akkerhuis, K. M., Constantinescu, A., Brugts, J., Westenbrink, B. D., van Ramshorst, J., Germans, T., Pączek, L., Umans, V., Boersma, E. & Kardys, I., 1 Jun 2020, In: ESC heart failure. 7, 3, p. 1190-1200 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

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