dr. Antoinette Hollestelle

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20012021

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  • A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

    Coignard, J., Lush, M., GEMO Study Collaborators, EMBRACE Collaborators, kConFab Investigators, HEBON Investigators, ABCTB Investigators, Beesley, J., O’Mara, T. A., Dennis, J., Tyrer, J. P., Collee, J. M., Hollestelle, A., Jager, A., Martens, J. W. M., Andrieu, N. & Antoniou, A. C., 17 Feb 2021, In: Nature Communications. 12, 1, 1078.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
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    3 Citations (Scopus)
    2 Downloads (Pure)
  • Breast cancer risk genes - Association analysis in more than 113,000 women

    Dorling, L., Carvalho, S., Allen, J., González-Neira, A., Luccarini, C., Wahlström, C., Pooley, KA., Parsons, MT., Fortuno, C., Wang, Q., Bolla, MK., Dennis, J., Keeman, R., Alonso, MR., Álvarez, N., Herraez, B., Fernandez, V., Núñez-Torres, R., Osorio, A., Valcich, J. & 177 others, Li, M., Törngren, T., Harrington, PA., Baynes, C., Conroy, D. M., Decker, B., Fachal, L., Mavaddat, N., Ahearn, T., Aittomäki, K., Antonenkova, NN., Arnold, N., Arveux, P., Ausems, MG., Auvinen, P., Becher, H., Beckmann, MW., Behrens, S., Bermisheva, M., Bia?kowska, K., Blomqvist, C., Bogdanova, NV., Bogdanova-Markov, N., Bojesen, SE., Bonanni, B., Børresen-Dale, AL., Brauch, H., Bremer, M., Briceno, I., Brüning, T., Burwinkel, B., Cameron, DA., Camp, NJ., Campbell, A., Carracedo, A., Castelao, JE., Cessna, MH., Chanock, SJ., Christiansen, H., Collée, JM., Cordina-Duverger, E., Cornelissen, S., Czene, K., Dörk, T., Ekici, AB., Engel, C., Eriksson, M., Fasching, PA., Figueroa, J., Flyger, H., Försti, A., Gabrielson, M., Gago-Dominguez, M., Georgoulias, V., Gil, F., Giles, GG., Glendon, G., Garcia, EBG., Grenaker Alnæs, GI., Guénel, P., Hadjisavvas, A., Haeberle, L., Hahnen, E., Hall, P., Hamann, U., Harkness, EF., Hartikainen, JM., Hartman, M., He, W., Heemskerk - Gerritsen, A., Hillemanns, P., Hogervorst, FB., Hollestelle, A., Ho, WK., Hooning, M., Howell, A., Humphreys, K., Idris, F., Jakubowska, A., Jung, A., Kapoor, PM., Kerin, MJ., Khusnutdinova, E., Kim, SW., Ko, YD., Kosma, VM., Kristensen, VN., Kyriacou, K., Lakeman, IMM., Lee, J. W., Lee, MH., Li, J., Lindblom, A., Lo, WY., Loizidou, MA., Lophatananon, A., Lubi?ski, J., MacInnis, R. J., Madsen, MJ., Mannermaa, A., Manoochehri, M., Manoukian, S., Margolin, S., Martinez, M. E., Maurer, T., Mavroudis, D., McLean, C., Meindl, A., Mensenkamp, AR., Michailidou, K., Miller, N., Taib, NA., Muir, K., Mulligan, AM., Nevanlinna, H., Newman, WG., Nordestgaard, BG., Ng, PS., Oosterwijk, JC., Park, SK., Park-Simon, TW., Perez, JIA., Peterlongo, P., Porteous, DJ., Prajzendanc, K., Prokofyeva, D., Radice, P., Rashid, MU., Rhenius, V., Rookus, MA., Rüdiger, T., Saloustros, E., Sawyer, EJ., Schmutzler, RK., Schneeweiss, A., Schürmann, P., Shah, M., Sohn, C., Southey, MC., Surowy, H., Suvanto, M., Thanasitthichai, S., Tomlinson, I., Torres, D., Truong, T., Tzardi, M., Valova, Y., van Asperen, CJ., van Dam, RM., van den Ouweland, A., van der Kolk, LE., van Veen, EM., Wendt, C., Williams, JA., Yang, XR., Yoon, SY., Zamora, MP., Evans, DGR., de la Hoya, M., Simard, J., Antoniou, AC., Borg, Å., Andrulis, IL., Chang-Claude, J., García-Closas, M., Chenevix-Trench, G., Milne, RL., Pharoah, PD., Schmidt, MK., Spurdle, AB., Vreeswijk, MP., Benitez, J., Dunning, AM., Kvist, A., Teo, SH., Devilee, P. & Easton, DF., 2021, In: New England Journal of Medicine. 384, 5, p. 428-439 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    148 Citations (Scopus)
  • Functional annotation of the 2q35 breast cancer risk locus implicates a structural variant in influencing activity of a long-range enhancer element

    Baxter, J. S., Johnson, N., kConFab Investigators, NBCS Collaborators, ABCTB Investigators, Tomczyk, K., Gillespie, A., Maguire, S., Brough, R., Fachal, L., Michailidou, K., Bolla, M. K., Wang, Q., Dennis, J., Ahearn, T. U., Andrulis, I. L., Anton-Culver, H., Antonenkova, N. N., Arndt, V., Aronson, K. J. & 36 others, Augustinsson, A., Becher, H., Beckmann, M. W., Behrens, S., Benitez, J., Bermisheva, M., Bogdanova, N. V., Bojesen, S. E., Brenner, H., Brucker, S. Y., Cai, Q., Campa, D., Canzian, F., Castelao, J. E., Chan, T. L., Chang-Claude, J., Chanock, S. J., Chenevix-Trench, G., Choi, J. Y., Clarke, C. L., Colonna, S., Conroy, D. M., Couch, F. J., Cox, A., Cross, S. S., Czene, K., Daly, M. B., Engel, C., Hollestelle, A., Jager, A., Kraft, P., van den Ouweland, A. M. W., Haider, S., Ekici, A. B., Orr, N. & Fletcher, O., 1 Jul 2021, In: American Journal of Human Genetics. 108, 7, p. 1190-1203 14 p.

    Research output: Contribution to journalArticleAcademicpeer-review

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    1 Citation (Scopus)
    4 Downloads (Pure)
  • The predictive ability of the 313 variant–based polygenic risk score for contralateral breast cancer risk prediction in women of European ancestry with a heterozygous BRCA1 or BRCA2 pathogenic variant

    Lakeman, I. M. M., van den Broek, A. J., GEMO Study Collaborators, EMBRACE Collaborators, OCGN Investigators, HEBON Investigators, kConFab Investigators, Vos, J. A. M., Barnes, D. R., Adlard, J., Andrulis, I. L., Arason, A., Arnold, N., Arun, B. K., Balmaña, J., Barrowdale, D., Benitez, J., Borg, A., Caldés, T., Caligo, M. A. & 29 others, Chung, W. K., Claes, K. B. M., Barouk-Simonet, E., Belotti, M., Berthet, P., Bignon, Y. J., Bonadona, V., Bressac-de Paillerets, B., Buecher, B., Caputo, S., Caron, O., Castera, L., Caux-Moncoutier, V., Colas, C., Collonge-Rame, M. A., Coupier, I., de Pauw, A., Delnatte, C., Elan, C., Faivre, L., Ferrer, S. F., Gauthier-Villars, M., Gesta, P., Giraud, S., Collée, J. M., Engel, C., Hooning, M. J., Robson, M. & Schmidt, M. K., Sep 2021, In: Genetics in Medicine. 23, 9, p. 1726-1737 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    Open Access
    File
    1 Citation (Scopus)
    5 Downloads (Pure)
  • Breast Cancer Polygenic Risk Score and Contralateral Breast Cancer Risk

    Kramer, I., Hooning, M., Mavaddat, N., Hauptmann, M., Keeman, R., Steyerberg, E., Giardiello, D., Antoniou, AC., Pharoah, P., Canisius, S., Abu-Ful, Z., Andrulis, IL., Anton-Culver, H., Aronson, KJ., Augustinsson, A., Becher, H., Beckmann, MW., Behrens, S., Benitez, J., Bermisheva, M. & 25 others, Bogdanova, NV., Bojesen, S., Bolla, M., Bonanni, B., Brauch, H., Bremer, M., Brucker, SY., Burwinkel, B., Castelao, JE., Chan, T., Chang-Claude, J., Chanock, SJ., Chenevix-Trench, G., Choi, J., Clarke, CL., Collee, M., Couch, FJ., Cox, A., Cross, S., Czene, K., Daly, MB., Heemskerk - Gerritsen, A., Hollestelle, A., Hall, P. & Schmidt, M., 2020, In: American Journal of Human Genetics. 107, 5, p. 837-848 12 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    12 Citations (Scopus)