Bernadette van den Hoogen

2025

Cell-derived Newcastle disease virus variant with two amino acid substitutions near cleavage site of F shows favorable traits as oncolytic virus

Huberts, M., de Graaf, J. F., Groeneveld, D., van Nieuwkoop, S., Fouchier, R. A. M. & van den Hoogen, B. G., 20 Mar 2025, In: Molecular Therapy Oncology. 33, 1, 200915.

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The role of M2 proteins of pneumoviruses in transcription regulation, prevention of hypermutation, and activation of the type I interferon pathway

Ribó-Molina, P., Groen, K., Susma, B., Van Nieuwkoop, S., Funk, M., Fouchier, R. A. M. & Van Den Hoogen, B. G., 25 Feb 2025, In: Journal of Virology. 99, 2, e01243-24.

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2024

The heterogeneous sensitivity of pediatric brain tumors to different oncolytic viruses is predicted by unique gene expression profiles

Vazaios, K., Stavrakaki, Ε., Vogelezang, L. B., Ju, J., Waranecki, P., Metselaar, D. S., Meel, M. H., Kemp, V., van den Hoogen, B. G., Hoeben, R. C., Chiocca, E. A., Goins, W. F., Stubbs, A., Li, Y., Alonso, M. M., Calkoen, F. G., Hulleman, E., van der Lugt, J. & Lamfers, M. L. M., 1 Jun 2024, In: Molecular Therapy. 32, 2, 200804.

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3 Citations (Scopus)

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Human metapneumovirus infection of organoid-derived human bronchial epithelium represents cell tropism and cytopathology as observed in in vivo models

Ribo-Molina, P., van Nieuwkoop, S., Mykytyn, A. Z., van Run, P., Lamers, M. M., Haagmans, B. L., Fouchier, R. A. M. & van den Hoogen, B. G., 28 Feb 2024, In: mSphere. 9, 2, p. e0074323 13 p.

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7 Citations (Scopus)

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2023

4-Octyl itaconate reduces influenza A replication by targeting the nuclear export protein CRM1

Ribó-Molina, P., Weiss, H., Susma, B., van Nieuwkoop, S., Persoons, L., Zheng, Y., Ruzek, M., Daelemans, D., Fouchier, R., O'Neill, L. & van den Hoogen, B., 12 Oct 2023, In: Journal of Virology. 97, 10, 15 p., e0132523.

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11 Citations (Scopus)

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Viral sensing by epithelial cells involves PKR- and caspase-3-dependent generation of gasdermin E pores

Guy, C., Baran, M., Ribó-Molina, P., van den Hoogen, B. G. & Bowie, A. G., 15 Sept 2023, In: iScience. 26, 9, 107698.

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8 Citations (Scopus)

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Annual (2023) taxonomic update of RNA-directed RNA polymerase-encoding negative-sense RNA viruses (realm Riboviria: kingdom Orthornavirae: phylum Negarnaviricota)

Kuhn, J. H., Abe, J., Adkins, S., Alkhovsky, S. V., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Kumar Baranwal, V., Beer, M., Bejerman, N., Bergeron, É., Biedenkopf, N., Blair, C. D., Blasdell, K. R., Blouin, A. G., Bradfute, S. B., Briese, T. & Brown, P. A. & 167 others, Buchholz, U. J., Buchmeier, M. J., Bukreyev, A., Burt, F., Büttner, C., Calisher, C. H., Cao, M., Casas, I., Chandran, K., Charrel, R. N., Kumar Chaturvedi, K., Chooi, K. M., Crane, A., Dal Bó, E., Carlos de la Torre, J., de Souza, W. M., de Swart, R. L., Debat, H., Dheilly, N. M., Di Paola, N., Di Serio, F., Dietzgen, R. G., Digiaro, M., Drexler, J. F., Duprex, W. P., Dürrwald, R., Easton, A. J., Elbeaino, T., Ergünay, K., Feng, G., Firth, A. E., Fooks, A. R., Formenty, P. B. H., Freitas-Astúa, J., Gago-Zachert, S., Laura García, M., García-Sastre, A., Garrison, A. R., Gaskin, T. R., Gong, W., Gonzalez, J. P. J., de Bellocq, J. G., Griffiths, A., Groschup, M. H., Günther, I., Günther, S., Hammond, J., Hasegawa, Y., Hayashi, K., Hepojoki, J., Higgins, C. M., Hongō, S., Horie, M., Hughes, H. R., Hume, A. J., Hyndman, T. H., Ikeda, K., Jiāng, D., Jonson, G. B., Junglen, S., Klempa, B., Klingström, J., Kondō, H., Koonin, E. V., Krupovic, M., Kubota, K., Kurath, G., Laenen, L., Lambert, A. J., Lǐ, J., Li, J. M., Liu, R., Lukashevich, I. S., MacDiarmid, R. M., Maes, P., Marklewitz, M., Marshall, S. H., Marzano, S. Y. L., McCauley, J. W., Mirazimi, A., Mühlberger, E., Nabeshima, T., Naidu, R., Natsuaki, T., Navarro, B., Navarro, J. A., Neriya, Y., Netesov, S. V., Neumann, G., Nowotny, N., Nunes, M. R. T., Ochoa-Corona, F. M., Okada, T., Palacios, G., Pallás, V., Papa, A., Paraskevopoulou, S., Parrish, C. R., Pauvolid-Corrêa, A., Pawęska, J. T., Pérez, D. R., Pfaff, F., Plemper, R. K., Postler, T. S., Rabbidge, L. O., Radoshitzky, S. R., Ramos-González, P. L., Rehanek, M., Resende, R. O., Reyes, C. A., Rodrigues, T. C. S., Romanowski, V., Rubbenstroth, D., Rubino, L., Runstadler, J. A., Sabanadzovic, S., Sadiq, S., Salvato, M. S., Sasaya, T., Schwemmle, M., Sharpe, S. R., Shi, M., Shimomoto, Y., Kavi Sidharthan, V., Sironi, M., Smither, S., Song, J. W., Spann, K. M., Spengler, J. R., Stenglein, M. D., Takada, A., Takeyama, S., Tatara, A., Tesh, R. B., Thornburg, N. J., Tian, X., Tischler, N. D., Tomitaka, Y., Tomonaga, K., Tordo, N., Tu, C., Turina, M., Tzanetakis, I. E., Maria Vaira, A., van den Hoogen, B., Vanmechelen, B., Vasilakis, N., Verbeek, M., von Bargen, S., Wada, J., Wahl, V., Walker, P. J., Waltzek, T. B., Whitfield, A. E., Wolf, Y. I., Xia, H., Xylogianni, E., Yanagisawa, H., Yano, K., Ye, G., Yuan, Z., Zerbini, F. M., Zhang, G., Zhang, S., Zhang, Y. Z., Zhao, L. & Økland, A. L., 1 Aug 2023, In: The Journal of general virology. 104, 8, 001864.

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37 Citations (Scopus)

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Emergence and Potential Extinction of Genetic Lineages of Human Metapneumovirus between 2005 and 2021

Groen, K., Van Nieuwkoop, S., Meijer, A., Van Der Veer, B., van Kampen, J. J. A., Fraaij, P. L., Fouchier, R. A. M. & Van Den Hoogen, B. G., Feb 2023, In: mBio. 14, 1

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10 Citations (Scopus)

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2022

2022 taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Kuhn, J. H., Adkins, S., Alkhovsky, S. V., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Bandte, M., Beer, M., Bejerman, N., Bergeron, É., Biedenkopf, N., Bigarré, L., Blair, C. D., Blasdell, K. R., Bradfute, S. B., Briese, T., Brown, P. A. & Bruggmann, R. & 161 others, Buchholz, U. J., Buchmeier, M. J., Bukreyev, A., Burt, F., Büttner, C., Calisher, C. H., Candresse, T., Carson, J., Casas, I., Chandran, K., Charrel, R. N., Chiaki, Y., Crane, A., Crane, M., Dacheux, L., Bó, E. D., de la Torre, J. C., de Lamballerie, X., de Souza, W. M., de Swart, R. L., Dheilly, N. M., Di Paola, N., Di Serio, F., Dietzgen, R. G., Digiaro, M., Drexler, J. F., Duprex, W. P., Dürrwald, R., Easton, A. J., Elbeaino, T., Ergünay, K., Feng, G., Feuvrier, C., Firth, A. E., Fooks, A. R., Formenty, P. B. H., Freitas-Astúa, J., Gago-Zachert, S., García, M. L., García-Sastre, A., Garrison, A. R., Godwin, S. E., Gonzalez, J. P. J., de Bellocq, J. G., Griffiths, A., Groschup, M. H., Günther, S., Hammond, J., Hepojoki, J., Hierweger, M. M., Hongō, S., Horie, M., Horikawa, H., Hughes, H. R., Hume, A. J., Hyndman, T. H., Jiāng, D., Jonson, G. B., Junglen, S., Kadono, F., Karlin, D. G., Klempa, B., Klingström, J., Koch, M. C., Kondō, H., Koonin, E. V., Krásová, J., Krupovic, M., Kubota, K., Kuzmin, I. V., Laenen, L., Lambert, A. J., Lǐ, J., Li, J. M., Lieffrig, F., Lukashevich, I. S., Luo, D., Maes, P., Marklewitz, M., Marshall, S. H., Marzano, S. Y. L., McCauley, J. W., Mirazimi, A., Mohr, P. G., Moody, N. J. G., Morita, Y., Morrison, R. N., Mühlberger, E., Naidu, R., Natsuaki, T., Navarro, J. A., Neriya, Y., Netesov, S. V., Neumann, G., Nowotny, N., Ochoa-Corona, F. M., Palacios, G., Pallandre, L., Pallás, V., Papa, A., Paraskevopoulou, S., Parrish, C. R., Pauvolid-Corrêa, A., Pawęska, J. T., Pérez, D. R., Pfaff, F., Plemper, R. K., Postler, T. S., Pozet, F., Radoshitzky, S. R., Ramos-González, P. L., Rehanek, M., Resende, R. O., Reyes, C. A., Romanowski, V., Rubbenstroth, D., Rubino, L., Rumbou, A., Runstadler, J. A., Rupp, M., Sabanadzovic, S., Sasaya, T., Schmidt-Posthaus, H., Schwemmle, M., Seuberlich, T., Sharpe, S. R., Shi, M., Sironi, M., Smither, S., Song, J. W., Spann, K. M., Spengler, J. R., Stenglein, M. D., Takada, A., Tesh, R. B., Těšíková, J., Thornburg, N. J., Tischler, N. D., Tomitaka, Y., Tomonaga, K., Tordo, N., Tsunekawa, K., Turina, M., Tzanetakis, I. E., Vaira, A. M., van den Hoogen, B., Vanmechelen, B., Vasilakis, N., Verbeek, M., von Bargen, S., Wada, J., Wahl, V., Walker, P. J., Whitfield, A. E., Williams, J. V., Wolf, Y. I., Yamasaki, J., Yanagisawa, H., Ye, G., Zhang, Y. Z. & Økland, A. L., Dec 2022, In: Archives of Virology. 167, 12, p. 2857-2906 50 p.

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52 Citations (Scopus)

Evidence against the Human Metapneumovirus G, SH, and M2-2 Proteins as Bona Fide Interferon Antagonists

Groen, K., van Nieuwkoop, S., Lamers, M. M., Fouchier, R. A. M. & van den Hoogen, B. G., Sept 2022, In: Journal of Virology. 96, 17, e0072322.

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Fetal Transfer of Human Metapneumovirus-Neutralizing Antibodies Is Reduced From Mothers Living With HIV-1

Ramocha, L. M., van den Hoogen, B. G., Baillie, V., van Nieuwkoop, S., Cutland, C. L., Jones, S., Moultrie, A., Izu, A., Verwey, C., Madhi, S. A. & Dorfman, J. R., 1 Jul 2022, In: Journal of the Pediatric Infectious Diseases Society. 11, 7, p. 341-344 4 p.

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Comparison between intratumoral and intravenously administered oncolytic virus therapy with Newcastle disease virus in a xenograft murine model for pancreatic adenocarcinoma

de Graaf, J. F., Huberts, M., Groeneveld, D., van Nieuwkoop, S., van Eijck, C. H. J., Fouchier, R. A. M. & van den Hoogen, B. G., Jul 2022, In: Heliyon. 8, 7, e09915.

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Assessment of the virulence for chickens of Newcastle Disease virus with an engineered multi-basic cleavage site in the fusion protein and disrupted V protein gene

de Graaf, J. F., van Nieuwkoop, S., de Meulder, D., Lexmond, P., Kuiken, T., Groeneveld, D., Fouchier, R. A. M. & van den Hoogen, B. G., Jun 2022, In: Veterinary Microbiology. 269, 109437.

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Optimizing environmental safety and cell-killing potential of oncolytic Newcastle Disease virus with modifications of the V, F and HN genes

de Graaf, J. F., van Nieuwkoop, S., Bestebroer, T., Groeneveld, D., van Eijck, C. H. J., Fouchier, R. A. M. & van den Hoogen, B. G., 9 Feb 2022, In: PLoS ONE. 17, 2 February, e0263707.

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2021

2021 Taxonomic update of phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Kuhn, J. H., Adkins, S., Agwanda, B. R., Al Kubrusli, R., Alkhovsky, S. V., Amarasinghe, G. K., Avšič-Županc, T., Ayllón, M. A., Bahl, J., Balkema-Buschmann, A., Ballinger, M. J., Basler, C. F., Bavari, S., Beer, M., Bejerman, N., Bennett, A. J., Bente, D. A., Bergeron, É., Bird, B. H. & Blair, C. D. & 231 others, Blasdell, K. R., Blystad, D. R., Bojko, J., Borth, W. B., Bradfute, S., Breyta, R., Briese, T., Brown, P. A., Brown, J. K., Buchholz, U. J., Buchmeier, M. J., Bukreyev, A., Burt, F., Büttner, C., Calisher, C. H., Cao, M., Casas, I., Chandran, K., Charrel, R. N., Cheng, Q., Chiaki, Y., Chiapello, M., Choi, I. R., Ciuffo, M., Clegg, J. C. S., Crozier, I., Dal Bó, E., de la Torre, J. C., de Lamballerie, X., de Swart, R. L., Debat, H., Dheilly, N. M., Di Cicco, E., Di Paola, N., Di Serio, F., Dietzgen, R. G., Digiaro, M., Dolnik, O., Drebot, M. A., Drexler, J. F., Dundon, W. G., Duprex, W. P., Dürrwald, R., Dye, J. M., Easton, A. J., Ebihara, H., Elbeaino, T., Ergünay, K., Ferguson, H. W., Fooks, A. R., Forgia, M., Formenty, P. B. H., Fránová, J., Freitas-Astúa, J., Fu, J., Fürl, S., Gago-Zachert, S., Gāo, G. F., García, M. L., García-Sastre, A., Garrison, A. R., Gaskin, T., Gonzalez, J. P. J., Griffiths, A., Goldberg, T. L., Groschup, M. H., Günther, S., Hall, R. A., Hammond, J., Han, T., Hepojoki, J., Hewson, R., Hong, J., Hong, N., Hongo, S., Horie, M., Hu, J. S., Hu, T., Hughes, H. R., Hüttner, F., Hyndman, T. H., Ilyas, M., Jalkanen, R., Jiāng, D., Jonson, G. B., Junglen, S., Kadono, F., Kaukinen, K. H., Kawate, M., Klempa, B., Klingström, J., Kobinger, G., Koloniuk, I., Kondō, H., Koonin, E. V., Krupovic, M., Kubota, K., Kurath, G., Laenen, L., Lambert, A. J., Langevin, S. L., Lee, B., Lefkowitz, E. J., Leroy, E. M., Li, S., Li, L., Lǐ, J., Liu, H., Lukashevich, I. S., Maes, P., de Souza, W. M., Marklewitz, M., Marshall, S. H., Marzano, S. Y. L., Massart, S., McCauley, J. W., Melzer, M., Mielke-Ehret, N., Miller, K. M., Ming, T. J., Mirazimi, A., Mordecai, G. J., Mühlbach, H. P., Mühlberger, E., Naidu, R., Natsuaki, T., Navarro, J. A., Netesov, S. V., Neumann, G., Nowotny, N., Nunes, M. R. T., Olmedo-Velarde, A., Palacios, G., Pallás, V., Pályi, B., Papa, A., Paraskevopoulou, S., Park, A. C., Parrish, C. R., Patterson, D. A., Pauvolid-Corrêa, A., Pawęska, J. T., Payne, S., Peracchio, C., Pérez, D. R., Postler, T. S., Qi, L., Radoshitzky, S. R., Resende, R. O., Reyes, C. A., Rima, B. K., Luna, G. R., Romanowski, V., Rota, P., Rubbenstroth, D., Rubino, L., Runstadler, J. A., Sabanadzovic, S., Sall, A. A., Salvato, M. S., Sang, R., Sasaya, T., Schulze, A. D., Schwemmle, M., Shi, M., Shí, X., Shí, Z., Shimomoto, Y., Shirako, Y., Siddell, S. G., Simmonds, P., Sironi, M., Smagghe, G., Smither, S., Song, J. W., Spann, K., Spengler, J. R., Stenglein, M. D., Stone, D. M., Sugano, J., Suttle, C. A., Tabata, A., Takada, A., Takeuchi, S., Tchouassi, D. P., Teffer, A., Tesh, R. B., Thornburg, N. J., Tomitaka, Y., Tomonaga, K., Tordo, N., Torto, B., Towner, J. S., Tsuda, S., Tu, C., Turina, M., Tzanetakis, I. E., Uchida, J., Usugi, T., Vaira, A. M., Vallino, M., van den Hoogen, B., Varsani, A., Vasilakis, N., Verbeek, M., von Bargen, S., Wada, J., Wahl, V., Walker, P. J., Wang, L. F., Wang, G., Wang, Y., Wang, Y., Waqas, M., Wèi, T., Wen, S., Whitfield, A. E., Williams, J. V., Wolf, Y. I., Wu, J., Xu, L., Yanagisawa, H., Yang, C., Yang, Z., Zerbini, F. M., Zhai, L., Zhang, Y. Z., Zhang, S., Zhang, J., Zhang, Z. & Zhou, X., Dec 2021, In: Archives of Virology. 166, 12, p. 3513-3566 54 p.

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68 Citations (Scopus)

Whole genome sequencing of human metapneumoviruses from clinical specimens using MinION nanopore technology

Groen, K., van Nieuwkoop, S., Bestebroer, T. M., Fraaij, P. L., Fouchier, R. A. M. & van den Hoogen, B. G., Sept 2021, In: Virus Research. 302, 198490.

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Rintatolimod induces antiviral activities in human pancreatic cancer cells: Opening for an anti-covid-19 opportunity in cancer patients?

Mustafa, D. A. M., Saida, L., Latifi, D., Wismans, L. V., de Koning, W., Zeneyedpour, L., Luider, T. M., van den Hoogen, B. & van Eijck, C. H. J., 9 Jun 2021, In: Cancers. 13, 12, 2896.

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Clinical impact of human metapneumovirus infections before and during the COVID-19 pandemic

Jongbloed, M., Leijte, W. T., Linssen, C. F. M., van den Hoogen, B. G., van Gorp, E. C. M. & de Kruif, M. D., 2021, In: Infectious Diseases. 53, 7, p. 488-497 10 p.

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2020

2020 taxonomic update for phylum Negarnaviricota (Riboviria: Orthornavirae), including the large orders Bunyavirales and Mononegavirales

Kuhn, J. H., Adkins, S., Alioto, D., Alkhovsky, S., Amarasinghe, G. K., Anthony, S., Avši?-Županc, T., Ayllón, M., Bahl, J., Balkema-Buschmann, A., Ballinger, M., Bartoni?ka, T., Basler, C., Bavari, S., Beer, M., Bente, D., Bergeron, É., Bird, B., Blair, C. & Blasdell, K. R. & 209 others, Bradfute, S., Breyta, R., Briese, T., Brown, P., Buchholz, U., Buchmeier, M., Bukreyev, A., Burt, F., Buzkan, N., Calisher, C. H., Cao, M., Casas, I., Chamberlain, J., Chandran, K., Charrel, R. N., Chen, B., Chiumenti, M., Choi, I., Clegg, J., Crozier, I., da Graça, J., Dal Bó, E., Dávila, A., de la Torre, J., de Lamballerie, X., Swart, R., Di Bello, P., Di Paola, N., Di Serio, F., Dietzgen, R. G., Digiaro, M., Dolja, V., Dolnik, O., Drebot, M., Drexler, J., Dürrwald, R., Dufkova, L., Dundon, W., Duprex, W., Dye, J. M., Easton, A. J., Ebihara, H., Elbeaino, T., Ergünay, K., Fernandes, J., Fooks, A., Formenty, P., Forth, L., Fouchier, R., Freitas-Astúa, J., Gago-Zachert, S., G?o, G., García, M., García-Sastre, A., Garrison, A., Gbakima, A., Goldstein, T., Gonzalez, J., Griffiths, A., Groschup, M., Günther, S., Guterres, A., Hall, R., Hammond, J., Hassan, M., Hepojoki, J., Hepojoki, S., Hetzel, U., Hewson, R., Hoffmann, B., Hongo, S., Höper, D., Horie, M., Hughes, H., Hyndman, T. H., Jambai, A., Jardim, R., Ji?ng, D., Jin, Q., Jonson, G., Junglen, S., Karada?, S., Keller, K., Klempa, B., Klingström, J., Kobinger, G., Kond?, H., Koonin, E., Krupovic, M., Kurath, G., Kuzmin, I., Laenen, L., Lamb, R. A., Lambert, A., Langevin, S., Lee, B., Lemos, E., Leroy, E., Li, D., L?, J., Liang, M., Liú, W., Liú, Y., Lukashevich, I., Maes, P., Souza, W., Marklewitz, M., Marshall, S., Martelli, G., Martin, R., Marzano, S., Massart, S., McCauley, J. W., Mielke-Ehret, N., Minafra, A., Minutolo, M., Mirazimi, A., Mühlbach, H., Mühlberger, E., Naidu, R., Natsuaki, T., Navarro, B., Navarro, J., Netesov, S. V., Neumann, G., Nowotny, N., Nunes, M., Nylund, A., Økland, A., Oliveira, R., Palacios, G., Pallas, V., Pályi, B., Papa, A., Parrish, C., Pauvolid-Corrêa, A., Paw?ska, J., Payne, S., Pérez, D., Pfaff, F., Radoshitzky, S., Rahman, A., Ramos-González, P., Resende, R., Reyes, C., Rima, B., Romanowski, V., Robles Luna, G., Rota, P., Rubbenstroth, D., Runstadler, J., Ruzek, D., Sabanadzovic, S., Salát, J., Sall, A., Salvato, M., Sarpkaya, K., Sasaya, T., Schwemmle, M., Shabbir, M., Shí, X., Shí, Z., Shirako, Y., Simmonds, P., Širmarová, J., Sironi, M., Smither, S., Smura, T., Song, J., Spann, K., Spengler, J., Stenglein, M. D., Stone, D. M., Straková, P., Takada, A., Tesh, R., Thornburg, N., Tomonaga, K., Tordo, N., Towner, J. S., Turina, M., Tzanetakis, I., Ulrich, R., Vaira, A., van den Hoogen, B., Varsani, A., Vasilakis, N., Verbeek, M., Wahl, V., Walker, P. J., Wang, H., Wang, J., Wang, X., Wang, L., Wèi, T., Wells, H., Whitfield, A. E., Williams, J., Wolf, Y., Wú, Z., Yang, X., Yáng, X., Yu, X., Yutin, N., Zerbini, F., Zhang, T., Zhang, Y. Z., Zhou, G. & Zhou, X., 2020, In: Archives of Virology. 165, 12, p. 3023-3072 50 p.

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179 Citations (Scopus)

Determinants of the efficacy of viro-immunotherapy: A review

de Graaf, J., Huberts, M., Fouchier, R. & van den Hoogen, B., 2020, In: Cytokine and Growth Factor Reviews. 56, p. 124-132 9 p.

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9 Citations (Scopus)

27 Downloads (Pure)

Developing oncolytic viruses for clinical use: A consortium approach

Kemp, V., Lamfers, M., van der Pluijm, G., van den Hoogen, B. & Hoeben, R., 2020, In: Cytokine and Growth Factor Reviews. 56, p. 133-140 8 p.

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14 Citations (Scopus)

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Immunometabolism pathways as the basis for innovative anti-viral strategies (INITIATE): A Marie Sklodowska-Curie innovative training network

van den Hoogen, B., Santoni, A., Sciume, G., Bowie, A., O'Farrelly, C., O'Neill, L., Anthonsen, M., Pardali, K., Young, S., Bergthaler, A., Manel, N., Zahn, R., Kikkert, M., Snijder, E., van Kuppeveld, F., Fouchier, R. & Hiscott, J., 2020, In: Virus Research. 287, 198094.

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3 Citations (Scopus)

21 Downloads (Pure)

2019

ADAR1: "Editor-in-Chief" of Cytoplasmic Innate Immunity

Lamers, M., van den Hoogen, B. & Haagmans, B., 2019, In: Frontiers in Immunology. 10, 1763.

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141 Citations (Scopus)

27 Downloads (Pure)

Taxonomy of the order Mononegavirales: second update 2018

Maes, P., Amarasinghe, G. K., Ayllon, M., Basler, C. F., Bavari, S., Blasdell, K. R., de Swart, R., Fouchier, R., van den Hoogen, B., Zhang, Y. Z. & Kuhn, J. H., 2019, In: Archives of Virology. 164, 4, p. 1233-1244 12 p.

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80 Citations (Scopus)

Taxonomy of the order Mononegavirales: update 2019

Amarasinghe, G. K., Ayllon, M., Bao, Y., Basler, C. F., Bavari, S., Blasdell, K. R., de Swart, R., Fouchier, R., van den Hoogen, B., Zhang, Y. Z. & Kuhn, J. H., 2019, In: Archives of Virology. 164, 7, p. 1967-1980 14 p.

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260 Citations (Scopus)

2018

Armed oncolytic viruses: A kick-start for anti-tumor immunity

de Graaf, J., Vor, L., Fouchier, R. & van den Hoogen, B., 2018, In: Cytokine & Growth Factor Reviews. 41, p. 28-39 12 p.

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125 Citations (Scopus)

26 Downloads (Pure)

Zoonotic Infection With Pigeon Paramyxovirus Type 1 Linked to Fatal Pneumonia

Kuiken, T., Breitbart, M., Beer, M., Grund, C., Hoper, D., van den Hoogen, B., Kerkhoffs, J., Kroes, A., Rosario, K., van Run, P., Schwarz, M., Svraka, S., Teifke, J. & Koopmans, M., 2018, In: Journal of Infectious Diseases. 218, 7, p. 1037-1044 8 p.

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15 Citations (Scopus)

2017

Cerebrospinal Fluid Findings in an Adult with Human Metapneumovirus-Associated Encephalitis

Jeannet, N., van den Hoogen, B., Schefold, J., Suter-Riniker, F. & Sommerstein, R., 2017, In: Emerging Infectious Diseases. 23, 2, p. 370-370 1 p.

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11 Citations (Scopus)

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Pigeon paramyxovirus type 1 from a fatal human case induces pneumonia in experimentally infected cynomolgus macaques (Macaca fascicularis)

Kuiken, T., Buijs, P., van Run, P., Amerongen, G., Koopmans, M. & van den Hoogen, B., 2017, In: Veterinary Research. 48, 80.

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8 Citations (Scopus)

11 Downloads (Pure)

Recovery of a Paramyxovirus, the Human Metapneumovirus, from Cloned cDNA

van den Hoogen, B. & Fouchier, R., 2017, In: Methods in Molecular Biology. 1602, p. 125-139 15 p.

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2 Citations (Scopus)

2016

Antiviral Activity of Favipiravir (T-705) against a Broad Range of Paramyxoviruses In Vitro and against Human Metapneumovirus in Hamsters

Jochmans, D., van Nieuwkoop, S., Smits, S., Neyts, J., Fouchier, R. & van den Hoogen, B., 2016, In: Antimicrobial Agents & Chemotherapy. 60, 8, p. 4620-4629 10 p.

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54 Citations (Scopus)

2015

In vitro screening of clinical drugs identifies sensitizers of oncolytic viral therapy in glioblastoma stem-like cells

Berghauser Pont, L., Balvers, R., Kloezeman, J., Nowicki, M., van den Bossche, W., Kremer, A., Wakimoto, H., van den Hoogen, B., Leenstra, S., Dirven, C., Chiocca, E., Lawler, S. & Lamfers, M., 2015, In: Gene Therapy. 22, 12, p. 947-959 13 p.

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14 Citations (Scopus)

Oncolytic viruses: From bench to bedside with a focus on safety

Buijs, P., Oldenampsen, J., van Eijck, C. & van den Hoogen, B., 2015, In: Human Vaccines & Immunotherapeutics. 11, 7, p. 1573-1584 12 p.

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111 Citations (Scopus)

Recombinant Immunomodulating Lentogenic or Mesogenic Oncolytic Newcastle Disease Virus for Treatment of Pancreatic Adenocarcinoma

Buijs, P., van Nieuwkoop, S., Vaes, V., Fouchier, R., van Eijck, C. & van den Hoogen, B., 2015, In: Viruses-Basel. 7, 6, p. 2980-2998 19 p.

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35 Citations (Scopus)

17 Downloads (Pure)

2014

Different responses of human pancreatic adenocarcinoma cell lines to oncolytic Newcastle disease virus infection

Buijs, P., van Eijck, C., Hofland, L., Fouchier, R. & van den Hoogen, B., 2014, In: Cancer Gene Therapy. 21, 1, p. 24-30 7 p.

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31 Citations (Scopus)

Excessive production and extreme editing of human metapneumovirus defective interfering RNA is associated with type I IFN induction

van den Hoogen, B., van Boheemen, S., Rijck, J., van Nieuwkoop, S., Smith, D., Laksono, B., Gultyaev, A., Osterhaus, A. & Fouchier, R., 2014, In: Journal of General Virology. 95, p. 1625-1633 9 p.

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38 Citations (Scopus)

Intravenously injected Newcastle disease virus in non-human primates is safe to use for oncolytic virotherapy

Buijs, P., Amerongen, G., van Nieuwkoop, S., Bestebroer, T., van Run, P., Kuiken, T., Fouchier, R., van Eijck, C. & van den Hoogen, B., 2014, In: Cancer Gene Therapy. 21, 11, p. 463-471 9 p.

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22 Citations (Scopus)

2013

MERS-coronavirus replication induces severe in vitro cytopathology and is strongly inhibited by cyclosporin A or interferon-alpha treatment

de Wilde, A., Victor, S., Oudshoorn, D., Bestebroer, T., van Nieuwkoop, S., Limpens, R., Posthuma, C., van der Meer, Y., Barcena, M., Haagmans, B., Snijder, E. & van den Hoogen, B., 2013, In: Journal of General Virology. 94, p. 1749-1760 12 p.

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301 Citations (Scopus)

Paramyxovirus infections in ex vivo lung slice cultures of different host species

Nguyen, T., de Vries, R., Ludlow, M., van den Hoogen, B., Lemon, K., Amerongen, G., Osterhaus, A., de Swart, R. & Duprex, W., 2013, In: Journal of Virological Methods. 193, 1, p. 159-165 7 p.

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24 Citations (Scopus)

2011

Streptococcus pneumoniae exposure is associated with human metapneumovirus seroconversion and increased susceptibility to in vitro HMPV infection

Verkaik, N., Nguyen, T., de Vogel, C., Moll, H., Verbrugh, H., Jaddoe, V., Hofman, B., van Wamel, W., van den Hoogen, B., Offerman, L., Ludlow, M., de Witte, L., Osterhaus, A., Belkum, A. & de Swart, R., 2011, In: Clinical Microbiology and Infection. 17, 12, p. 1840-1844 5 p.

Research output: Contribution to journal › Article › Academic

51 Citations (Scopus)

2008

Generation of temperature-sensitive human metapneumovirus strains that provide protective immunity in hamsters

Herfst, S., de Graaf, M., Schrauwen, E., Sprong, L., Hussain, K., van den Hoogen, B., Osterhaus, A. & Fouchier, R., 2008, In: Journal of General Virology. 89, p. 1553-1562 10 p.

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36 Citations (Scopus)

Immunogenicity and efficacy of two candidate human metapneumovirus vaccines in cynomolgus macaques

Herfst, S., Schrauwen, E., de Graaf, M., Amerongen, G., van den Hoogen, B., de Swart, R., Osterhaus, A. & Fouchier, R., 2008, In: Vaccine. 26, 33, p. 4224-4230 7 p.

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44 Citations (Scopus)

Specificity and functional interaction of the polymerase complex proteins of human and avian metapneumoviruses

de Graaf, M., Herfst, S., Schrauwen, E., Choi, Y., van den Hoogen, B., Osterhaus, A. & Fouchier, R., 2008, In: Journal of General Virology. 89, p. 975-983 9 p.

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13 Citations (Scopus)

2007

An improved plaque reduction virus neutralization assay for human metapneumovirus

de Graaf, M., Herfst, S., Schrauwen, E., van den Hoogen, B., Osterhaus, A. & Fouchier, R., 2007, In: Journal of Virological Methods. 143, 2, p. 169-174 6 p.

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39 Citations (Scopus)

Experimental infection of macaques with human metapneumovirus induces transient protective immunity

van den Hoogen, B., Herfst, S., de Graaf, M., Sprong, L., Lavieren, R., Amerongen, G., Yüksel, S., Fouchier, R., Osterhaus, A. & de Swart, R., 2007, In: Journal of General Virology. 88, p. 1251-1259 9 p.

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48 Citations (Scopus)

Immunization of macaques with formalin-inactivated human metapneumovirus induces hypersensitivity to hMPV infection

de Swart, R., van den Hoogen, B., Kuiken, T., Herfst, S., Amerongen, G., Yüksel, S., Sprong, L. & Osterhaus, A., 2007, In: Vaccine. 25, 51, p. 8518-8528 11 p.

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57 Citations (Scopus)

Immunization of Syrian golden hamsters with F subunit vaccine of human metapneumovirus induces protection against challenge with homologous or heterologous strains

Herfst, S., de Graaf, M., Schrauwen, E., Ulbrandt, N., Barnes, A., Senthil, K., Osterhaus, A., Fouchier, R. & van den Hoogen, B., 2007, In: Journal of General Virology. 88, p. 2702-2709 8 p.

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53 Citations (Scopus)

2004

Antigenic and genetic variability of human metapneumoviruses

van den Hoogen, B., Herfst, S., Sprong, L., Cane, P., Forleo-Neto, E., de Swart, R., Osterhaus, A. & Fouchier, R., 2004, In: Emerging Infectious Diseases. 10, 4, p. 658-666 9 p.

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339 Citations (Scopus)

23 Downloads (Pure)

Experimental human metapneumovirus infection of cynomolgus macaques (Macaca fascicularis) results in virus replication in ciliated epithelial cells and pneumocytes with associated lesions throughout the respiratory tract

Kuiken, T., van den Hoogen, B., van Riel, D., Laman, J., Amerongen, G., Sprong, L., Fouchier, R. & Osterhaus, A., 2004, In: American Journal of Pathology. 164, 6, p. 1893-1900 8 p.

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135 Citations (Scopus)

10 Downloads (Pure)

Human metapneumovirus infection in hospital referred South African children

IJpma, F., Beekhuis, D., Cotton, M., Pieper, C., Kimpen, J., van den Hoogen, B., Doornum, G. & Osterhaus, A., 2004, In: Journal of Medical Virology. 73, p. 486-493 8 p.

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62 Citations (Scopus)

dr. Bernadette van den Hoogen

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