Bert Mik

2024

Evaluating the Prevalence of Cardiac Surgery–associated Acute Kidney Injury After Septal Myectomy Combined With Concomitant Procedures in Obstructive Hypertrophic Cardiomyopathy

de Wijs, C. J., Schoonvelde, S. A. C., Mik, E. G., de Jong, P. L., Michels, M. & Harms, F. A., Oct 2024, In: Journal of Cardiothoracic and Vascular Anesthesia. 38, 10, p. 2254-2260 7 p.

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Mitochondrial oxygen tension in critically ill patients receiving red blood cell transfusions: a multicenter observational cohort study

Baysan, M., Hilderink, B., van Manen, L., Caram-Deelder, C., Mik, E. G., Juffermans, N. P., van der Bom, J. G. & Arbous, M. S., 8 Jul 2024, In: Intensive Care Medicine Experimental. 12, 1, 61.

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Description of mitochondrial oxygen tension and its variability in healthy volunteers

Baysan, M., Broere, M., Wille, M. E., Bergsma, J. E., Mik, E. G., Juffermans, N. P., Tsonaka, R., van der Bom, J. G. & Arbous, S. M., 3 Jun 2024, In: PLoS ONE. 19, 6 June, e0300602.

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1 Citation (Scopus)

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2023

Intra-renal microcirculatory alterations on non-traumatic hemorrhagic shock induced acute kidney injury in pigs

Ergin, B., van Rooij, T., Lima, A., Ince, Y., Specht, P. A., Mik, B., Aksu, U., Yavuz-Aksu, B., Kooiman, K., de Jong, N. & Ince, C., Oct 2023, In: Journal of Clinical Monitoring and Computing. 37, 5, p. 1193-1205 13 p.

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2 Citations (Scopus)

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Measuring Mitochondrial Oxygen Tension during Red Blood Cell Transfusion in Chronic Anemia Patients: A Pilot Study

Ubbink, R., Streng, L. W. J. M., Raat, N. J. H., Harms, F. A., te Boekhorst, P. A. W., Stolker, R. J. & Mik, E. G., 30 Jun 2023, In: Biomedicines. 11, 7, 1873.

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2 Citations (Scopus)

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A simulation of skin mitochondrial Po₂ in circulatory shock

Hilderink, B. N., Crane, R. F., Baysan, M., Arbous, S. M., van den Bogaard, B., Mik, E. G., Ince, C., Pillay, J. & Juffermans, N. P., May 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 134, 5, p. 1165-1176 12 p.

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5 Citations (Scopus)

Monitoring of mitochondrial oxygen tension in the operating theatre: An observational study with the novel COMET^® monitor

Harms, F. A., Streng, L. W. J. M., Wefers Bettink, M. A., de Wijs, C. J., Römers, L. H., Janse, R., Stolker, R. J. & Mik, E. G., 9 Feb 2023, In: PLoS ONE. 18, 2 February, e0278561.

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2 Citations (Scopus)

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2022

Donor variation in stored platelets: Higher metabolic rates of platelets are associated with mean platelet volume, activation and donor health

Bontekoe, I. J., van der Meer, P. F., Tanis, B. C., de Korte, D., Verhoeven, A. J., Raat, N. J. H., Specht, P. A. C., Mik, E. G. & Klei, T. R. L., Dec 2022, In: Transfusion. 62, 12, p. 2609-2620 12 p.

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5 Citations (Scopus)

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In Vivo and Ex Vivo Mitochondrial Function in COVID-19 Patients on the Intensive Care Unit

Streng, L. W. J. M., de Wijs, C. J., Raat, N. J. H., Specht, P. A. C., Sneiders, D., van der Kaaij, M., Endeman, H., Mik, E. G. & Harms, F. A., 20 Jul 2022, In: Biomedicines. 10, 7, 1746.

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12 Citations (Scopus)

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Mitochondrial Oxygenation During Cardiopulmonary Bypass: A Pilot Study

Harms, F. A., Ubbink, R., de Wijs, C. J., Ligtenberg, M. P., ter Horst, M. & Mik, E. G., 18 Jul 2022, In: Frontiers in Medicine. 9, 785734.

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8 Citations (Scopus)

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Hydroxyl Ethyl Starch (HES) Preserves Intrarenal Microcirculatory Perfusion Shown by Contrast-Enhanced Ultrasound (Ceus), and Renal Function in a Severe Hemodilution Model in Pigs

Ergin, B., Van Rooij, T., Lima, A., Ince, Y., Specht, P. A. C., Mik, E. G., Kooiman, K., De Jong, N. & Ince, C., 1 Mar 2022, In: Shock. 57, 3, p. 457-466 10 p.

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4 Citations (Scopus)

2021

Quantitative intracellular oxygen availability before and after 5-aminole-vulinic acid skin photodynamic therapy

Ubbink, R., Prens, E. P. & Mik, E. G., Dec 2021, In: Photodiagnosis and Photodynamic Therapy. 36, 102599.

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9 Citations (Scopus)

47 Downloads (Pure)

Mitochondrial oxygen monitoring with COMET: verification of calibration in man and comparison with vascular occlusion tests in healthy volunteers

Ubbink, R., Wefers Bettink, M. A., van Weteringen, W. & Mik, E. G., 21 Oct 2021, In: Journal of Clinical Monitoring and Computing. 35, 6, p. 1357-1366 10 p.

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10 Citations (Scopus)

76 Downloads (Pure)

Monitoring of mitochondrial oxygenation during perioperative blood loss

Harms, F., Brandt - Kerkhof, A. & Mik, B., 19 Jan 2021, In: BMJ Case Reports. 14, 1, e237789.

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5 Citations (Scopus)

14 Downloads (Pure)

2020

Effective Cerebral Perfusion Pressure: Does the Estimation Method Make a Difference?

Grüne, F., Mik, B., Dieters, E., Hoeks, S., Stolker, R. J., Weyland, A. & Visser, G., 2020, In: Journal of Neurosurgical Anesthesiology. 32, 4, p. 335-343 9 p.

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2 Citations (Scopus)

Mitochondrial Oxygen Monitoring During Surgical Repair of Congenital Diaphragmatic Hernia or Esophageal Atresia: A Feasibility Study

Costerus, S., Wefers Bettink, M., Tibboel, D., de Graaff, J. & Mik, B., 2020, In: Frontiers in Pediatrics. 8, 532.

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5 Citations (Scopus)

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Monitoring mitochondrial PO2: the next step

Mik, B., Balestra, G. & Harms, F., 2020, In: Current Opinion in Critical Care. 26, 3, p. 289-295 7 p.

Research output: Contribution to journal › Article › Academic

17 Citations (Scopus)

Non-invasive versus ex vivo measurement of mitochondrial function in an endotoxemia model in rat: Toward monitoring of mitochondrial therapy

Wefers Bettink, M., Harms, F., Dollée, N., Specht, P., Raat, H., Schoonderwoerd, K. & Mik, B., 2020, In: Mitochondrion. 50, p. 149-157 9 p.

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12 Citations (Scopus)

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Study protocol and pilot results of an observational cohort study evaluating effect of red blood cell transfusion on oxygenation and mitochondrial oxygen tension in critically ill patients with anaemia: The INsufficient Oxygenation in the Intensive Care Unit (INOX ICU-2) study

Baysan, M., Arbous, M., Mik, B., Juffermans, N. & Bom, J., 2020, In: BMJ Open. 10, 5, e036351.

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7 Citations (Scopus)

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2019

Comparison between pulse wave velocities measured using Complior and measured using Biopac

Velzen, M., Stolker, R. J., Loeve, A., Niehof, S. & Mik, B., 2019, In: Journal of Clinical Monitoring and Computing. 33, 2, p. 241-247 7 p.

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4 Citations (Scopus)

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Evaluation of endoscopic visible light spectroscopy: comparison with microvascular oxygen tension measurements in a porcine model

Ubbink, R., van Dijk, L., Leemreis - van Noord, D., Johannes, T., Specht, P., Bruno, M. & Mik, B., 2019, In: Journal of Translational Medicine. 17, 1, p. 65

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3 Citations (Scopus)

Measuring pulse wave velocity with a novel, simple sensor on the fingertip: a feasibility study in healthy volunteers

Velzen, M., Niehof, S., Mik, B. & Loeve, A., 2019, In: Biomedical Physics & Engineering Express. 5, 6, Unsp 065010.

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2 Citations (Scopus)

Oxygen-dependent delayed fluorescence of protoporphyrin IX measured in the stomach and duodenum during upper gastrointestinal endoscopy

van Dijk, L., Ubbink, R., Terlouw, L., Leemreis - van Noord, D., Mik, B. & Bruno, M., 2019, In: Journal of Biophotonics. 12, 10, UNSP e201900025.

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8 Citations (Scopus)

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2018

Design and Functional Testing of a Novel Blood Pulse Wave Velocity Sensor

Velzen, M., Loeve, A., Mik, B. & Niehof, S., 2018, In: Journal of Medical Devices. 12, 1, 011006.

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3 Citations (Scopus)

Dynamic Contrast-Enhanced Ultrasound Identifies Microcirculatory Alterations in Sepsis-Induced Acute Kidney Injury

Pinto Lima, A., Rooij, T., Ergin, B., Sorelli, M., Ince, Y., Specht, P., Mik, B., Bocchi, L., Kooiman, K., Jong, N. & Ince, C., 2018, In: Critical Care Medicine. 46, 8, p. 1284-1292 9 p.

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68 Citations (Scopus)

2017

A monitor for Cellular Oxygen METabolism (COMET): monitoring tissue oxygenation at the mitochondrial level

Ubbink, R., Bettink, M., Janse, R., Harms, F., Johannes, T., Munker, F. & Mik, B., 2017, In: Journal of Clinical Monitoring and Computing. 31, 6, p. 1143-1150 8 p.

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42 Citations (Scopus)

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Cutaneous Mitochondrial Po-2: A Beginning of a New Era? Reply

Römers, L., Johannes, T., Stolker, R. J. & Mik, B., 2017, In: Anesthesiology. 126, 2, p. 349-350 2 p.

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Increasing accuracy of pulse transit time measurements by automated elimination of distorted photoplethysmography waves

Velzen, M., Loeve, A., Niehof, S. & Mik, B., 2017, In: Medical & Biological Engineering & Computing. 55, 11, p. 1989-2000 12 p.

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23 Citations (Scopus)

57 Downloads (Pure)

Reducing mitochondrial bound hexokinase II mediates transition from non-injurious into injurious ischemia/reperfusion of the intact heart

Nederlof, R., Gurel-Gurevin, E., Eerbeek, O., Xie, C., Deijs, G., Konkel, M., Hu, J., Weber, N., Schumacher, C., Baartscheer, A., Mik, B., Hollmann, M., Akar, F. & Zuurbier, C., 2017, In: Journal of Physiology and Biochemistry. 73, 3, p. 323-333 11 p.

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18 Citations (Scopus)

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2016

Cutaneous Mitochondrial P o ₂, but Not Tissue Oxygen Saturation, Is an Early Indicator of the Physiologic Limit of Hemodilution in the Pig

Römers, L., Bakker, C., Dollée, N., Hoeks, S., Pinto Lima, A., Raat, H., Johannes, T., Stolker, R. J. & Mik, B., 1 Jul 2016, In: Anesthesiology. 125, 1, p. 124-132 9 p.

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32 Citations (Scopus)

Cutaneous Respirometry as Novel Technique to Monitor Mitochondrial Function: A Feasibility Study in Healthy Volunteers

Harms, F., Stolker, R. J. & Mik, B., 2016, In: PLoS One (print). 11, 7

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27 Citations (Scopus)

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Effect of heat-induced pain stimuli on pulse transit time and pulse wave amplitude in healthy volunteers

Velzen, M., Loeve, A., Kortekaas, M., Niehof, S., Mik, B. & Stolker, R. J., 2016, In: Physiological Measurement. 37, 1, p. 52-66 15 p.

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7 Citations (Scopus)

Microcirculatory and mitochondrial hypoxia in sepsis, shock, and resuscitation

Ince, C. & Mik, B., 2016, In: Journal of Applied Physiology. 120, 2, p. 226-235 10 p.

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90 Citations (Scopus)

2015

Cutaneous mitochondrial respirometry: non-invasive monitoring of mitochondrial function

Harms, F., Bodmer, S., Raat, H. & Mik, B., 2015, In: Journal of Clinical Monitoring and Computing. 29, 4, p. 509-519 11 p.

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25 Citations (Scopus)

Increased in vivo mitochondrial oxygenation with right ventricular failure induced by pulmonary arterial hypertension: mitochondrial inhibition as driver of cardiac failure?

Balestra, G., Mik, B., Eerbeek, O., Specht, P., van der Laarse, W. & Zuurbier, C., 2015, In: Respiratory Research. 16

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30 Citations (Scopus)

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In vivo assessment ofmitochondrial oxygen consumption floor

Harms, F. & Mik, B., 2015, In: Methods in Molecular Medicine. 1264, p. 219-229 11 p.

Research output: Contribution to journal › Article › Academic

Non-invasive monitoring of mitochondrial oxygenation and respiration in critical illness using a novel technique

Harms, F., Bodmer, S., Raat, H. & Mik, B., 2015, In: Critical Care. 19

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26 Citations (Scopus)

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Optimizing working space in laparoscopy: CT-measurement of the effect of neuromuscular blockade and its reversal in a porcine model

Vlot, J., Specht, P., Wijnen, R., van Rosmalen, J., Mik, B. & Bax, K., 2015, In: Surgical Endoscopy-Ultrasound and Interventional Techniques. 29, 8, p. 2210-2216 7 p.

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7 Citations (Scopus)

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Oxygenation measurement by multi-wavelength oxygen-dependent phosphorescence and delayed fluorescence: catchment depth and application in intact heart

Balestra, G., Aalders, M., Specht, P., Ince, C. & Mik, B., 2015, In: Journal of Biophotonics. 8, 8, p. 615-628 14 p.

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5 Citations (Scopus)

2013

Acute Normovolemic Hemodilution in the Pig Is Associated with Renal Tissue Edema, Impaired Renal Microvascular Oxygenation, and Functional Loss

Konrad, F., Mik, B., Bodmer, S., Ates, N., Willems, H., Klingel, K., de Geus, H., Stolker, R. J. & Johannes, T., 2013, In: Anesthesiology. 119, 2, p. 256-269 14 p.

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50 Citations (Scopus)

Cutaneous respirometry by dynamic measurement of mitochondrial oxygen tension for monitoring mitochondrial function in vivo

Harms, F., Voorbeijtel, J., Bodmer, S., Raat, H. & Mik, B., 2013, In: Mitochondrion. 13, 5, p. 507-514 8 p.

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35 Citations (Scopus)

Direct sGC Activation Bypasses NO Scavenging Reactions of Intravascular Free Oxy-Hemoglobin and Limits Vasoconstriction

Raat, H., Tabima, D., Specht, P., Tejero, J., Champion, H., Kim-Shapiro, D., Baust, J., Mik, B., Hildesheim, M., Stasch, J., Becker, E., Truebel, H. & Gladwin, M., 2013, In: Antioxidants & Redox Signaling. 19, 18, p. 2232-2243 12 p.

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24 Citations (Scopus)

Measuring Mitochondrial Oxygen Tension: From Basic Principles to Application in Humans

Mik, B., 2013, In: Anesthesia & Analgesia. 117, 4, p. 834-846 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

56 Citations (Scopus)

Pathophysiological Consequences of TAT-HKII Peptide Administration Are Independent of Impaired Vascular Function and Ensuing Ischemia

Nederlof, R., Xie, C., Eerbeek, O., Koeman, A., Milstein, D., Hollmann, M., Mik, B., Warley, A., Southworth, R., Akar, F. & Zuurbier, C., 2013, In: Circulation Research. 112, 2, p. E8-+

Research output: Contribution to journal › Article › Academic › peer-review

11 Citations (Scopus)

2012