Frank Sleutels

2024

Prenatal cell-free DNA testing of women with pregnancy-associated cancer: a retrospective cross-sectional study

Heesterbeek, C. J., Tjan-Heijnen, V. C. G., the Dutch NIPT Consortium, Heimovaara, J. H., Lenaerts, L., Lok, C., Vriens, I. J. H., Van Opstal, D., Boon, E. M. J., Sie, D., de Die-Smulders, C. E. M., Amant, F. & Macville, M. V. E., Oct 2024, In: The Lancet Regional Health - Europe. 45, 101024.

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1 Citation (Scopus)

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Early-Onset Pectus Excavatum Is More Likely to Be Part of a Genetic Variation

Billar, R., Heyman, S., Kant, S., Wijnen, R., Sleutels, F., Demirdas, S. & Schnater, J. M., 1 Aug 2024, In: European journal of pediatric surgery : official journal of Austrian Association of Pediatric Surgery ... [et al] = Zeitschrift fur Kinderchirurgie. 34, 4, p. 325-332 8 p.

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2023

Certain heterozygous variants in the kinase domain of the serine/threonine kinase NEK8 can cause an autosomal dominant form of polycystic kidney disease

Genomics England Research Consortium, Claus, L. R., Chen, C., Stallworth, J., Turner, J. L., Slaats, G. G., Hawks, A. L., Mabillard, H., Senum, S. R., Srikanth, S., Flanagan-Steet, H., Louie, R. J., Silver, J., Lerner-Ellis, J., Morel, C., Mighton, C., Sleutels, F., van Slegtenhorst, M., van Ham, T. & Brooks, A. S. & 31 others, Dorresteijn, E. M., Barakat, T. S., Dahan, K., Demoulin, N., Goffin, E. J., Olinger, E., Ambrose, J. C., Arumugam, P., Bevers, R., Bleda, M., Boardman-Pretty, F., Boustred, C. R., Brittain, H., Caulfield, M. J., Chan, G. C., Elgar, G., Fowler, T., Giess, A., Hamblin, A., Henderson, S., Hubbard, T. J. P., Jackson, R., Jones, L. J., Kasperaviciute, D., Kayikci, M., Kousathanas, A., Lahnstein, L., Leigh, S. E. A., Leong, I. U. S., Lopez, J. F. & Peters, E., Nov 2023, In: Kidney International. 104, 5, p. 995-1007 13 p.

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6 Citations (Scopus)

De novo MCM6 variants in neurodevelopmental disorders: a recognizable phenotype related to zinc binding residues

Smits, D. J., Schot, R., Popescu, C. A., Dias, K. R., Ades, L., Briere, L. C., Sweetser, D. A., Kushima, I., Aleksic, B., Khan, S., Karageorgou, V., Ordonez, N., Sleutels, F. J. G. T., van der Kaay, D. C. M., Van Mol, C., Van Esch, H., Bertoli-Avella, A. M., Roscioli, T. & Mancini, G. M. S., Jul 2023, In: Human Genetics. 142, 7, p. 949-964 16 p.

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2022

Unraveling the Genetics of Congenital Diaphragmatic Hernia: An Ongoing Challenge

Brosens, E., Peters, N. C. J., van Weelden, K. S., Bendixen, C., Brouwer, R. W. W., Sleutels, F., Bruggenwirth, H. T., van Ijcken, W. F. J., Veenma, D. C. M., Otter, S. C. M. C. D., Wijnen, R. M. H., Eggink, A. J., van Dooren, M. F., Reutter, H. M., Rottier, R. J., Schnater, J. M., Tibboel, D. & de Klein, A., 3 Feb 2022, In: Frontiers in Pediatrics. 9, 800915.

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13 Citations (Scopus)

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2021

CTCF chromatin residence time controls three-dimensional genome organization, gene expression and DNA methylation in pluripotent cells

Soochit, W., Sleutels, F., Stik, G., Bartkuhn, M., Basu, S., Hernandez, S. C., Merzouk, S., Vidal, E., Boers, R., Boers, J., van der Reijden, M., Geverts, B., van Cappellen, W. A., van den Hout, M., Ozgur, Z., van IJcken, W. F. J., Gribnau, J., Renkawitz, R., Graf, T. & Houtsmuller, A. & 3 others, Grosveld, F., Stadhouders, R. & Galjart, N., 29 Jul 2021, In: Nature Cell Biology. 23, 8, p. 881-893 13 p.

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27 Citations (Scopus)

2019

G6PD genetic variations in neonatal Hyperbilirubinemia in Indonesian Deutromalay population

Wisnumurti, D., Sribudiani, Y., Porsch, R., Maskoen, A., Rahayuningsih, S., Asni, E., Sleutels, F., van Ijcken, W., Sukadi, A. & Achmad, T., 2019, In: BMC Pediatrics. 19, 1, 506.

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8 Citations (Scopus)

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2018

Mosaic maternal 10qter deletions are associated with FRA10B expansions and may cause false-positive noninvasive prenatal screening results

van Amsterdam, K., Straver, R., van Maarle, M., Knegt, A., van Opstal, D., Sleutels, F., Smeets, D. & Sistermans, E., 2018, In: Genetics in Medicine. 20, 11, p. 1472-1476 5 p.

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14 Citations (Scopus)

Nimbus: a design-driven analyses suite for amplicon-based NGS data

Brouwer, R., Van den Hout - van Vroonhoven, M., Kockx, C., Brosens, E., Eussen, H., de Klein, A., Sleutels, F. & van Ijcken, W., 2018, In: Bioinformatics. 34, 16, p. 2732-2739 8 p.

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5 Citations (Scopus)

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UGT1A1 Genetic Variations and a Haplotype Associated with Neonatal Hyperbilirubinemia in Indonesian Population

Wisnumurti, D., Sribudiani, Y., Porsch, R., Maskoen, A., Abdulhamied, L., Rahayuningsih, S., Asni, E., Sleutels, F., Kockx, C., van Ijcken, W., Sukadi, A. & Achmad, T., 2018, In: BioMed Research International. 9425843.

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

2017

Fungal volatile compounds induce production of the secondary metabolite Sodorifen in Serratia plymuthica PRI-2C

Schmidt, R., de Jager, V., Zuhlke, D., Wolff, C., Bernhardt, J., Cankar, K., Beekwilder, J., van Ijcken, W., Sleutels, F., de Boer, W., Riedel, K. & Garbeva, P., 2017, In: Scientific Reports. 7, 862.

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102 Citations (Scopus)

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2015

Next-generation sequencing-based genome diagnostics across clinical genetics centers: implementation choices and their effects

Vrijenhoek, T., Kraaijeveld, K., Elferink, M., de Ligt, J., Kranendonk, E., Santen, G., Nijman, I., Butler, D., Claes, G., Costessi, A., Dorlijn, W., van Eyndhoven, W., Halley, D., Van den Hout - van Vroonhoven, M., van Hove, S., Johansson, L., Jongbloed, J., Kamps, R., Kockx, C. & de Koning, B. & 28 others, Kriek, M., Deprez, R., Lunstroo, H., Mannens, M., Mook, O., Nelen, M., Ploem, C., Rijnen, M., Saris, J., Sinke, R., Sistermans, E., van Slegtenhorst, M., Sleutels, F., van der Stoep, N., Tienhoven, M., Vermaat, M., Vogel, M., Waisfisz, Q., Weiss, J., van den Wijngaard, A., van Workum, W., Ijntema, H., Van der Zwaag, B., van Ijcken, W., den Dunnen, J., Veltman, J., Hennekam, R. & Cuppen, E., 2015, In: European Journal of Human Genetics. 23, 9, p. 1142-1150 9 p.

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57 Citations (Scopus)

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2012

The male germ cell gene regulator CTCFL is functionally different from CTCF and binds CTCF-like consensus sites in a nucleosome composition-dependent manner

Sleutels, F., Soochit, W., Bartkuhn, M., Heath, H., Dienstbach, S., Bergmaier, P., Franke, V., Rosa-Garrido, M., van de Nobelen, S., Caesar, L., Reijden, M., Bryne, J., van Ijcken, W., Grootegoed, A., Delgado, M., Lenhard, B., Renkawitz, R., Grosveld, F. & Galjart, N., 2012, In: Epigenetics & Chromatin. 5

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72 Citations (Scopus)

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2011

Precise BAC targeting of genetically polymorphic mouse ES cells

Barakat, S., Rentmeester, E., Sleutels, F., Grootegoed, A. & Gribnau, J., 2011, In: Nucleic Acids Research. 39, 18, e121.

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9 Citations (Scopus)

2010

CTCF regulates the local epigenetic state of ribosomal DNA repeats

van de Nobelen, S., Rosa-Garrido, M., Leers, J., Heath, H., Soochit, W., Joosen, L., Jonkers, I., Demmers, J., Reijden, M., Torrano, V., Grosveld, F., Delgado, M., Renkawitz, R., Galjart, N. & Sleutels, F., 2010, In: Epigenetics & Chromatin. 3

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79 Citations (Scopus)

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2009

Critical Role for the Transcription Regulator CCCTC-Binding Factor in the Control of Th2 Cytokine Expression

Ribeiro de Almeida, C., Heath, H., Krpic, S., Dingjan, G., Hamburg, J. P., Bergen, I., van de Nobelen, S., Sleutels, F., Grosveld, F., Galjart, N. & Hendriks, R., 2009, In: Journal of Immunology. 182, 2, p. 999-1010 12 p.

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56 Citations (Scopus)

2008

CTCF regulates cell cycle progression of alpha beta T cells in the thymus

Heath, H., Ribeiro de Almeida, C., Sleutels, F., Dingjan, G., van de Nobelen, S., Jonkers, I., Ling, K., Gribnau, J., Renkawitz, R., Grosveld, F., Hendriks, R. & Galjart, N., 2008, In: EMBO Journal. 27, 21, p. 2839-2850 12 p.

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145 Citations (Scopus)

dr. Frank Sleutels

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