Research output per year
Research output per year
Research output
- 17 Article
- 17 results
Search results
-
2024
GATA2 heterozygosity causes an epigenetic feedback mechanism resulting in myeloid and erythroid dysplasia
Gioacchino, E., Zhang, W., Koyunlar, C., Zink, J., de Looper, H., Gussinklo, K. J., Hoogenboezem, R., Bosch, D., Bindels, E., Touw, I. P. & de Pater, E., Aug 2024, In: British Journal of Haematology. 205, 2, p. 580-593 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)6 Downloads (Pure) -
2023
Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition
Koyunlar, C., Gioacchino, E., Vadgama, D., de Looper, H. W. J., Zink, J., Ter Borg, M., Hoogenboezem, R., Havermans, M., Sanders, M. A., Bindels, E., Dzierzak, E. A., Touw, I. P. & de Pater, E., 23 May 2023, In: Blood advances. 7, 10, p. 2082-2093 12 p.Research output: Contribution to journal › Article › Academic › peer-review
5 Citations (Scopus) -
Truncated CSF3 receptors induce pro-inflammatory responses in severe congenital neutropenia
Olofsen, P. A., Bosch, D. A., de Looper, H. W. J., van Strien, P. M. H., Hoogenboezem, R. M., Roovers, O., van der Velden, V. H. J., Bindels, E. M. J., De Pater, E. M. & Touw, I. P., Jan 2023, In: British Journal of Haematology. 200, 1, p. 79-86 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)142 Downloads (Pure) -
2022
MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8+ T Cell Responses
Hope, J. L., Zhao, M., Stairiker, C. J., Kiernan, C. H., Carey, A. J., Mueller, Y. M., van Meurs, M., Brouwers-Haspels, I., Otero, D. C., Bae, E. A., Faso, H. A., Maas, A., de Looper, H., Fortina, P. M., Rigoutsos, I., Bradley, L. M., Erkeland, S. J. & Katsikis, P. D., 1 Feb 2022, In: Journal of immunology (Baltimore, Md. : 1950). 208, 3, p. 603-617 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access1 Citation (Scopus) -
2021
Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish
Gioacchino, E., Koyunlar, C., Zink, J., de Looper, H., de Jong, M., Dobrzycki, T., Mahony, C. B., Hoogenboezem, R., Bosch, D., van Strien, P. M. H., van Royen, M. E., French, P. J., Bindels, E., Gussinklo, K. J., Monteiro, R., Touw, I. P. & de Pater, E., 25 Jun 2021, In: Blood advances. 5, 13, p. 2687-2700 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile20 Citations (Scopus)30 Downloads (Pure) -
PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations
Olofsen - Dieleman, P., Bosch, D., Roovers, O., Strien, P., de Looper, H., Hoogenboezem, R., Barnhoorn, S., Mastroberardino, P., Ghazvini, M., van der Velden, V., Bindels, E., De Pater, E. & Touw, I., 3 Feb 2021, In: Blood advances. 5, 3, p. 775-786 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access11 Citations (Scopus) -
2020
Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia
Olofsen, P. A., Fatrai, S., van Strien, P. M. H., Obenauer, J. C., de Looper, H. W. J., Hoogenboezem, R. M., Erpelinck-Verschueren, C. A. J., Vermeulen, M. P. W. M., Roovers, O., Haferlach, T., Jansen, J. H., Ghazvini, M., Bindels, E. M. J., Schneider, R. K., de Pater, E. M. & Touw, I. P., 25 Aug 2020, In: Cell Reports Medicine. 1, 5, p. 100074 100074.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile16 Citations (Scopus)38 Downloads (Pure) -
2016
An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation
Avellino, R., Havermans, M., Erpelinck - Verschueren, C., Sanders, M., Hoogenboezem, R., van de Werken, H., Chikhovskaya, J., van Lom, K., Strien, P., Gebhard, C., Rehli, M., Pimanda, J., Beck, D., Erkeland, S., Kuiken, T., de Looper, H., Groschel, S., Touw, I., Bindels, E. & Delwel, R., 2016, In: Blood. 127, 24, p. 2991-3003 13 p.Research output: Contribution to journal › Article › Academic › peer-review
58 Citations (Scopus) -
Ectopic miR-125a Expression Induces Long-Term Repopulating Stem Cell Capacity in Mouse and Human Hematopoietic Progenitors
Wojtowicz, E. E., Lechman, E. R., Hermans, K., Schoof, E. M., Wienholds, E., Isserlin, R., van Veelen, P., Broekhuis, M., Janssen, G., Trotman-Grant, A., Dobson, S. M., Krivdova, G., Elzinga, J., Kennedy, J., Gan, O. I., Sinha, A., Ignatchenko, V., Kislinger, T., Dethmers-Ausema, B. & Weersing, E. & 8 others, , 2016, In: Cell Stem Cell. 19, 3, p. 383-396 14 p.Research output: Contribution to journal › Article › Academic
48 Citations (Scopus) -
Genetic Variants in MicroRNAs and Their Binding Sites Are Associated with the Risk of Parkinson Disease
Ghanbari, M., Darweesh, S., de Looper, H., van Luijn, M., Hofman, B., Ikram, A., Franco Duran, O., Erkeland, S. & Dehghan, A., 2016, In: Human Mutation. 37, 3, p. 292-300 9 p.Research output: Contribution to journal › Article › Academic › peer-review
48 Citations (Scopus) -
Genome-wide identification of microRNA-related variants associated with risk of Alzheimer's disease
Ghanbari, M., Ikram, A., de Looper, H., Hofman, B., Erkeland, S., Franco Duran, O. & Dehghan, A., 2016, In: Scientific Reports. 6, 28387.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile46 Citations (Scopus)15 Downloads (Pure) -
MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice
Alemdehy, F., de Looper, H., Kavelaars, F., Sanders, M., Hoogenboezem, R., Löwenberg, B., Valk, P., Touw, I. & Erkeland, S., 2016, In: Leukemia. 30, 11, p. 2238-2241 4 p.Research output: Contribution to journal › Article › Academic › peer-review
8 Citations (Scopus) -
2015
Genetic Variations in MicroRNA-Binding Sites Affect MicroRNA-Mediated Regulation of Several Genes Associated With Cardio-metabolic Phenotypes
Ghanbari, M., Franco Duran, O., de Looper, H., Hofman, B., Erkeland, S. & Dehghan, A., 2015, In: Circulation-cardiovascular genetics. 8, 3, p. 473-486 14 p.Research output: Contribution to journal › Article › Academic
61 Citations (Scopus) -
ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation
Alemdehy, F., Haanstra, J., de Looper, H., Strien, P., Oldenampsen, J., Caljouw, Y., Sanders, M., Hoogenboezem, R., de Ru, A., Janssen, G., Smetsers, S., Bierings, M., van Veelen, P., Lindern, M., Touw, I. & Erkeland, S., 2015, In: Blood. 125, 25, p. 3937-3948 12 p.Research output: Contribution to journal › Article › Academic › peer-review
43 Citations (Scopus) -
The Association of Common Polymorphisms in miR-196a2 with Waist to Hip Ratio and miR-1908 with Serum Lipid and Glucose
Ghanbari, M., Sedaghat, S., de Looper, H., Hofman, B., Erkeland, S., Franco Duran, O. & Dehghan, A., 2015, In: Obesity. 23, 2, p. 495-503 9 p.Research output: Contribution to journal › Article › Academic › peer-review
27 Citations (Scopus) -
2012
Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice
Alemdehy, F., Boxtel, N., de Looper, H., Berge, I., Sanders, M., Cupedo, T., Touw, I. & Erkeland, S., 2012, In: Blood. 119, 20, p. 4723-4730 8 p.Research output: Contribution to journal › Article › Academic › peer-review
46 Citations (Scopus) -
2011
MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice
Meenhuis, A., van Veelen, P., de Looper, H., Boxtel, N., Berge, I., Sun, S. M., Taskesen, E., Stern, P., de Ru, A., van Adrichem, A., Demmers, J., Jongen - Lavrencic, M., Löwenberg, B., Touw, I., Sharp, P. & Erkeland, S., 2011, In: Blood. 118, 4, p. 916-925 10 p.Research output: Contribution to journal › Article › Academic › peer-review
124 Citations (Scopus)