Research output per year
Research output per year
- 1 - 50 out of 95 results
Search results
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2024
Association of plasma GFAP with elevated brain amyloid is dependent on severity of white matter lesions in an Asian cognitively impaired cohort
Chong, J. R., Chai, Y. L., Yam, A. T. Y., Hilal, S., Vrooman, H., Venketasubramanian, N., Blennow, K., Zetterberg, H., Ashton, N. J., Chen, C. P. & Lai, M. K. P., Apr 2024, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 16, 2, e12576.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)21 Downloads (Pure) -
Brain volume in infants with metopic synostosis: Less white matter volume with an accelerated growth pattern in early life
Gaillard, L., Tjaberinga, M. C., Dremmen, M. H. G., Mathijssen, I. M. J. & Vrooman, H. A., 28 Feb 2024, (E-pub ahead of print) In: Journal of Anatomy. 245, 6, p. 894-902 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)13 Downloads (Pure) -
2023
UCSQ Method Applied on 3D Photogrammetry: Non-Invasive Objective Differentiation Between Synostotic and Positional Plagiocephaly
Kronig, S. A. J., Kronig, O. D. M., Vrooman, H. A. & Van Adrichem, L. N. A., Oct 2023, In: Cleft Palate-Craniofacial Journal. 60, 10, p. 1273-1283 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)43 Downloads (Pure) -
Classification of Skull Shape Deformities Related to Craniosynostosis on 3D Photogrammetry
Kronig, S. A. J., Kronig, O. D. M., Vrooman, H. A. & Van Adrichem, L. N. A., 1 Jan 2023, In: Journal of Craniofacial Surgery. 34, 1, p. 312-317 6 p.Research output: Contribution to journal › Article › Academic › peer-review
3 Citations (Scopus) -
Diabetes and hypertension are related to amyloid-beta burden in the population-based Rotterdam Study
van Arendonk, J., Neitzel, J., Steketee, R., van Assema, D., Vrooman, H., Segbers, M., Ikram, A. & Vernooij, M., 1 Jan 2023, In: Brain. 146, 1, p. 337-348 12 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile46 Citations (Scopus)75 Downloads (Pure) -
Brain atrophy and white matter hyperintensities are independently associated with plasma neurofilament light chain in an Asian cohort of cognitively impaired patients with concomitant cerebral small vessel disease
Chong, J. R., Hilal, S., Ashton, N. J., Karikari, T. K., Reilhac, A., Vrooman, H., Schöll, M., Zetterberg, H., Blennow, K., Chen, C. P. & Lai, M. K. P., Jan 2023, In: Alzheimer's and Dementia: Diagnosis, Assessment and Disease Monitoring. 15, 1, e12396.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Citations (Scopus)55 Downloads (Pure) -
2022
Arterial Spin-Labeling Parameters and Their Associations with Risk Factors, Cerebral Small-Vessel Disease, and Etiologic Subtypes of Cognitive Impairment and Dementia
Gyanwali, B., Tan, C. S., Petr, J., Escobosa, L. L. T., Vrooman, H., Chen, C., Mutsaerts, H. J. & Hilal, S., 1 Oct 2022, In: American Journal of Neuroradiology. 43, 10, p. 1418-1423 6 p.Research output: Contribution to journal › Article › Academic › peer-review
File13 Citations (Scopus)13 Downloads (Pure) -
The Associations between Intracranial Stenosis, Brain Amyloid-beta, and Cognition in a Memory Clinic Sample
Lim, M. J. R., Tan, J., Gyanwali, B., Tanaka, T., Reilhac, A., Vrooman, H. A., Chen, C. & Hilal, S., 1 Oct 2022, In: Alzheimer Disease and Associated Disorders. 36, 4, p. 327-334 8 p.Research output: Contribution to journal › Article › Academic › peer-review
File2 Citations (Scopus)26 Downloads (Pure) -
Low Plasma Ergothioneine Predicts Cognitive and Functional Decline in an Elderly Cohort Attending Memory Clinics
Wu, L.-Y., Kan, C. N., Cheah, I. K., Chong, J. R., Xu, X., Vrooman, H., Hilal, S., Venketasubramanian, N., Chen, C. P., Halliwell, B. & Lai, M. K. P., Sept 2022, In: Antioxidants. 11, 9, 16 p., 1717.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile29 Citations (Scopus)62 Downloads (Pure) -
A Diffusion Tensor Imaging Analysis of Frontal Lobe White Matter Microstructure in Trigonocephaly Patients
de Planque, C. A., Gaillard, L., Vrooman, H. A., Li, B., Bron, E. E., van Veelen, M. L. C., Mathijssen, I. M. J. & Dremmen, M. H. G., 1 Jun 2022, In: Pediatric Neurology. 131, p. 42-48 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)47 Downloads (Pure) -
The Association between Standard Electrocardiography and Cerebral Small Vessel Disease in a Memory Clinic Study
Tanaka, T., Gyanwali, B., Villaraza, S. G., Saridin, F. N., Vrooman, H., Ihara, M., Reilhac, A., Chen, C. L. H. & Hilal, S., 5 Apr 2022, In: Journal of Alzheimer's Disease. 86, 3, p. 1093-1105 13 p.Research output: Contribution to journal › Article › Academic › peer-review
File3 Citations (Scopus)53 Downloads (Pure) -
Cerebral cortex maldevelopment in syndromic craniosynostosis
Wilson, A. T., Den Ottelander, B. K., Van Veelen, M. L. C., Dremmen, M. H. G., Persing, J. A., Vrooman, H. A., Mathijssen, I. M. J. & Tasker, R. C., Jan 2022, In: Developmental Medicine and Child Neurology. 64, 1, p. 118-124 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Citations (Scopus)76 Downloads (Pure) -
2021
Low plasma ergothioneine levels are associated with neurodegeneration and cerebrovascular disease in dementia
Wu, L. Y., Cheah, I. K., Chong, J. R., Chai, Y. L., Tan, J. Y., Hilal, S., Vrooman, H., Chen, C. P., Halliwell, B. & Lai, M. K. P., Dec 2021, In: Free Radical Biology and Medicine. 177, p. 201-211 11 p.Research output: Contribution to journal › Article › Academic › peer-review
45 Citations (Scopus) -
New method for quantification of the relative severity and (a)symmetry of isolated metopic synostosis
Kronig, O. D. M., Kronig, S. A. J., Vrooman, H. A., Veenland, J. F. & Van Adrichem, L. N. A., 1 Nov 2021, In: International Journal of Oral and Maxillofacial Surgery. 50, 11, p. 1477-1484 8 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)51 Downloads (Pure) -
Plasma P-tau181 to Aβ42 ratio is associated with brain amyloid burden and hippocampal atrophy in an Asian cohort of Alzheimer's disease patients with concomitant cerebrovascular disease
Chong, J. R., Ashton, N. J., Karikari, T. K., Tanaka, T., Saridin, F. N., Reilhac, A., Robins, E. G., Nai, Y. H., Vrooman, H., Hilal, S., Zetterberg, H., Blennow, K., Lai, M. K. P. & Chen, C. P., Oct 2021, In: Alzheimer's and Dementia. 17, 10, p. 1649-1662 14 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile49 Citations (Scopus)185 Downloads (Pure) -
Cerebral microbleeds and white matter hyperintensities are associated with cognitive decline in an asian memory clinic study
Gyanwali, B., Lui, B., Tan, C. S., Chong, E. J. Y., Vrooman, H., Chen, C. & Hilal, S., 20 Aug 2021, In: Current Alzheimer Research. 18, 5, p. 399-413 15 p.Research output: Contribution to journal › Article › Academic › peer-review
17 Citations (Scopus) -
Differences Between MR Brain Region Segmentation Methods: Impact on Single-Subject Analysis
Huizinga, W., Poot, D. H. J., Vinke, E. J., Wenzel, F., Bron, E. E., Toussaint, N., Ledig, C., Vrooman, H., Ikram, M. A., Niessen, W. J., Vernooij, M. W. & Klein, S., 30 Jul 2021, In: Frontiers in Big Data. 4, 577164.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile2 Citations (Scopus)37 Downloads (Pure) -
The Effects of Mean of Visit-to-Visit Blood Pressure on Incident Brain Vascular Lesions and Functional-Cognitive Decline
Gyanwali, B., Cai, C. X. T., Chen, C., Vrooman, H., Tan, C. S. & Hilal, S., 21 Jul 2021, In: Journal of Alzheimer's Disease. 82, 2, p. 561-573 13 p.Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
New diagnostic approach of the different types of isolated craniosynostosis
Kronig, S. A. J., Kronig, O. D. M., Vrooman, H. A., Veenland, J. F. & Van Adrichem, L. N. A., Apr 2021, In: European Journal of Pediatrics. 180, 4, p. 1211-1217 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)28 Downloads (Pure) -
Clinical Relevance of Cortical Cerebral Microinfarcts on 1.5T Magnetic Resonance Imaging in the Late-Adult Population
Hilal, S., Doolabi, A., Vrooman, H., Ikram, M. K., Ikram, M. A. & Vernooij, M. W., Mar 2021, In: Stroke. 52, 3, p. 922-930 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)36 Downloads (Pure) -
Analyzing the effect of APOE on Alzheimer's disease progression using an event-based model for stratified populations
Venkatraghavan, V., Klein, S., Fani, L., Ham, L., Vrooman, H., Ikram, K., Niessen, W. & Bron, E., 15 Feb 2021, In: NeuroImage. 227, 117646.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile14 Citations (Scopus)31 Downloads (Pure) -
White matter network damage mediates association between cerebrovascular disease and cognition
Hilal, S., Liu, S., Wong, T. Y., Vrooman, H., Cheng, C. Y., Venketasubramanian, N., Chen, C. L. H. & Zhou, J. H., 2 Feb 2021, In: Journal of Cerebral Blood Flow and Metabolism. 41, 8, p. 1858-1872 15 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access22 Citations (Scopus) -
The Impact of Strategic White Matter Hyperintensity Lesion Location on Language
Hilal, S., Biesbroek, J., Vrooman, H., Chong, E., Kuijf, H., Venketasubramanian, N., Cheng, C., Wong, T., Biessels, G. & Chen, C., Feb 2021, In: American Journal of Geriatric Psychiatry. 29, 2, p. 156-165 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile13 Citations (Scopus)113 Downloads (Pure) -
2020
Interethnic differences in neuroimaging markers and cognition in Asians: a population-based study
Wong, L. C. K., Wong, M. Y. Z., Tan, C. S., Vrooman, H., Venketasubramanian, N., Cheng, C.-Y., Chen, C. & Hilal, S., Dec 2020, In: Scientific Reports. 10, 1Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile9 Citations (Scopus)13 Downloads (Pure) -
Quantification of Severity of Unilateral Coronal Synostosis
Kronig, S. A. J., Kronig, O. D. M., Vrooman, H. A., Veenland, J. F. & Van Adrichem, L. N. A., 20 Oct 2020, In: Cleft Palate-Craniofacial Journal. 58, 7, p. 832-837 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)22 Downloads (Pure) -
Intracranial hypertension and cortical thickness in syndromic craniosynostosis
Wilson, A. T., Den Ottelander, B. K., De Goederen, R., Van Veelen, M. L. C., Dremmen, M. H. G., Persing, J. A., Vrooman, H. A. & Mathijssen, I. M. J., 1 Jul 2020, In: Developmental Medicine and Child Neurology. 62, 7, p. 799-805 7 p.Research output: Contribution to journal › Article › Academic › peer-review
Open Access15 Citations (Scopus) -
Brain amyloid ?, cerebral small vessel disease, and cognition: A memory clinic study
Saridin, F., Hilal, S., Villaraza, S., Reilhac, A., Gyanwali, B., Tanaka, T., Stephenson, M., Ng, S., Vrooman, H., Flier, W. & Chen, C. L. H., 2020, In: Neurology. 95, 21, p. e2845-e2853Research output: Contribution to journal › Article › Academic › peer-review
35 Citations (Scopus) -
Clustering of Alzheimer's and Parkinson's disease based on genetic burden of shared molecular mechanisms
Emon, M., Heinson, A., Wu, P., Domingo-Fernandez, D., Sood, M., Vrooman, H., Corvol, J., Scordis, P., Hofmann-Apitius, M. & Frohlich, H., 2020, In: Scientific Reports. 10, 1, 19097.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile12 Citations (Scopus)16 Downloads (Pure) -
Cortical cerebral microinfarcts predict cognitive decline in memory clinic patients
Hilal, S., Tan, C., van Veluw, S., Xu, X., Vrooman, H., Tan, B., Venketasubramanian, N., Biessels, G. & Chen, C., 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 1, p. 44-53 10 p.Research output: Contribution to journal › Article › Academic › peer-review
32 Citations (Scopus) -
Cortical Thickness in Crouzon-Pfeiffer Syndrome: Findings in Relation to Primary Cranial Vault Expansion
Wilson, A., de Planque, N., Yang, S., Tasker, R., van Veelen - Vincent, M. L. C., Dremmen, M., Vrooman, H. & Mathijssen, I., 2020, In: Plastic and Reconstructive Surgery-Global Open. 8, 10, e3204.Research output: Contribution to journal › Article › Academic
Open AccessFile3 Citations (Scopus)23 Downloads (Pure) -
Differences in cohort study data affect external validation of artificial intelligence models for predictive diagnostics of dementia - lessons for translation into clinical practice
Birkenbihl, C., Emon, M., Vrooman, H., Westwood, S., Lovestone, S., Hofmann-Apitius, M. & Fröhlich, H., 2020, In: EPMA Journal. 11, 3, p. 367-376 10 p.Research output: Contribution to journal › Article › Academic
Open AccessFile35 Citations (Scopus)27 Downloads (Pure) -
Improved quantification of amyloid burden and associated biomarker cut-off points: results from the first amyloid Singaporean cohort with overlapping cerebrovascular disease
Tanaka, T., Stephenson, M., Nai, Y., Khor, D., Saridin, F., Hilal, S., Villaraza, S., Gyanwali, B., Ihara, M., Vrooman, H., Weekes, A., Totman, J., Robins, E., Chen, C. & Reilhac, A., 2020, In: European Journal of Nuclear Medicine and Molecular Imaging. 47, p. 319-331 13 p.Research output: Contribution to journal › Article › Academic › peer-review
18 Citations (Scopus) -
Introducing a new method for classifying skull shape abnormalities related to craniosynostosis
Kronig, O., Kronig, S., Vrooman, H., Veenland, J. F., Jippes, M., Boen, T. & Adrichem, L., 2020, In: European Journal of Pediatrics. 179, 10, p. 1569-1577 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile21 Citations (Scopus)12 Downloads (Pure) -
MRI Markers of Mixed Pathology and Cognitive Impairment in Multiethnic Asians
Tan, C., Hilal, S., Xu, X., Vrooman, H., Cheng, C., Wong, T., Venketasubramanian, N. & Chen, C., 2020, In: Journal of Alzheimer's Disease. 73, p. 1501-1509 9 p.Research output: Contribution to journal › Article › Academic › peer-review
10 Citations (Scopus) -
Realistic simulation of virtual multi-scale, multi-modal patient trajectories using Bayesian networks and sparse auto-encoders
Sood, M., Sahay, A., Karki, R., Emon, M., Vrooman, H., Hofmann-Apitius, M. & Frohlich, H., 2020, In: Scientific Reports. 10, 1, 10971.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile10 Citations (Scopus)14 Downloads (Pure) -
2019
Cerebral Small Vessel Disease and Enlarged Perivascular Spaces-Data From Memory Clinic and Population-Based Settings
Gyanwali, B., Vrooman, H., Venketasubramanian, N., Wong, T., Cheng, C., Chen, C. & Hilal, S., 2019, In: Frontiers in Neurology. 10, 669.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile21 Citations (Scopus)12 Downloads (Pure) -
Deep learning for clustering of multivariate clinical patient trajectories with missing values
Jong, J., Emon, M., Wu, P., Karki, R., Sood, M., Godard, P., Ahmad, A., Vrooman, H., Hofmann-Apitius, M. & Frohlich, H., 2019, In: Gigascience online (online). 8, 11, giz134.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile47 Citations (Scopus)36 Downloads (Pure) -
Mixed-location cerebral microbleeds as a biomarker of neurodegeneration in a memory clinic population
Gyanwali, B., Shaik, M., Tan, C., Vrooman, H., Venketasubramanian, N., Chen, C. & Hilal, S., 2019, In: Aging-Us. 11, 22, p. 10581-10596 16 p.Research output: Contribution to journal › Article › Academic
Open AccessFile18 Citations (Scopus)14 Downloads (Pure) -
Patterns of functional connectivity in an aging population: The Rotterdam Study
Zonneveld, H., Pruim, R., Bos, D., Vrooman, H., Muetzel, R., Hofman, A., Rombouts, S., van der Lugt, A., Niessen, W., Ikram, A. & Vernooij, M., 2019, In: NeuroImage. 189, p. 432-444 13 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile127 Citations (Scopus)90 Downloads (Pure) -
2018
Automatic normative quantification of brain tissue volume to support the diagnosis of dementia: A clinical evaluation of diagnostic accuracy
Vernooij, M., Jasperse, B., Steketee, R., Koek, M., Vrooman, H., Ikram, A., Papma, J., van der Lugt, A., Smits, M. & Niessen, W., 2018, In: NeuroImage: Clinical. 20, p. 374-379 6 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile25 Citations (Scopus)20 Downloads (Pure) -
Haemoglobin, magnetic resonance imaging markers and cognition: a subsample of population-based study
Tan, B., Venketasubramanian, N., Vrooman, H., Cheng, C., Wong, T., Chen, C. & Hilal, S., 2018, In: Alzheimers Research & Therapy. 10, 114.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile17 Citations (Scopus)13 Downloads (Pure) -
Homocysteine and Cerebral Atrophy: The Epidemiology of Dementia in Singapore Study
Tan, B., Venketasubramanian, N., Vrooman, H., Cheng, C., Wong, T., Ikram, K., Chen, C. & Hilal, S., 2018, In: Journal of Alzheimers Disease. 62, 2, p. 877-885 9 p.Research output: Contribution to journal › Article › Academic › peer-review
17 Citations (Scopus) -
2017
The effect of hippocampal function, volume and connectivity on posterior cingulate cortex functioning during episodic memory fMRI in mild cognitive impairment
Papma, J., Smits, M., de Groot, M., Mattace Raso, F. U. S., van der Lugt, A., Vrooman, H., Niessen, W., Koudstaal, P., van Swieten, J. C., van der Veen, F. & Prins, N. D., Sept 2017, In: European Radiology. 27, 9, p. 3716-3724 9 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile26 Citations (Scopus)2 Downloads (Pure) -
Ankle brachial index, MRI markers and cognition: The Epidemiology of Dementia in Singapore study
Shaik, M., Venketasubramanian, N., Cheng, C., Wong, T., Vrooman, H., Ikram, K., Hilal, S. & Chen, C., 2017, In: Atherosclerosis. 263, p. 272-277 6 p.Research output: Contribution to journal › Article › Academic › peer-review
10 Citations (Scopus) -
Carotid Plaque Morphology and Ischemic Vascular Brain Disease on MRI
Bouwhuijsen, Q., Vernooij, M., Verhaaren, B., Vrooman, H., Niessen, W., Krestin, G., Ikram, A., Franco Duran, O. & van der Lugt, A., 2017, In: American Journal of Neuroradiology. 38, 9, p. 1776-1782 7 p.Research output: Contribution to journal › Article › Academic › peer-review
19 Citations (Scopus) -
Intracranial stenosis in cognitive impairment and dementia
Hilal, S., Xu, X., Ikram, M., Vrooman, H., Venketasubramanian, N. & Chen, C., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 6, p. 2262-2269 8 p.Research output: Contribution to journal › Article › Academic › peer-review
41 Citations (Scopus) -
Neuroimaging Feature Terminology: A Controlled Terminology for the Annotation of Brain Imaging Features
Iyappan, A., Younesi, E., Redolfi, A., Vrooman, H., Khanna, S., Frisoni, G., Hofmann-Apitius, M. & Alzheimer's Dis Neuroimaging, I., 2017, In: Journal of Alzheimers Disease. 59, 4, p. 1153-1169 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile11 Citations (Scopus)13 Downloads (Pure) -
2016
Cortical cerebral microinfarcts on 3T MRI A novel marker of cerebrovascular disease
Hilal, S., Sikking, E., Shaik, M., Chan, Q., van Veluw, S., Vrooman, H., Cheng, C.-Y., Sabanayagam, C., Cheung, C., Wong, T., Venketasubramanian, N., Biessels, G., Chen, C. & Ikram, K., 2016, In: Neurology. 87, 15, p. 1583-1590 8 p.Research output: Contribution to journal › Article › Academic › peer-review
109 Citations (Scopus) -
2015
IT Infrastructure to Support the Secondary Use of Routinely Acquired Clinical Imaging Data for Research
Leung, K., Lijn, F., Vrooman, H., Sturkenboom, M. & Niessen, W., 2015, In: Neuroinformatics. 13, 1, p. 65-81 17 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile6 Citations (Scopus)9 Downloads (Pure) -
MRBrainS Challenge: Online Evaluation Framework for Brain Image Segmentation in 3T MRI Scans
Mendrik, A., Vincken, K., Kuijf, H., Breeuwer, M., Bouvy, W., de Bresser, J., Alansary, A., de Bruijne, M., Carass, A., El-Baz, A., Jog, A., Katyal, R., Khan, A., Lijn, F., Mahmood, Q., Mukherjee, R., Opbroek, A., Paneri, S., Pereira, S. & Persson, M. & 10 others, , 2015, In: Computational Intelligence and Neuroscience. 2015, 813696.Research output: Contribution to journal › Article › Academic › peer-review
208 Citations (Scopus)