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Dive into the research topics where Ilse Spiekman is active. These topic labels come from the works of this person. Together they form a unique fingerprint.
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Research output
- 9 Article
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BRAFV600E-mutated central nervous system tumors benefit from treatment with dabrafenib plus trametinib: Results from the Drug Rediscovery Protocol
Haj Mohammad, S. F., Spiekman, I. A. C., Verkerk, K., Verbeek, F. A. J., Timmer, H., van Maren, M. A., Zeverijn, L. J., Geurts, B. S., Daletzakis, A., Roepman, P., Jansen, A. M. L., de Leng, W. W. J., Maas, S. L. N., de Vos, F. Y. F. L., Verheul, H. M. W., Voest, E. E. & Gelderblom, H., 2 May 2026, In: European Journal of Cancer. 238, 116674.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile7 Downloads (Pure) -
Olaparib for patients with tumors harboring alterations in homologous recombination repair genes: Results from the drug rediscovery protocol
Spiekman, I. A. C., Mehra, N., Zeverijn, L. J., Geurts, B. S., Verkerk, K., Haj Mohammad, S. F., van der Noort, V., Roepman, P., de Leng, W. W. J., Jansen, A. M. L., van de Luijtgaarden, A. C. M., van Voorthuizen, T., Buffart, T. E., Gelderblom, H., Voest, E. E. & Verheul, H. M. W., 15 Mar 2026, In: International Journal of Cancer. 158, 6, p. 1617-1627 11 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Citation (Scopus)17 Downloads (Pure) -
Checkpoint Blockade Combinations in Tumor Mutational Burden/Load-High Tumors: Insights from the Atezolizumab + Bevacizumab and Nivolumab + Ipilimumab Cohorts in the Drug Rediscovery Protocol
Verkerk, K., Haj Mohammad, S. F., Zeverijn, L. J., Geurts, B. S., Spiekman, I. A. C., Verbeek, F. A. J., Timmer, H., van Maren, M. A., van der Noort, V., Parra-Martinez, M., Roepman, P., Jansen, A. M. L., de Leng, W. W. J., Marchetti, S., Monkhorst, K., Verheul, H. M. W., Gelderblom, H. & Voest, E. E., 1 Dec 2025, In: Clinical Cancer Research : an official journal of the American Association for Cancer Research. 31, 23, p. 4964-4975 12 p.Research output: Contribution to journal › Article › Academic › peer-review
1 Citation (Scopus) -
The pathway alteration load is a pan-cancer determinant of outcome of targeted therapies: results from the Drug Rediscovery Protocol (DRUP)
Verkerk, K., Zeverijn, L. J., van de Haar, J., Roepman, P., Geurts, B. S., Spiekman, A. C., van der Noort, V., van Berge Henegouwen, J. M., Hoes, L. R., van der Wijngaart, H., Jansen, A. M. L., de Leng, W. W. J., Gelderblom, A. J., Verheul, H. M. W. & Voest, E. E., Jan 2025, In: ESMO Open. 10, 1, 104112.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Citations (Scopus)21 Downloads (Pure) -
Safety, Efficacy, and Biomarker Analysis of Crizotinib in MET-Mutated Non-Small Cell Lung Cancer-Results from the Drug Rediscovery Protocol
Verkerk, K., van der Wel, T. J. W. T., Zeverijn, L. J., Geurts, B. S., Spiekman, I. A. C., de Wit, G. F., Roepman, P., Jansen, A. M. L., van der Noort, V., Smit, E. F., Hoeben, A., Hendriks, L. E. L., van den Heuvel, M. M., Piet, B., Herder, G. J. M., Hashemi, S. M. S., Gelderblom, H., Verheul, H. M. W., Voest, E. E. & de Langen, A. J., 2 Dec 2024, In: Clinical Cancer Research. 30, 23, p. 5323-5332 10 p.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile4 Citations (Scopus)31 Downloads (Pure)