Ivo Touw

2024

GATA2 heterozygosity causes an epigenetic feedback mechanism resulting in myeloid and erythroid dysplasia

Gioacchino, E., Zhang, W., Koyunlar, C., Zink, J., de Looper, H., Gussinklo, K. J., Hoogenboezem, R., Bosch, D., Bindels, E., Touw, I. P. & de Pater, E., Aug 2024, In: British Journal of Haematology. 205, 2, p. 580-593 14 p.

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2023

RUNX1 is required in granulocyte-monocyte progenitors to attenuate inflammatory cytokine production by neutrophils

Zezulin, A. U., Yen, D., Ye, D., Howell, E. D., Bresciani, E., Diemer, J., Ren, J. G., Ahmad, M. H., Castilla, L. H., Touw, I. P., Minn, A. J., Tong, W., Liu, P. P., Tan, K., Yu, W. & Speck, N. A., 1 Jul 2023, In: Genes & Development. 37, 13-14, p. 605-620 16 p.

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3 Citations (Scopus)

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Gata2-regulated Gfi1b expression controls endothelial programming during endothelial-to-hematopoietic transition

Koyunlar, C., Gioacchino, E., Vadgama, D., de Looper, H. W. J., Zink, J., Ter Borg, M., Hoogenboezem, R., Havermans, M., Sanders, M. A., Bindels, E., Dzierzak, E. A., Touw, I. P. & de Pater, E., 23 May 2023, In: Blood advances. 7, 10, p. 2082-2093 12 p.

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2 Citations (Scopus)

A congenital CSF3R mutation in chronic neutropenia reveals a vital role for a cytokine receptor extracellular hinge motif in the response to granulocyte colony-stimulating factor

Feyen, J., Ernst, M. P. T., van der Velden, V. H. J., Valk, P. J. M., Broeders, L., Touw, I. P. & Raaijmakers, M. H. G. P., Apr 2023, In: Pediatric Blood and Cancer. 70, 4, e30039.

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The European Guidelines on Diagnosis and Management of Neutropenia in Adults and Children: A Consensus between the European Hematology Association and the EuNet-INNOCHRON COST Action

Fioredda, F., Skokowa, J., Tamary, H., Spanoudakis, M., Farruggia, P., Almeida, A., Guardo, D., Höglund, P., Newburger, P. E., Palmblad, J., Touw, I. P., Zeidler, C., Warren, A. J., Dale, D. C., Welte, K., Dufour, C. & Papadaki, H. A., Apr 2023, In: HemaSphere. 7, 4, p. E872

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10 Citations (Scopus)

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Truncated CSF3 receptors induce pro-inflammatory responses in severe congenital neutropenia

Olofsen, P. A., Bosch, D. A., de Looper, H. W. J., van Strien, P. M. H., Hoogenboezem, R. M., Roovers, O., van der Velden, V. H. J., Bindels, E. M. J., De Pater, E. M. & Touw, I. P., Jan 2023, In: British Journal of Haematology. 200, 1, p. 79-86 8 p.

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2 Citations (Scopus)

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2022

Myeloid cells promote interferon signaling-associated deterioration of the hematopoietic system

Feyen, J., Ping, Z., Chen, L., van Dijk, C., van Tienhoven, T. V. D., van Strien, P. M. H., Hoogenboezem, R. M., Wevers, M. J. W., Sanders, M. A., Touw, I. P. & Raaijmakers, M. H. G. P., 10 Dec 2022, In: Nature Communications. 13, 1, 7657.

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4 Citations (Scopus)

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Co-Occurring CSF3R W791* Germline and Somatic T618I Driver Mutations Induce Early CNL and Clonal Progression to Mixed Phenotype Acute Leukemia

Adam, F. C., Szybinski, J., Halter, J. P., Cantoni, N., Wenzel, F., Leonards, K., Brkic, S., Passweg, J. R., Touw, I., Maxson, J. E. & Meyer, S. C., 1 Feb 2022, In: Current Oncology. 29, 2, p. 805-815 11 p.

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3 Citations (Scopus)

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Congenital neutropenia: disease models guiding new treatment strategies

Touw, I. P., 1 Jan 2022, In: Current Opinion in Hematology. 29, 1, p. 27-33 7 p.

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5 Citations (Scopus)

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2021

Essential role for Gata2 in modulating lineage output from hematopoietic stem cells in zebrafish

Gioacchino, E., Koyunlar, C., Zink, J., de Looper, H., de Jong, M., Dobrzycki, T., Mahony, C. B., Hoogenboezem, R., Bosch, D., van Strien, P. M. H., van Royen, M. E., French, P. J., Bindels, E., Gussinklo, K. J., Monteiro, R., Touw, I. P. & de Pater, E., 25 Jun 2021, In: Blood advances. 5, 13, p. 2687-2700 14 p.

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18 Citations (Scopus)

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PML-controlled responses in severe congenital neutropenia with ELANE-misfolding mutations

Olofsen - Dieleman, P., Bosch, D., Roovers, O., Strien, P., de Looper, H., Hoogenboezem, R., Barnhoorn, S., Mastroberardino, P., Ghazvini, M., van der Velden, V., Bindels, E., De Pater, E. & Touw, I., 3 Feb 2021, In: Blood advances. 5, 3, p. 775-786 12 p.

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8 Citations (Scopus)

2020

Malignant Transformation Involving CXXC4 Mutations Identified in a Leukemic Progression Model of Severe Congenital Neutropenia

Olofsen, P. A., Fatrai, S., van Strien, P. M. H., Obenauer, J. C., de Looper, H. W. J., Hoogenboezem, R. M., Erpelinck-Verschueren, C. A. J., Vermeulen, M. P. W. M., Roovers, O., Haferlach, T., Jansen, J. H., Ghazvini, M., Bindels, E. M. J., Schneider, R. K., de Pater, E. M. & Touw, I. P., 25 Aug 2020, In: Cell Reports Medicine. 1, 5, p. 100074 100074.

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14 Citations (Scopus)

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Congenital and Acquired Chronic Neutropenias: Challenges, Perspectives and Implementation of the EuNet-INNOCHRON Action

Papadaki, H., Mavroudi, I., Almeida, A., Bux, J., Cichy, J., Dale, D., Donadieu, J., Hoglund, P., Karanfilski, O., Mecucci, C., Palmblad, J., Skokowa, J., Stamatopoulos, K., Touw, I., Warren, A., Welte, K., Zeidler, C. & Dufour, C., 2020, In: HemaSphere. 4, 3, e406.

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2 Citations (Scopus)

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Mutant allelic burden in acute myeloid leukaemia: Why bother?

Touw, I. & Sanders, M., 2020, In: British Journal of Haematology. 188, p. 817-818 2 p.

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2 Citations (Scopus)

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RUNX1 Mutations in the Leukemic Progression of Severe Congenital Neutropenia

Olofsen - Dieleman, P. & Touw, I., 2020, In: Molecules and Cells. 43, 2, p. 139-144 6 p.

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11 Citations (Scopus)

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Secondary CNL after SAA reveals insights in leukemic transformation of bone marrow failure syndromes

Schmied, L., Olofsen - Dieleman, P., Lundberg, P., Tzankov, A., Kleber, M., Halter, J., Uhr, M., Valk, P., Touw, I., Passweg, J. & Drexler, B., 2020, In: Blood advances. 4, 21, p. 5540-5546 7 p.

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3 Citations (Scopus)

2018

B-cell tumor development in Tet2-deficient mice

Mouly, E., Ghamlouch, H., Della-Valle, V., Scourzic, L., Quivoron, C., Roos-Weil, D., Pawlikowska, P., Saada, V., Diop, M., Lopez, C., Fontenay, M., Dessen, P., Touw, I., Mercher, T., Aoufouchi, S. & Bernard, O., 2018, In: Blood advances. 2, 6, p. 703-714 12 p.

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35 Citations (Scopus)

Recurrently affected genes in juvenile myelomonocytic leukaemia

Obenauer, J., Kavelaars, F., Sanders, M., de Vries, A. C. H., de Haas, V., Beverloo, B., de Moerloose, B., Lammens, T., Dworzak, M., Hoogenboezem, R., Valk, P., Touw, I. & Van den Heuvel - Eibrink, M., 2018, In: British Journal of Haematology. 182, 1, p. 135-138 4 p.

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5 Citations (Scopus)

2017

Classification of pediatric acute myeloid leukemia based on miRNA expression profiles

Obulkasim, A., Kuipers, J., Verboon, L., Sanders, M., Touw, I., Jongen - Lavrencic, M., Pieters, R., Klusmann, J., Zwaan, C. M., Van den Heuvel - Eibrink, M. & Fornerod, M. W. J., 2017, In: Oncotarget. 8, 20, p. 33078-33085 8 p.

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10 Citations (Scopus)

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Severe congenital neutropenias

Skokowa, J., Dale, D., Touw, I., Zeidler, C. & Welte, K., 2017, In: Nature Reviews Disease Primers. 3, 17032.

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238 Citations (Scopus)

2016

An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation

Avellino, R., Havermans, M., Erpelinck - Verschueren, C., Sanders, M., Hoogenboezem, R., van de Werken, H., Chikhovskaya, J., van Lom, K., Strien, P., Gebhard, C., Rehli, M., Pimanda, J., Beck, D., Erkeland, S., Kuiken, T., de Looper, H., Groschel, S., Touw, I., Bindels, E. & Delwel, R., 2016, In: Blood. 127, 24, p. 2991-3003 13 p.

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56 Citations (Scopus)

Lack of splice factor and cohesin complex mutations in pediatric myelodysplastic syndrome

Obenauer, J., Kavelaars, F., Sanders, M., Hoogenboezem, R., de Vries, A. C. H., Strien, P., de Haas, V., Locatelli, F., Hasle, H., Valk, P., Touw, I. & Van den Heuvel - Eibrink, M., 2016, In: Haematologica. 101, 12, p. E479-E481

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4 Citations (Scopus)

Mesenchymal Inflammation Drives Genotoxic Stress in Hematopoietic Stem Cells and Predicts Disease Evolution in Human Pre-leukemia

Zambetti, N., Ping, Z., Chen, S., Kenswil, K., Mylona, A., Sanders, M., Hoogenboezem, R., Bindels, E., Adisty, M., Strien, P., Leije, C., Westers, T., Cremers, E., Milanese, C., Mastroberardino, P., van Leeuwen, H., van der Eerden, B., Touw, I., Kuijpers, T. & Kanaar, R. & 3 others, de Loosdrecht, A., Vogl, T. & Raaijmakers, M., 2016, In: Cell Stem Cell. 19, 5, p. 613-627 15 p.

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261 Citations (Scopus)

MicroRNA-155 induces AML in combination with the loss of C/EBPA in mice

Alemdehy, F., de Looper, H., Kavelaars, F., Sanders, M., Hoogenboezem, R., Löwenberg, B., Valk, P., Touw, I. & Erkeland, S., 2016, In: Leukemia. 30, 11, p. 2238-2241 4 p.

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7 Citations (Scopus)

Myeloid conditional deletion and transgenic models reveal a threshold for the neutrophil survival factor Serpinb1

Burgener, S. S., Baumann, M., Basilico, P., Remold-O'Donnell, E., Touw, I. & Benarafa, C., 2016, In: Biological Chemistry. 397, 9, p. 897-905 9 p.

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7 Citations (Scopus)

The European Hematology Association Roadmap for European Hematology Research: a consensus document

Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Dohner, H., de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G., Schuringa, J., Andre, M., Andre-Schmutz, I., Bacigalupo, A. & Bochud, P. & 258 others, den Boer, M., Bonini, C., Camaschella, C., Cant, A., Cappellini, M., Cazzola, M., Lo Celso, C., Dimopoulos, M., Douay, L., Dzierzak, E., Einsele, H., Ferreri, A., De Franceschi, L., Gaulard, P., Gottgens, B., Greinacher, A., Gresele, P., Gribben, J., de Haan, G., Hansen, J., Hochhaus, A., Kadir, R., Kaveri, S., Kouskoff, V., Kuhne, T., Kyrle, P., Ljungman, P., Maschmeyer, G., Mendez-Ferrer, S., Milsom, M., Mummery, C., Ossenkoppele, G., Pecci, A., Peyvandi, F., Philipsen, S., Reitsma, P., Ribera, J., Risitano, A., Rivella, S., Ruf, W., Schroeder, T., Scully, M., Socie, G., Staal, F., Stanworth, S., Stauder, R., Stilgenbauer, S., Tamary, H., Theilgaard-Monch, K., Thein, S., Tilly, H., Trneny, M., Vainchenker, W., Vannucchi, A., Viscoli, C., Vrielink, H., Zaaijer, H., Zanella, A., Zolla, L., Zwaginga, J., Martinez, P., van den Akker, E., Allard, S., Anagnou, N., Andrau, J., Angelucci, E., Anstee, D., Aurer, I., Avet-Loiseau, H., Aydinok, Y., Bakchoul, T., Balduini, A., Barcellini, W., Baruch, D., Baruchel, A., Bayry, J., Bento, C., van den Berg, A., Bernardi, R., Bianchi, P., Bigas, A., Biondi, A., Bohonek, M., Bonnet, D., Borchmann, P., Borregaard, N., Braekkan, S., ten Brink, M., Brodin, E., Bullinger, L., Buske, C., Butzeck, B., Cammenga, J., Campo, E., Carbone, A., Cervantes, F., Cesaro, S., Charbord, P., Claas, F., Cohen, H., Conard, J., Coppo, P., Corrons, J., da Costa, L., Davi, F., Delwel, R., Dianzani, I., Domanovic, D., Donnelly, P., Drnovsek, T., Dreyling, M., Du, M., Durand, C., Efremov, D., Eleftheriou, A., Elion, J., Emonts, M., Engelhardt, M., Ezine, S., Falkenburg, F., Favier, R., Federico, M., Fenaux, P., Fitzgibbon, J., Flygare, J., Foa, R., Forrester, L., Galacteros, F., Garagiola, I., Gardiner, C., Garraud, O., van Geet, C., Geiger, H., Geissler, J., Germing, U., Ghevaert, C., Girelli, D., Godeau, B., Gokbuget, N., Goldschmidt, H., Goodeve, A., Graf, T., Graziadei, G., Griesshammer, M., Gruel, Y., Guilhot, F., von Gunten, S., Gyssens, I., Halter, J., Harrison, C., Harteveld, C., Hellstrom-Lindberg, E., Hermine, O., Higgs, D., Hillmen, P., Hirsch, H., Hoskin, P., Huls, G., Inati, A., Johnson, P., Kattamis, A., Kiefel, V., Kleanthous, M., Klump, H., Krause, D., Hovinga, J., Lacaud, G., Lacroix-Desmazes, S., Landman-Parker, J., LeGouill, S., Lenz, G., von Lilienfeld-Toal, M., Lindern, M., Lopez-Guillermo, A., Lopriore, E., Lozano, M., Macintyre, E., Makris, M., Martens, J., Mathas, S., Matzdorff, A., Medvinsky, A., Menendez, P., Migliaccio, A., Miharada, K., Mikulska, M., Minard, V., Montalban, C., de Montalembert, M., Montserrat, E., Morange, P., Mountford, J., Muckenthaler, M., Muller-Tidow, C., Mumford, A., Nadel, B., Navarro, J., el Nemer, W., Noizat-Pirenne, F., O'Mahony, B., Oldenburg, J., Olsson, M., Oostendorp, R., Palumbo, A., Passamonti, F., Patient, R., de Latour, R., Pflumio, F., Pierelli, L., Piga, A., Pollard, D., Raaijmakers, M., Radford, J., Rambach, R., Rao, A., Raslova, H., Rebulla, P., Rees, D., Ribrag, V., Rijneveld, A., Rinalducci, S., Robak, T., Roberts, I., Rodrigues, C., Rosendaal, F., Rosenwald, A., Rule, S., Russo, R., Saglio, G., Sanchez, M., Scharf, R., Schlenke, P., Semple, J., Sierra, J., So-Osman, C., Soria, J., Stamatopoulos, K., Stegmayr, B., Stunnenberg, H., Swinkels, D., Barata, J., Taghon, T., Taher, A., Terpos, E., Thachil, J., Tissot, J., Touw, I., Toye, A., Trappe, R., Traverse-Glehen, A., Unal, S., Vaulont, S., Viprakasit, V., Vitolo, U., van Wijk, R., Wojtowicz, A., Zeerleder, S. & Zieger, B., 2016, In: Haematologica. 101, 2, p. 115-208 94 p.

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61 Citations (Scopus)

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Transit of H2O2 across the endoplasmic reticulum membrane is not sluggish

Appenzeller-Herzog, C., Banhegyi, G., Bogeski, I., Davies, K., Delaunay-Moisan, A., Forman, H., Gorlach, A., Kietzmann, T., Laurindo, F., Margittai, E., Meyer, A., Riemer, J., Rutzler, M., Simmen, T., Sitia, R., Toledano, M. & Touw, I., 2016, In: Free Radical Biology and Medicine. 94, p. 157-160 4 p.

Research output: Contribution to journal › Article › Academic › peer-review

51 Citations (Scopus)

2015

Atypical chronic myeloid leukemia with concomitant CSF3R T618I and SETBP1 mutations unresponsive to the JAK inhibitor ruxolitinib

Ammatuna, E., Eefting, M., van Lom, K., Kavelaars, F., Valk, P. & Touw, I., 2015, In: Annals of Hematology. 94, 5, p. 879-880 2 p.

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31 Citations (Scopus)

Deficiency of the ribosome biogenesis gene Sbds in hematopoietic stem and progenitor cells causes neutropenia in mice by attenuating lineage progression in myelocytes

Zambetti, N., Bindels, E., Strien, P., Valkhof, M., Adisty, M., Hoogenboezem, R., Sanders, M., Rommens, J., Touw, I. & Raaijmakers, M., 2015, In: Haematologica. 100, 10, p. 1285-1293 9 p.

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51 Citations (Scopus)

Game of clones: the genomic evolution of severe congenital neutropenia

Touw, I., 2015, In: HEMATOLOGY-AMERICAN SOCIETY OF HEMATOLOGY EDUCATION PROGRAM. p. 1-7 7 p.

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41 Citations (Scopus)

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation

Alemdehy, F., Haanstra, J., de Looper, H., Strien, P., Oldenampsen, J., Caljouw, Y., Sanders, M., Hoogenboezem, R., de Ru, A., Janssen, G., Smetsers, S., Bierings, M., van Veelen, P., Lindern, M., Touw, I. & Erkeland, S., 2015, In: Blood. 125, 25, p. 3937-3948 12 p.

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42 Citations (Scopus)

2014

Cooperativity of RUNX1 and CSF3R mutations in severe congenital neutropenia: a unique pathway in myeloid leukemogenesis

Skokowa, J., Steinemann, D., Kuipers, J., Zeidler, C., Klimenkova, O., Klimiankou, M., Unalan, M., Kandabarau, S., Makaryan, V., Beekman, R., Behrens, K., Stocking, C., Obenauer, J., Schnittger, S., Kohlmann, A., Valkhof, M., Hoogenboezem, R., Gohring, G., Reinhardt, D. & Schlegelberger, B. & 8 others, Stanulla, M., Vandenberghe, P., Donadieu, J., Zwaan, C. M., Touw, I., Van den Heuvel - Eibrink, M., Dale, D. & Welte, K., 2014, In: Blood. 123, 14, p. 2229-2237 9 p.

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127 Citations (Scopus)

Inherited biallelic CSF3R mutations in severe congenital neutropenia

Triot, A., Jarvinen, P., Arostegui, J., Murugan, D., Kohistani, N., Diaz, J., Racek, T., Puchalka, J., Gertz, E., Schaffer, A., Kotlarz, D., Pfeifer, D., Rubio, C., Ozdemir, M., Patiroglu, T., Karakukcu, M., Codina, J., Yague, J., Touw, I. & Unal, E. & 1 others, Klein, C., 2014, In: Blood. 123, 24, p. 3811-3817 7 p.

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65 Citations (Scopus)

The JH2 domain and SH2-JH2 linker regulate JAK2 activity: A detailed kinetic analysis of wild type and V617F mutant kinase domains

Sanz Sanz, A., Niranjan, Y., Hammaren, H., Ungureanu, D., Ruijtenbeek, R., Touw, I., Silvennoinen, O. & Hilhorst, R., 2014, In: Biochimica et Biophysica Acta-Proteins and Proteomics. 1844, 10, p. 1835-1841 7 p.

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18 Citations (Scopus)

2013

Fc gamma RIIb on Myeloid Cells and Intrinsic Renal Cells Rather than B Cells Protects from Nephrotoxic Nephritis

Sharp, P., Martin-Ramirez, J., Mangsbo, S., Boross, P., Pusey, C., Touw, I., Cook, H., Verbeek, J. & Tarzi, R., 2013, In: Journal of Immunology. 190, 1, p. 340-348 9 p.

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18 Citations (Scopus)

Prevalence of a new auto-activating colony stimulating factor 3 receptor mutation (CSF3R-T595I) in acute myeloid leukemia and severe congenital neutropenia

Beekman, R., Valkhof, M., Strien, P., Valk, P. & Touw, I., 2013, In: Haematologica. 98, 5, p. E62-E63

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30 Citations (Scopus)

Scratching the surface: signaling and routing dynamics of the CSF3 receptor

Palande, K., Meenhuis, A., Jevdjovic, T. & Touw, I., 2013, In: Frontiers in Bioscience. 18, p. 91-105 15 p.

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17 Citations (Scopus)

Severe congenital neutropenia and chronic neutrophilic leukemia: an intriguing molecular connection unveiled by oncogenic mutations in CSF3R

Touw, I. & Beekman, R., 2013, In: Haematologica. 98, 10, p. 1490-1492 3 p.

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19 Citations (Scopus)

Transcriptional Reprogramming of CD11b(+)Esam(hi) Dendritic Cell Identity and Function by Loss of Runx3

Dicken, J., Mildner, A., Leshkowitz, D., Touw, I., Hantisteanu, S., Jung, S. & Groner, Y., 2013, In: PLoS One (print). 8, 10

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29 Citations (Scopus)

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2012

Loss of Ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors

Verhagen-Oldenampsen, J. H. E., Haanstra, J. R., Van Strien, P. M. H., Valkhof, M., Touw, I. P. & Von Lindern, M., 3 Jun 2012, In: Anemia. 2012, 783068.

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6 Citations (Scopus)

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Dicer1 deletion in myeloid-committed progenitors causes neutrophil dysplasia and blocks macrophage/dendritic cell development in mice

Alemdehy, F., Boxtel, N., de Looper, H., Berge, I., Sanders, M., Cupedo, T., Touw, I. & Erkeland, S., 2012, In: Blood. 119, 20, p. 4723-4730 8 p.

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46 Citations (Scopus)

IFN gamma induces monopoiesis and inhibits neutrophil development during inflammation

de Bruin, A., Libregts, S., Valkhof, M., Boon, L., Touw, I. & Nolte, M., 2012, In: Blood. 119, 6, p. 1543-1554 12 p.

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125 Citations (Scopus)

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

Horos, R., Ijspeert, H., Pospisilova, D., Sendtner, R., Andrieu-Soler, C., Taskesen, E., Nieradka, A., Cmejla, R., Sendtner, M., Touw, I. & Lindern, M., 2012, In: Blood. 119, 1, p. 262-272 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

142 Citations (Scopus)

Sequential gain of mutations in severe congenital neutropenia progressing to acute myeloid leukemia

Beekman, R., Valkhof, M., Sanders, M., Strien, P., Haanstra, J., Broeders, L., Geertsma-Kleinekoort, W., Veerman, A. J. P., Valk, P., Verhaak, R., Löwenberg, B. & Touw, I., 2012, In: Blood. 119, 22, p. 5071-5077 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

150 Citations (Scopus)

2011

The antioxidant protein peroxiredoxin 4 is epigenetically down regulated in acute promyelocytic leukemia

Palande, K., Beekman, R., van der Meeren, L., Beverloo, B., Valk, P. & Touw, I., 20 Jan 2011, In: PLoS One (print). 6, 1, e16340.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

35 Citations (Scopus)

39 Downloads (Pure)

Analysis of Jak2 Catalytic Function by Peptide Microarrays: The Role of the JH2 Domain and V617F Mutation

Sanz Sanz, A., Ungureanu, D., Pekkala, T., Ruijtenbeek, R., Touw, I., Hilhorst, R. & Silvennoinen, O., 2011, In: PLoS One (print). 6, 4

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

30 Citations (Scopus)

31 Downloads (Pure)

MiR-17/20/93/106 promote hematopoietic cell expansion by targeting sequestosome 1-regulated pathways in mice

Meenhuis, A., van Veelen, P., de Looper, H., Boxtel, N., Berge, I., Sun, S. M., Taskesen, E., Stern, P., de Ru, A., van Adrichem, A., Demmers, J., Jongen - Lavrencic, M., Löwenberg, B., Touw, I., Sharp, P. & Erkeland, S., 2011, In: Blood. 118, 4, p. 916-925 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

122 Citations (Scopus)

Peroxiredoxin-controlled G-CSF signalling at the endoplasmic reticulum-early endosome interface

Palande, K., Roovers, O., Gits, J., Verwijmeren, C., Iuchi, Y., Fujii, J., Neel, B., Karisch, R., Tavernier, J. & Touw, I., 2011, In: Journal of Cell Science. 124, 21, p. 3695-3705 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

46 Citations (Scopus)

Retroviral Integration Mutagenesis in Mice and Comparative Analysis in Human AML Identify Reduced PTP4A3 Expression as a Prognostic Indicator

Beekman, R., Valkhof, M., Erkeland, S., Taskesen, E., Rockova, V., Peeters, J., Valk, P., Löwenberg, B. & Touw, I., 2011, In: PLoS One (print). 6, 10

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

File

20 Citations (Scopus)

19 Downloads (Pure)

Scrambling for a response to G-CSF

Broxmeyer, H. & Touw, I., 2011, In: Journal of Leukocyte Biology. 90, 2, p. 215-216 2 p.

Research output: Contribution to journal › Article › Academic › peer-review

2 Citations (Scopus)

Ivo Touw

Research output

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