Johan van den Akker

2024

Presence of procoagulant peripheral blood mononuclear cells in severe COVID-19 patients relate to ventilation perfusion mismatch and precede pulmonary embolism

Dutch Covid-19 and Thrombosis Coalition (DCTC), Raadsen, M., Langerak, T., Du Toit, J., Kruip, M. J. H. A., Aynekulu Mersha, D., De Maat, M. P. M., Vermin, B., Van den Akker, J. P. C., Schmitz, K. S., Bakhtiari, K., Meijers, J. C. M., van Gorp, E. C. M., Short, K. R., Haagmans, B., de Vries, R. D., Gommers, D. A. M. P. J., Endeman, H. & Goeijenbier, M., 1 Feb 2024, In: Journal of Critical Care. 79, 154463.

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2 Citations (Scopus)

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A Systematic Review of the Pulmonary Microbiome in Patients with Acute Exacerbation COPD Requiring ICU Admission

van der Bie, S., Haaksma, M. E., Vermin, B., van Assema, H., van Gorp, E. C. M., Langerak, T., Endeman, H., Snijders, D., van den Akker, J. P. C., van Houten, M. A., van Lelyveld, S. F. L. & Goeijenbier, M., 15 Jan 2024, In: Journal of Clinical Medicine. 13, 2, 472.

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2023

Dynamics of Staphylococcus aureus in patients and the hospital environment in a tertiary care hospital in the Netherlands

van der Schoor, A. S., Voor in ’t holt, A. F., Zandijk, W. H. A., Bruno, M. J., Gommers, D., van den Akker, J. P. C., Hendriks, J. M., Severin, J. A., Klaassen, C. H. W. & Vos, M. C., 20 Dec 2023, In: Antimicrobial Resistance and Infection Control. 12, 1, p. 1-10 10 p., 148.

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1 Citation (Scopus)

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Universal screening or a universal risk assessment combined with risk-based screening for multidrug-resistant microorganisms upon admission: Comparing strategies

van der Schoor, A. S., Severin, J. A., Klaassen, C. H. W., van den Akker, J. P. C., Bruno, M. J., Hendriks, J. M., Vos, M. C. & Voor In 't Holt, A. F., 25 Jul 2023, In: PLoS ONE. 18, 7 July, e0289163.

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2 Citations (Scopus)

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Levels of Fibrinogen Variants Are Altered in Severe COVID-19

de Vries, J. J., Visser, C., van Ommen, M., Rokx, C., van Nood, E., van Gorp, E. C. M., Goeijenbier, M., van den Akker, J. P. C., Endeman, H., Rijken, D. C., Kruip, M. J. H. A., Weggeman, M., Koopman, J. & de Maat, M. P. M., Jul 2023, In: TH open : companion journal to thrombosis and haemostasis. 7, 3, p. e217-e225

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2022

The effect of 100% single-occupancy rooms on acquisition of extended-spectrum beta-lactamase-producing Enterobacterales and intra-hospital patient transfers: a prospective before-and-after study

van der Schoor, A. S., Severin, J. A., van der Weg, A. S., Strepis, N., Klaassen, C. H. W., van den Akker, J. P. C., Bruno, M. J., Hendriks, J. M., Vos, M. C. & Voor in ’t holt, A. F., Dec 2022, In: Antimicrobial Resistance and Infection Control. 11, 1, 76.

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12 Citations (Scopus)

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Altered fibrin network structure and fibrinolysis in intensive care unit patients with COVID-19, not entirely explaining the increased risk of thrombosis

de Vries, J. J., Visser, C., Geers, L., Slotman, J. A., van Kleef, N. D., Maas, C., Bax, H. I., Miedema, J. R., van Gorp, E. C. M., Goeijenbier, M., van den Akker, J. P. C., Endeman, H., Rijken, D. C., Kruip, M. J. H. A. & de Maat, M. P. M., Jun 2022, In: Journal of Thrombosis and Haemostosis. 20, 6, p. 1412-1420 9 p.

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8 Citations (Scopus)

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Interferon-α2 Auto-antibodies in Convalescent Plasma Therapy for COVID-19

Raadsen, M. P., Gharbharan, A., Jordans, C. C. E., Mykytyn, A. Z., Lamers, M. M., van den Doel, P. B., Endeman, H., van den Akker, J. P. C., GeurtsvanKessel, C. H., Koopmans, M. P. G., Rokx, C., Goeijenbier, M., van Gorp, E. C. M., Rijnders, B. J. A. & Haagmans, B. L., Feb 2022, In: Journal of Clinical Immunology. 42, 2, p. 232-239 8 p.

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36 Citations (Scopus)

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2021

Seasonal coronavirus-specific B cells with limited SARS-CoV-2 cross-reactivity dominate the IgG response in severe COVID-19

Aguilar-Bretones, M., Westerhuis, B. M., Raadsen, M. P., de Bruin, E., Chandler, F. D., Okba, N. M. A., Haagmans, B. L., Langerak, T., Endeman, H., van den Akker, J. P. C., Gommers, D. A. M. P. J., van Gorp, E. C. M., GeurtsvanKessel, C. H., de Vries, R. D., Fouchier, R. A. M., Rockx, B. H. G., Koopmans, M. P. G. & van Nierop, G. P., 1 Nov 2021, In: Journal of Clinical Investigation. 131, 21, 14 p., e150613.

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43 Citations (Web of Science)

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Increased number of positive coagulase-negative staphylococci in blood cultures is partly explained by increased use of intra-arterial catheters in patients with COVID-19

Yusuf, E., de Haan, J. E., van den Akker, J. P. C., Vogel, M., de Steenwinkel, J. E. M., Rijnders, B. J. A. & Bode, L. G. M., 1 Sept 2021, In: Journal of Hospital Infection. 115, p. 126-127 2 p.

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Aspergillus in critically ill covid‐19 patients: A scoping review

Yusuf, E., Seghers, L., Hoek, R. A. S., van den Akker, J. P. C., Bode, L. G. M. & Rijnders, B. J. A., 2 Jun 2021, In: Journal of Clinical Medicine. 10, 11, 2469.

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14 Citations (Scopus)

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High Levels of Neutrophil Extracellular Traps Persist in the Lower Respiratory Tract of Critically Ill Patients with Coronavirus Disease 2019

Ouwendijk, W. J. D., Raadsen, M. P., Van Kampen, J. J. A., Verdijk, R. M., Von Der Thusen, J. H., Guo, L., Hoek, R. A. S., Van Den Akker, J. P. C., Endeman, H., Langerak, T., Molenkamp, R., Gommers, D., Koopmans, M. P. G., Van Gorp, E. C. M., Verjans, G. M. G. M. & Haagmans, B. L., 1 May 2021, In: Journal of Infectious Diseases. 223, 9, p. 1512-1521 10 p.

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50 Citations (Scopus)

Temporal Kinetics of RNAemia and Associated Systemic Cytokines in Hospitalized COVID-19 Patients

van Riel, D., Embregts, C. W. E., Sips, G., van den Akker, J. P. C., Endeman, H., van Nood, E., Raadsen, M., Bauer, L., van Kampen, J., Molenkamp, R., Koopmans, M., van de Vijver, D. & GeurtsvanKessel, C. H., May 2021, In: mSphere. 6, 3, e00311-21.

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12 Citations (Scopus)

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Frequency of Positive Aspergillus Tests in COVID-19 Patients in Comparison to Other Patients with Pulmonary Infections Admitted to the Intensive Care Unit

Yusuf, E., Vonk, A., van den Akker, J., Bode, L., Sips, G., Rijnders, B., de Steenwinkel, J., Verkaik, N., Vogel, M., van der Eerden, M. & van Westreenen, M., 18 Feb 2021, In: Journal of Clinical Microbiology. 59, 3, e02278-20.

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16 Citations (Scopus)

Duration and key determinants of infectious virus shedding in hospitalized patients with coronavirus disease-2019 (COVID-19)

van Kampen, J., van de Vijver, D., Fraaij, P., Haagmans, B., Lamers, M., Okba, N., van den Akker, J., Endeman, R., Gommers, D., Cornelissen, J., Hoek, R. A. S., van der Eerden, M., Hesselink, D., Metselaar, H., Verbon, A., de Steenwinkel, J., Aron, G., van Gorp, E., van Boheemen, S. & Kreeft - Voermans, J. & 5 others, Boucher, C., Molenkamp, R., Koopmans, M., Geurts van Kessel, C. & Baltissen - van der Eijk, A., 11 Jan 2021, In: Nature Communications. 12, 1, 267.

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511 Citations (Scopus)

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2020

An evaluation of COVID-19 serological assays informs future diagnostics and exposure assessment

Geurts van Kessel, C., Okba, N., Iglói, Z., Bogers, S., Embregts, C., Laksono, B., Leijten, L., Rokx, C., Rijnders, B., Rahamat-Langendoen, J., Akker, J., Kampen, J., Eijk, A., van Binnendijk, R., Haagmans, B. & Koopmans, M., 2020, In: Nature Communications. 11, 1, 3436.

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275 Citations (Scopus)

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Angiotensin-converting enzyme-2 in SARS-CoV-2 infection: good or bad?

Versmissen, J., Verdonk, K., Lafeber, M., van den Akker, J., Hunfeld, N., Hoorn, E. & Danser, A., 2020, In: Journal of Hypertension. 38, 6, p. 1196-1197 2 p.

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6 Citations (Scopus)

Phenotype and kinetics of SARS-CoV-2-specific T cells in COVID-19 patients with acute respiratory distress syndrome

Weiskopf, D., Schmitz, K., Raadsen, M., Grifoni, A., Okba, N., Endeman, R., van den Akker, J., Molenkamp, R., Koopmans, M., van Gorp, E., Haagmans, B., de Swart, R., Sette, A. & de Vries, R., 2020, In: Science immunology. 5, 48, eabd2071.

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677 Citations (Scopus)

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Progressive respiratory failure in COVID-19: a hypothesis

Endeman, R., van der Zee, P., van Genderen, M., van den Akker, J. & Gommers, D., 2020, In: The Lancet Infectious Diseases. 20, 12, p. 1365

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13 Citations (Scopus)

2019

Massive diarrhoea and sepsis due to an infection with Neisseria meningitidis serogroup W

Houweling, B., Meurs, S., Versluis, J., Grewal, S., Verkaik, N. & van den Akker, J., 2019, In: Netherlands Journal of Medicine. 77, 3, p. 116-118 3 p.

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5 Citations (Scopus)

Risk indicators for acute kidney injury in cardiogenic shock

van den Akker, J., Bakker, H., Groeneveld, J. & Uil, C., 2019, In: Journal of Critical Care. 50, p. 11-16 6 p.

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26 Citations (Scopus)

2016

Obituary: Professor AB Johan Groeneveld

van den Akker, J. & Gommers, D., 2016, In: Critical Care. 20, 365.

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2013

Do we need alternatives for bicarbonate and anion gap?

van den Akker, J. & Groeneveld, J., 2013, In: Minerva Anestesiologica. 79, 10, p. 1111-1112 2 p.

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1 Citation (Scopus)

Invasive mechanical ventilation as a risk factor for acute kidney injury in the critically ill: a systematic review and meta-analysis

van den Akker, J., Egal, M. & Groeneveld, J., 2013, In: Critical Care. 17, 3

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190 Citations (Scopus)

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2012

Medical-grade honey does not reduce skin colonization at central venous catheter-insertion sites of critically ill patients: a randomized controlled trial

Kwakman, P., Muller, M., Binnekade, J., van den Akker, J., de Borgie, C., Schultz, M. & Zaat, S., 2012, In: Critical Care. 16, 5

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16 Citations (Scopus)

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Drs Johan van den Akker

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