ing. Jolanda Vaarwater

Search results

• 2022

  Genome-wide aberrant methylation in primary metastatic UM and their matched metastases

  Smit, K. N., Boers, R., Vaarwater, J., Boers, J., Brands, T., Mensink, H., Verdijk, R. M., van IJcken, W. F. J., Gribnau, J., de Klein, A. & Kilic, E., 7 Jan 2022, In: Scientific Reports. 12, 1, 42.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • metastasis 100%
  • melanoma 90%
  • methylation 73%
  • epigenetics 46%
  • genome 43%
  3 Citations (Scopus)

  2 Downloads (Pure)

• Identification of Early-Onset Metastasis in SF3B1 Mutated Uveal Melanoma

  Drabarek, W., van Riet, J., on behalf of the Rotterdam Ocular Melanoma Study Group, Nguyen, J. Q. N., Smit, K. N., van Poppelen, N. M., Jansen, R., Medico-Salsench, E., Vaarwater, J., Magielsen, F. J., Brands, T., Eussen, B., van den Bosch, T. P. P., Verdijk, R. M., Naus, N. C., Paridaens, D., de Klein, A., Brosens, E., van de Werken, H. J. G. & Kilic, E., 8 Feb 2022, In: Cancers. 14, 3, 846.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Uveal melanoma 100%
  • Neoplasm Metastasis 46%
  • Melanoma 20%
  • Spliceosomes 17%
  • Eye 15%
  1 Citation (Scopus)

  2 Downloads (Pure)
• 2021

  Molecular genetics of conjunctival melanoma and prognostic value of tert promoter mutation analysis

  van Poppelen, N. M., van Ipenburg, J. A., van den Bosch, Q., Vaarwater, J., Brands, T., Eussen, B., Magielsen, F., Dubbink, H. J., Paridaens, D., Brosens, E., Naus, N., de Klein, A., Kiliç, E. & Verdijk, R. M., 1 Jun 2021, In: International Journal of Molecular Sciences. 22, 11, 5784.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Conjunctival 100%
  • Genetics 81%
  • mutations 70%
  • Mutation 51%
  • Melanoma 50%
  5 Citations (Scopus)

  24 Downloads (Pure)

• Radiological patterns of uveal melanoma liver metastases in correlation to genetic status

  Yavuzyigitoglu, S., Tang, M. C. Y., Jansen, M., Geul, K. W., Dwarkasing, R. S., Vaarwater, J., Drabarek, W., Verdijk, R. M., Paridaens, D., Naus, N. C., Brosens, E., de Klein, A. & Kilic, E., 1 Nov 2021, In: Cancers. 13, 21, 5316.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Uveal melanoma 100%
  • Neoplasm Metastasis 46%
  • Liver 38%
  • Neoplasms 14%
  • Mutation 14%
  1 Citation (Scopus)

  22 Downloads (Pure)
• 2019

  Aberrant MicroRNA Expression and Its Implications for Uveal Melanoma Metastasis

  Smit, K., Chang, J., Derks, K., Vaarwater, J., Brands, T., Verdijk, R., Wiemer, E., Mensink, HW., Pothof, J., de Klein, A. & Kiliç, E., 2019, In: Cancers. 11, 6, E815.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  24 Citations (Scopus)

  2 Downloads (Pure)

• Multi-Modality Analysis Improves Survival Prediction in Enucleated Uveal Melanoma Patients

  Drabarek, W., Yavuzyigitoglu, S., Obulkasim, A., van Riet, J., Smit, K., van Poppelen, N., Vaarwater, J., Brands, T., Eussen, HJFMM., Verdijk, R., Naus, N., Mensink, HW., Paridaens, D., Boersma, E., van de Werken, H., Kiliç, E., de Klein, A., Keizer, ROB., van Beek, J., van Rij, C., & 3 othersBrosens, E., van Ipenburg, J. & de Bruyn, DP., 2019, In: Investigative Ophthalmology & Visual Science. 60, 10, p. 3595-3605 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  8 Citations (Scopus)

  5 Downloads (Pure)

• SRSF2 Mutations in Uveal Melanoma: A Preference for In-Frame Deletions?

  van Poppelen, N., Drabarek, W., Smit, K., Vaarwater, J., Brands, T., Paridaens, D., Kiliç, E. & de Klein, A., 2019, In: Cancers. 11, 8, 1200.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  14 Citations (Scopus)

  2 Downloads (Pure)
• 2018

  Chromosomal rearrangements in uveal melanoma: Chromothripsis

  van Poppelen, N., Yavuzyigitoglu, S., Smit, K., Vaarwater, J., Eussen, HJFMM., Brands, T., Paridaens, D., Kiliç, E. & de Klein, A., 2018, In: Genes Chromosomes & Cancer. 57, 9, p. 452-458 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  4 Citations (Scopus)

  2 Downloads (Pure)

• Combined mutation and copy-number variation detection by targeted next-generation sequencing in uveal melanoma

  Smit, K., van Poppelen, N., Vaarwater, J., Verdijk, R., van Marion, R., Kalirai, H., Coupland, S. E., Thornton, S., Farquhar, N., Dubbink, E. J., Paridaens, D., de Klein, A. & Kiliç, E., 2018, In: Modern Pathology. 31, 5, p. 763-771 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  39 Citations (Scopus)

• Genetic Background of Iris Melanomas and Iris Melanocytic Tumors of Uncertain Malignant Potential

  van Poppelen, N., Vaarwater, J., Mudhar, HS., Sisley, K., Rennie, I. G., Rundle, P., Brands, T., van den Bosch, Q., Mensink, HW., de Klein, A., Kiliç, E. & Verdijk, R., 2018, In: Ophthalmology. 125, 6, p. 904-912 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  28 Citations (Scopus)

• Re: van Poppelen et al.: Genetic background of iris melanomas and iris melanocytic tumors of uncertain malignant potential (Ophthalmology. 2018; 125: 904-912) Reply

  van Poppelen, N., Vaarwater, J., Mudhar, HS., Sisley, K., van den Bosch, Q., de Klein, A., Kiliç, E. & Verdijk, R., 2018, In: Ophthalmology. 125, 11, p. E79-E80

  Research output: Contribution to journal › Article › Academic › peer-review
• 2017

  Correlation of Gene Mutation Status with Copy Number Profile in Uveal Melanoma

  Yavuzyigitoglu, S., Drabarek, W., Smit, K., van Poppelen, N., Koopmans, A., Vaarwater, J., Brands, T., Eussen, HJFMM., Dubbink, E. J., van Riet, J., van de Werken, H., Beverloo, B., Verdijk, R., Naus, N., Paridaens, D., Kiliç, E. & de Klein, A., 2017, In: Ophthalmology. 124, 4, p. 573-575 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  19 Citations (Scopus)
• 2016

  Lipomatous Change in Uveal Melanoma: Histopathological, Immunohistochemical and Cytogenetic Analysis

  Yavuzyigitoglu, S., Kiliç, E., Vaarwater, J., de Klein, A., Paridaens, D. & Verdijk, R., 2016, In: Ocular Oncology and Pathology. 2, 3, p. 133-135 3 p.

  Research output: Contribution to journal › Article › Academic
  7 Citations (Scopus)

• Metastatic Disease in Polyploid Uveal Melanoma Patients Is Associated With BAP1 Mutations

  Yavuzyigitoglu, S., Mensink, HW., Smit, K., Vaarwater, J., Verdijk, R., Beverloo, B., Brüggenwirth, H., van Marion, R., Dubbink, E. J., Paridaens, D., Naus, N., de Klein, A. & Kiliç, E., 2016, In: Investigative Ophthalmology & Visual Science. 57, 4, p. 2232-2239 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  14 Citations (Scopus)

  2 Downloads (Pure)

• Uveal Melanomas with SF3B1 Mutations A Distinct Subclass Associated with Late-Onset Metastases

  Yavuzyigitoglu, S., Koopmans, A., Verdijk, R., Vaarwater, J., Eussen, HJFMM., van Bodegom, A., Paridaens, D., Kiliç, E. & de Klein, A., 2016, In: Ophthalmology. 123, 5, p. 1118-1128 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  142 Citations (Scopus)
• 2015

  Metastatic disease in uveal melanoma: importance of a genetic profile?

  van Beek, J., Koopmans, A., Vaarwater, J., Verdijk, R., de Klein, A., Naus, N. & Kiliç, E., 2015, In: Melanoma Research. 25, 5, p. 447-449 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)

• Risk factors associated with secondary enucleation after fractionated stereotactic radiotherapy in uveal melanoma

  van den Bosch, T., Vaarwater, J., Verdijk, R., Muller, K., Kiliç, E., Paridaens, D., de Klein, A. & Naus, N., 2015, In: Acta Ophthalmologica. 93, 6, p. 555-560 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  13 Citations (Scopus)
• 2014

  Clinical significance of immunohistochemistry for detection of BAP1 mutations in uveal melanoma

  Koopmans, A., Verdijk, R., Brouwer, R., van den Bosch, T., van den Berg, MMP., Vaarwater, J., Kockx, C., Paridaens, D., Naus, N., Nellist, M., van Ijcken, W., Kiliç, E. & de Klein, A., 2014, In: Modern Pathology. 27, 10, p. 1321-1330 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  139 Citations (Scopus)

• The Prognostic Value of Extraocular Extension in Relation to Monosomy 3 and Gain of Chromosome 8q in Uveal Melanoma

  van Beek, J., Koopmans, A., Vaarwater, J., Rooi, J., Paridaens, D., Naus, N., de Klein, A., Verdijk, R. & Kiliç, E., 2014, In: Investigative Ophthalmology & Visual Science. 55, 3, p. 1284-1291 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)
• 2013

  Chemokine Receptor CCR7 Expression Predicts Poor Outcome in Uveal Melanoma and Relates to Liver Metastasis Whereas Expression of CXCR4 Is Not of Clinical Relevance

  Bosch, T., Koopmans, A., Vaarwater, J., van den Berg, M., de Klein, A. & Verdijk, R., 2013, In: Investigative Ophthalmology & Visual Science. 54, 12, p. 7354-7361 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  27 Citations (Scopus)

• Patient survival in uveal melanoma is not affected by oncogenic mutations in GNAQ and GNA11

  Koopmans, A., Vaarwater, J., Paridaens, D., Naus, N., Kiliç, E. & de Klein, A., 2013, In: British Journal of Cancer. 109, 2, p. 493-496 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  69 Citations (Scopus)
• 2012

  Higher Percentage of FISH-Determined Monosomy 3 and 8q Amplification in Uveal Melanoma Cells relate to Poor Patient Prognosis

  Bosch, T., van Beek, J., Vaarwater, J., Verdijk, R., Naus, N., Paridaens, D., de Klein, A. & Kiliç, E., 2012, In: Investigative Ophthalmology & Visual Science. 53, 6, p. 2668-2674 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  74 Citations (Scopus)

• Multiplex ligation-dependent probe amplification equals fluorescence in-situ hybridization for the identification of patients at risk for metastatic disease in uveal melanoma

  Vaarwater, J., Bosch, T., Mensink, HW., van Kempen, CMG., Verdijk, R., Naus, N., Paridaens, D., Brüggenwirth, H., Kiliç, E. & de Klein, A., 2012, In: Melanoma Research. 22, 1, p. 30-37 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  33 Citations (Scopus)
• 2011

  Chromosomal aberrations in iris melanomas

  Mensink, HW., Vaarwater, J., de Keizer, RJW., de Wolff-Rouendaal, D., Mooy, CM., de Klein, A. & Paridaens, D., 2011, In: British Journal of Ophthalmology. 95, 3, p. 424-428 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  18 Citations (Scopus)
• 2009

  Chromosome 3 Intratumor Heterogeneity in Uveal Melanoma

  Mensink, HW., Vaarwater, J., Kiliç, E., Naus, N., Mooy, N., Luyten, GPM., Brüggenwirth, H., Paridaens, D. & de Klein, A., 2009, In: Investigative Ophthalmology & Visual Science. 50, 2, p. 500-504 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  64 Citations (Scopus)

• Oncogenic GNAQ mutations are not correlated with disease-free survival in uveal melanoma

  Bauer, J., Kiliç, E., Vaarwater, J., Bastian, BC., Garbe, C. & de Klein, A., 2009, In: British Journal of Cancer. 101, 5, p. 813-815 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  87 Citations (Scopus)
• 2008

  Molecular cytogenetic analysis of archival uveal melanoma with known clinical outcome

  Mensink, HW., Kiliç, E., Vaarwater, J., Douben, H., Paridaens, D. & de Klein, A., 2008, In: Cancer Genetics & Cytogenetics. 181, 2, p. 108-111 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  25 Citations (Scopus)

• Regional deletion and amplification on chromosome 6 in a uveal melanoma case without abnormalities on chromosomes 1p, 3 and 8

  van Gils, W., Kiliç, E., Brüggenwirth, H., Vaarwater, J., Verbiest, M., Beverloo, B., Van Til - Berg, M., Paridaens, D., Luyten, GPM. & de Klein, A., 2008, In: Melanoma Research. 18, 1, p. 10-15 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  15 Citations (Scopus)
• 2007

  Expression of APITD1 is not related to copy number changes of chromosomal region 1p36 or the prognosis of uveal melanoma

  van Gils, W., Mensink, HW., Kiliç, E., Vaarwater, J., Verbiest, M., Paridaens, D., Luyten, GPM., de Klein, A. & Brüggenwirth, H., 2007, In: Investigative Ophthalmology & Visual Science. 48, 11, p. 4919-4923 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)