Marieke von Lindern

2024

A cellular reporter system to evaluate endogenous fetal hemoglobin induction and screen for therapeutic compounds

Verheul, T. C. J., Gillemans, N., Putzker, K., Majied, R., Li, T., Vasiliou, M., Eussen, B., de Klein, A., van IJcken, W. F. J., van den Akker, E., von Lindern, M., Lewis, J., Uhrig, U., Nakamura, Y., van Dijk, T. & Philipsen, S., Aug 2024, In: HemaSphere. 8, 8, e139.

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2022

Setting the international research agenda for sarcoma together with patients and carers: first results of the Sarcoma Patient EuroNet (SPAEN) priority setting partnership

Husson, O., Drabbe, C., Schuster, K., van Kampen, P., Koops, C., Weidema, M., Davidson, R., Wartenberg, M., Artzner, E., Gonzato, O., Fernandez, N., Kasper, B., Pilgermann, K., Wilson, R., van der Graaf, W. T. A. & van Oortmerssen, G., Jun 2022, In: ESMO Open. 7, 3, 100509.

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7 Citations (Scopus)

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Epigenomic analysis of KLF1 haploinsufficiency in primary human erythroblasts

Heshusius, S., Grech, L., Gillemans, N., Brouwer, R. W. W., den Dekker, X. T., van IJcken, W. F. J., Nota, B., Felice, A. E., van Dijk, T. B., von Lindern, M., Borg, J., van den Akker, E. & Philipsen, S., 10 Jan 2022, In: Scientific Reports. 12, 1, 336.

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9 Citations (Scopus)

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2016

The European Hematology Association Roadmap for European Hematology Research: a consensus document

Engert, A., Balduini, C., Brand, A., Coiffier, B., Cordonnier, C., Dohner, H., de Wit, T., Eichinger, S., Fibbe, W., Green, T., de Haas, F., Iolascon, A., Jaffredo, T., Rodeghiero, F., Salles, G., Schuringa, J., Andre, M., Andre-Schmutz, I., Bacigalupo, A. & Bochud, P. & 258 others, den Boer, M., Bonini, C., Camaschella, C., Cant, A., Cappellini, M., Cazzola, M., Lo Celso, C., Dimopoulos, M., Douay, L., Dzierzak, E., Einsele, H., Ferreri, A., De Franceschi, L., Gaulard, P., Gottgens, B., Greinacher, A., Gresele, P., Gribben, J., de Haan, G., Hansen, J., Hochhaus, A., Kadir, R., Kaveri, S., Kouskoff, V., Kuhne, T., Kyrle, P., Ljungman, P., Maschmeyer, G., Mendez-Ferrer, S., Milsom, M., Mummery, C., Ossenkoppele, G., Pecci, A., Peyvandi, F., Philipsen, S., Reitsma, P., Ribera, J., Risitano, A., Rivella, S., Ruf, W., Schroeder, T., Scully, M., Socie, G., Staal, F., Stanworth, S., Stauder, R., Stilgenbauer, S., Tamary, H., Theilgaard-Monch, K., Thein, S., Tilly, H., Trneny, M., Vainchenker, W., Vannucchi, A., Viscoli, C., Vrielink, H., Zaaijer, H., Zanella, A., Zolla, L., Zwaginga, J., Martinez, P., van den Akker, E., Allard, S., Anagnou, N., Andrau, J., Angelucci, E., Anstee, D., Aurer, I., Avet-Loiseau, H., Aydinok, Y., Bakchoul, T., Balduini, A., Barcellini, W., Baruch, D., Baruchel, A., Bayry, J., Bento, C., van den Berg, A., Bernardi, R., Bianchi, P., Bigas, A., Biondi, A., Bohonek, M., Bonnet, D., Borchmann, P., Borregaard, N., Braekkan, S., ten Brink, M., Brodin, E., Bullinger, L., Buske, C., Butzeck, B., Cammenga, J., Campo, E., Carbone, A., Cervantes, F., Cesaro, S., Charbord, P., Claas, F., Cohen, H., Conard, J., Coppo, P., Corrons, J., da Costa, L., Davi, F., Delwel, R., Dianzani, I., Domanovic, D., Donnelly, P., Drnovsek, T., Dreyling, M., Du, M., Durand, C., Efremov, D., Eleftheriou, A., Elion, J., Emonts, M., Engelhardt, M., Ezine, S., Falkenburg, F., Favier, R., Federico, M., Fenaux, P., Fitzgibbon, J., Flygare, J., Foa, R., Forrester, L., Galacteros, F., Garagiola, I., Gardiner, C., Garraud, O., van Geet, C., Geiger, H., Geissler, J., Germing, U., Ghevaert, C., Girelli, D., Godeau, B., Gokbuget, N., Goldschmidt, H., Goodeve, A., Graf, T., Graziadei, G., Griesshammer, M., Gruel, Y., Guilhot, F., von Gunten, S., Gyssens, I., Halter, J., Harrison, C., Harteveld, C., Hellstrom-Lindberg, E., Hermine, O., Higgs, D., Hillmen, P., Hirsch, H., Hoskin, P., Huls, G., Inati, A., Johnson, P., Kattamis, A., Kiefel, V., Kleanthous, M., Klump, H., Krause, D., Hovinga, J., Lacaud, G., Lacroix-Desmazes, S., Landman-Parker, J., LeGouill, S., Lenz, G., von Lilienfeld-Toal, M., Lindern, M., Lopez-Guillermo, A., Lopriore, E., Lozano, M., Macintyre, E., Makris, M., Martens, J., Mathas, S., Matzdorff, A., Medvinsky, A., Menendez, P., Migliaccio, A., Miharada, K., Mikulska, M., Minard, V., Montalban, C., de Montalembert, M., Montserrat, E., Morange, P., Mountford, J., Muckenthaler, M., Muller-Tidow, C., Mumford, A., Nadel, B., Navarro, J., el Nemer, W., Noizat-Pirenne, F., O'Mahony, B., Oldenburg, J., Olsson, M., Oostendorp, R., Palumbo, A., Passamonti, F., Patient, R., de Latour, R., Pflumio, F., Pierelli, L., Piga, A., Pollard, D., Raaijmakers, M., Radford, J., Rambach, R., Rao, A., Raslova, H., Rebulla, P., Rees, D., Ribrag, V., Rijneveld, A., Rinalducci, S., Robak, T., Roberts, I., Rodrigues, C., Rosendaal, F., Rosenwald, A., Rule, S., Russo, R., Saglio, G., Sanchez, M., Scharf, R., Schlenke, P., Semple, J., Sierra, J., So-Osman, C., Soria, J., Stamatopoulos, K., Stegmayr, B., Stunnenberg, H., Swinkels, D., Barata, J., Taghon, T., Taher, A., Terpos, E., Thachil, J., Tissot, J., Touw, I., Toye, A., Trappe, R., Traverse-Glehen, A., Unal, S., Vaulont, S., Viprakasit, V., Vitolo, U., van Wijk, R., Wojtowicz, A., Zeerleder, S. & Zieger, B., 2016, In: Haematologica. 101, 2, p. 115-208 94 p.

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61 Citations (Scopus)

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2015

ICL-induced miR139-3p and miR199a-3p have opposite roles in hematopoietic cell expansion and leukemic transformation

Alemdehy, F., Haanstra, J., de Looper, H., Strien, P., Oldenampsen, J., Caljouw, Y., Sanders, M., Hoogenboezem, R., de Ru, A., Janssen, G., Smetsers, S., Bierings, M., van Veelen, P., Lindern, M., Touw, I. & Erkeland, S., 2015, In: Blood. 125, 25, p. 3937-3948 12 p.

Research output: Contribution to journal › Article › Academic › peer-review

42 Citations (Scopus)

2014

Transfusion-independent ?(0)-thalassemia after bone marrow transplantation failure: proposed involvement of high parental HbF and an epigenetic mechanism

Paciaroni, K., Lucarelli, G., Martelli, F., Migliaccio, A., Lindern, M., Borg, J., Gillemans, N., van Dijk, T. & Philipsen, S., 2014, In: American Journal of Blood Research. 4, 1, p. 27-32 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

7 Citations (Scopus)

2013

Hydroxyurea responsiveness in beta-thalassemic patients is determined by the stress response adaptation of erythroid progenitors and their differentiation propensity

Pourfarzad, F., Lindern, M., Azarkeivan, A., Hou, J., Kia, S., Esteghamat, F., van Ijcken, W., Philipsen, S., Najmabadi, H. & Grosveld, F., 2013, In: Haematologica. 98, 5, p. 696-704 9 p.

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47 Citations (Scopus)

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Locus-Specific Proteomics by TChP: Targeted Chromatin Purification

Pourfarzad, F., Aghajanirefah, A., Boer, E., Ten Have, S., van Dijk, T., Kheradmand Kia, S., Stadhouders, R., Thongjuea, S., Soler, E., Gillemans, N., Lindern, M., Demmers, J., Philipsen, S. & Grosveld, F., 2013, In: Cell Reports. 4, 3, p. 589-600 12 p.

Research output: Contribution to journal › Article › Academic

27 Citations (Scopus)

Red cell distribution width as predictor for mortality in critically ill patients

Meynaar, I., Knook, M., Coolen, S., Le, H., Bos, M., van der Dijs, F., Lindern, M. & Steyerberg, E., 2013, In: Netherlands Journal of Medicine. 71, 9, p. 488-493 6 p.

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57 Citations (Scopus)

2012

Loss of Ercc1 results in a time- and dose-dependent reduction of proliferating early hematopoietic progenitors

Verhagen-Oldenampsen, J. H. E., Haanstra, J. R., Van Strien, P. M. H., Valkhof, M., Touw, I. P. & Von Lindern, M., 3 Jun 2012, In: Anemia. 2012, 783068.

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6 Citations (Scopus)

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KLF10 gene expression is associated with high fetal hemoglobin levels and with response to hydroxyurea treatment in beta-hemoglobinopathy patients

Borg, J., Phylactides, M., Bartsakoulia, M., Tafrali, C., Lederer, C., Felice, A., Papachatzopoulou, A., Kourakli, A., Stavrou, E., Christou, S., Hou, J., Karkabouna, S., Lappa-Manakou, C., Ozgur, Z., van Ijcken, W., Lindern, M., Grosveld, F., Georgitsi, M., Kleanthous, M. & Philipsen, S. & 1 others, Patrinos, G., 2012, In: Pharmacogenomics. 13, 13, p. 1487-1500 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

39 Citations (Scopus)

Molecular mechanisms of pathology and treatment in Diamond Blackfan Anaemia

Horos, R. & Lindern, M., 2012, In: British Journal of Haematology. 159, 5, p. 514-527 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

51 Citations (Scopus)

Ribosomal deficiencies in Diamond-Blackfan anemia impair translation of transcripts essential for differentiation of murine and human erythroblasts

Horos, R., Ijspeert, H., Pospisilova, D., Sendtner, R., Andrieu-Soler, C., Taskesen, E., Nieradka, A., Cmejla, R., Sendtner, M., Touw, I. & Lindern, M., 2012, In: Blood. 119, 1, p. 262-272 11 p.

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143 Citations (Scopus)

2011

The DNA binding factor Hmg20b is a repressor of erythroid differentiation

Esteghamat, F., van Dijk, T., Braun, H., Dekker, S., Linden, R., Hou, J., Fanis, P., Demmers, J., van Ijcken, W., Ozgur, Z., Horos, R., Pourfarzad, F., Lindern, M. & Philipsen, S., 2011, In: Haematologica. 96, 9, p. 1252-1260 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

2010

Fetal globin expression is regulated by Friend of Prmt1

van Dijk, T., Gillemans, N., Pourfarzad, F., van Lom, K., Lindern, M., Grosveld, F. & Philipsen, S., 2010, In: Blood. 116, 20, p. 4349-4352 4 p.

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37 Citations (Scopus)

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

Borg, J., Papadopoulos, P., Georgitsi, M., Gutierrez Gutierrez, L., Grech, G., Fanis, P., Phylactides, M., Verkerk, A., van der Spek, P., Scerri, C., Cassar, W., Galdies, R., van Ijcken, W., Ozgur, Z., Gillemans, N., Hou, J., Bugeja, M., Grosveld, F., Lindern, M. & Felice, A. & 2 others, Patrinos, G. & Philipsen, S., 2010, In: Nature Genetics. 42, 9, p. 801-U100

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328 Citations (Scopus)

The miR-144/451 locus is required for erythroid homeostasis

Rasmussen, K., Simmini, S., Abreu-Goodger, C., Bartonicek, N., Di Giacomo, M., Bilbao-Cortes, D., Horos, R., Lindern, M., Enright, A. & O'Carroll, D., 2010, In: Journal of Experimental Medicine. 207, 7, p. 1351-1358 8 p.

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265 Citations (Scopus)

2009

EZH2-dependent chromatin looping controls INK4a and INK4b, but not ARF, during human progenitor cell differentiation and cellular senescence

Kheradmand Kia, S., Solaimani Kartalaei, P., Farahbakhshian, E., Pourfarzad, F., Lindern, M. & Verrijzer, P., 2009, In: Epigenetics & Chromatin. 2, p. 16

Research output: Contribution to journal › Article › Academic › peer-review

2008

DNA methylation-independent loss of RARA gene expression in acute myeloid leukemia

Glasow, A., Barrett, A., Petrie, K., Gupta, R., Boix-Chornet, M., Zhou, D., Grimwade, D., Gallagher, R., Lindern, M., Waxman, S., Enver, T., Hildebrandt, G. & Zelent, A., 2008, In: Blood. 111, 4, p. 2374-2377 4 p.

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33 Citations (Scopus)

Igbp1 is part of a positive feedback loop in stem cell factor-dependent, selective mRNA translation initiation inhibiting erythroid differentiation

Grech, G., Blazquez-Domingo, M., Kolbus, A., Bakker, W., Mullner, E., Beug, H. & Lindern, M., 2008, In: Blood. 112, 7, p. 2750-2760 11 p.

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35 Citations (Scopus)

Tissue-specific splicing factor gene expression signatures

Grosso, A., Gomes, A., Barbosa-Morais, N., Caldeira, S., Thorne, N., Grech, G., Lindern, M. & Carmo-Fonseca, M., 2008, In: Nucleic Acids Research. 36, 15, p. 4823-4832 10 p.

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137 Citations (Scopus)

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2007

Beta-globin active chromatin hub formation in differentiating erythroid cells and in p45 NF-E2 knock-out mice

Kooren, J., Palstra, R.-J., Klous, P., Splinter, E., Lindern, M., Grosveld, F. & de Laat, W., 2007, In: Journal of Biological Chemistry. 282, 22, p. 16544-16552 9 p.

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67 Citations (Scopus)

Differential regulation of Foxo3a target genes in erythropoiesis

Bakker, W., van Dijk, T., Parren-van Amelsvoort, M., Kolbus, A., Yamamoto, K., Steinlein, P., Verhaak, R., Mak, T., Beug, H., Löwenberg, B. & Lindern, M., 2007, In: Molecular and Cellular Biology. 27, 10, p. 3839-3854 16 p.

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67 Citations (Scopus)

Dynamic regulation of Gata factor levels is more important than their identity

Ferreira, R., Wai, A., Shimizu, R., Gillemans, N., Rottier, R., Lindern, M., Ohneda, K., Grosveld, F., Yamamoto, M. & Philipsen, S., 2007, In: Blood. 109, 12, p. 5481-5490 10 p.

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39 Citations (Scopus)

2006

Adaptive stress response in segmental progeria resembles long-lived dwarfism and calorie restriction in mice

van de Ven, H., Andressoo, J., Holcomb, V., Lindern, M., Jong, W., de Zeeuw, C., Suh, Y., Hasty, P., Hoeijmakers, J., van der Horst, B. & Mitchell, J., 2006, In: PLoS Genetics (print). 2, p. 192-192 1 p.

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50 Citations (Scopus)

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Cell-cycle control in erythropoiesis

Lindern, M., 2006, In: Blood. 108, 3, p. 781-782 2 p.

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9 Citations (Scopus)

2005

Retinoids and myelomonocytic growth factors cooperatively activate RARA and induce human myeloid leukemia cell differentiation via MAP kinase pathways

Glasow, A., Prodromou, N., Xu, K., Lindern, M. & Zelent, A., 2005, In: Blood. 105, 1, p. 341-349 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

62 Citations (Scopus)

The erythroid phenotype of EKLF-null mice: Defects in hemoglobin metabolism and membrane stability

Drissen, R., Lindern, M., Kolbus, A., Driegen, S., Steinlein, P., Beug, H., Grosveld, F. & Philipsen, S., 2005, In: Molecular and Cellular Biology. 25, 12, p. 5205-5214 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

140 Citations (Scopus)

Translation initiation factor 4E inhibits differentiation of erythroid progenitors

Blazquez-Domingo, M., Grech, G. & Lindern, M., 2005, In: Molecular and Cellular Biology. 25, 19, p. 8496-8506 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

2004

Btk is required for an efficient response to erythropoietin and for SCF-controlled protection against trail in erythroid progenitors

Schmidt, U., van den Akker, E., Parren- van Amelsvoort, M., Litos, G., de Bruijn, M., Gutierrez Gutierrez, L., Hendriks, R., Ellmeier, W., Löwenberg, B., Beug, H. & Lindern, M., 2004, In: Journal of Experimental Medicine. 199, p. 785-795 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

45 Citations (Scopus)

FOXO3a regulates erythroid differentiation and induces BTG1, an activator of arginine methyl transferase 1

Bakker, W., Blazquez Domingo, M., Kolbus, A., Besooijen, J., Steinlein, P., Beug, H., Coffer, P., Löwenberg, B., Lindern, M. & van Dijk, T., 2004, In: Journal of Cell Biology. 164, p. 175-184 10 p.

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144 Citations (Scopus)

The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity

van den Akker, E., van Dijk, T., Schmidt, U., Felida, L., Beug, H., Löwenberg, B. & Lindern, M., 2004, In: Biological Chemistry. 385, p. 409-413 5 p.

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38 Citations (Scopus)

Translational control of Putative protooncogene Nm23M2 by cytokines via phosphoinositide-3-kinase signaling

Joosten, M., Blazquez Domingo, M., Lindeboom, F., Boulmé, F., Beijen, A., Habermann, B., Löwenberg, B., Beug, H., Müllner, E., Delwel, R. & Lindern, M., 2004, In: Journal of Biological Chemistry. 279, 37, p. 38169-38176 8 p.

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21 Citations (Scopus)

Tyrosine kinase receptor RON functions downstream of the erythropoietin receptor to induce expansion of erythroid progenitors

van den Akker, E., van Dijk, T., Parren- van Amelsvoort, M., Grossmann, K., Schaeper, U., Toney-Earley, K., Waltz, S., Löwenberg, B. & Lindern, M., 2004, In: Blood. 103, p. 4457-4466 10 p.

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33 Citations (Scopus)

2003

Cooperative signaling between cytokine receptors and the glucocorticoid receptor in the expansion of erythroid progenitors: molecular analysis by expression profiling

Kolbus, A., Blazquez Domingo, M., Carotta, S., Bakker, W., Luedemann, S., Lindern, M., Steinlein, P. & Beug, H., 2003, In: Blood. 102, p. 3136-3146 11 p.

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87 Citations (Scopus)

Stem cell factor receptor (c-KIT) codon 816 mutations predict development of bilateral testicular germ cell tumors

Looijenga, L., Leeuw, H., Oorschot, M., van Gurp, R., Stoop, H., Gillis, A., de Gouveia Brazao, C., Weber, R., Kirkels, W., van Dijk, T., Lindern, M., Valk, P., Lajos, G., Olah, E., Nesland, J., Fossa, S. & Oosterhuis, W., 2003, In: Cancer Research. 63, p. 7674-7678 5 p.

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168 Citations (Scopus)

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2002

MLL-ENL cooperates with SCF to transform primary avian multipotent cells

Schulte, C., Lindern, M., Steinlein, P., Beug, H. & Wiedemann, L., 2002, In: EMBO Journal. 21, 6, p. 4297-4306 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Stochastic patterns in globin gene expression are established prior to transcriptional activation and are clonally inherited

de Krom, M., Corput, M., Lindern, M., Grosveld, F. & Strouboulis, I., 2002, In: Molecular Cell. 9, p. 1319-1326 8 p.

Research output: Contribution to journal › Article › Academic

50 Citations (Scopus)

2001

Leukemic transformation of normal murine erythroid progenitors: v- and c-ErbB act through signaling pathways activated by the EpoR and c-Kit in stress erythropoiesis

Lindern, M., Deiner, E., Dolznig, H., Parren- van Amelsvoort, M., Hayman, M., Mullner, E. & Beug, H., 2001, In: Oncogene. 20, p. 3651-3664 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

90 Citations (Scopus)

2000

Enhancement of erythropoietin-stimulated cell proliferation by Anandamide correlates with increased activation of the mitogen-activated protein kinases ERK1 and ERK2

Valk, P., Verbakel, S., Lindern, M., Löwenberg, B. & Delwel, R., 2000, In: Hematology Journal. 1, p. 254-263 10 p.

Research output: Contribution to journal › Article › Academic

12 Citations (Scopus)

Protein kinase C alpha controls erythropoietin receptor signaling

Lindern, M., Parren-van Amelsvoort, M., van Dijk, T., Deiner, E., van den Akker, E., van Emst- de Vries, S., Willems, P., Beug, H. & Löwenberg, B., 2000, In: Journal of Biological Chemistry. 275, 44, p. 34719-34727 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

67 Citations (Scopus)

Stem cell factor induces phosphatidylinositol 3'-kinase-dependent Lyn/Tec/Dok-1 complex formation in hematopoietic cells

van Dijk, T., van den Akker, E., Parren-van Amelsvoort, M., Mano, H., Löwenberg, B. & Lindern, M., 2000, In: Blood. 96, p. 3406-3413 8 p.

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88 Citations (Scopus)

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1999

A novel way to induce erythroid progenitor self renewal: cooperation of c-Kit with the erythropoietin receptor

Wessely, O., Bauer, A., Quang, C., Deiner, E., Lindern, M., Mellitzer, G., Steinlein, P., Ghysdael, J. & Beug, H., 1999, In: Biological Chemistry. 380, p. 187-202 16 p.

Research output: Contribution to journal › Article › Academic › peer-review

33 Citations (Scopus)

The glucocorticoid receptor cooperates with the erythropoietin receptor and c-kit to enhance and sustain proliferation of erythroid progenitors in vitro

Lindern, M., Zauner, W., Mellitzer, G., Steinlein, P., Fritsch, G., Huber, K., Löwenberg, B. & Beug, H., 1999, In: Blood. 94, 2, p. 550-559 10 p.

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218 Citations (Scopus)

53 Downloads (Pure)

The use of in vitro expanded erythroid cells in a model system for the isolation of fetal cells from maternal blood

Jansen, M., Lindern, M., Beug, H., Brandenburg, H., Wildschut, H., Wladimiroff, J. & Veld, P., 1999, In: Prenatal Diagnosis. 19, p. 323-329 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

25 Citations (Scopus)

1998

Erythroid Krüppel-like Factor (EKLF) is active in primitive and definitive erythroid cells and is required for the function of 5'HS3 of the ß-globin locus control region.

Tewari, R., Gillemans, N., Wijgerde, M., Nuez, B., Lindern, M., Grosveld, F. & Philipsen, S., 1998, In: EMBO Journal. 17, 8, p. 2334-2341 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

72 Citations (Scopus)

Leukemic transformation by the v-ErbA oncoprotein entails constitutive binding to and repression of an erythroid enhancer in vivo

Ciana, P., Braliou, G., Demay, F., Lindern, M., Barettino, D., Beug, H. & Stunnenberg, H., 1998, In: EMBO Journal. 17, 24, p. 7382-7394 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

32 Citations (Scopus)

The transactivation Domain AF-2 but not the DNA-binding domain of the estrogen receptor is required to inhibit differentiation of avian erythroid progenitors

Lindern, M., Boer, L., Wessely, O., Parker, M. & Beug, H., 1998, In: Molecular Endocrinology. 12, p. 263-277 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

12 Citations (Scopus)

1995

Relocation of the carboxyterminal part of CAN from the nuclear envelope to the nucleus as a result of leukemia-specific chromosome rearrangements

Fornerod, M., Boer, J., Van Baal, S., Jaeglé, M., Von Lindern, M., Murti, K. G., Davis, D., Bonten, J., Buijs, A. & Grosveld, G., 4 May 1995, In: Oncogene. 10, 9, p. 1739-1748 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

145 Citations (Scopus)

1992

The translocation (6;9), associated with a specific subtype of acute myeloid leukemia, results in the fusion of two genes, dek and can, and the expression of a chimeric, leukemia-Specific dek-can mRNA

Von Lindern, M., Fornerod, M., Van Baal, S., Jaegle, M., De Wit, T., Buijs, A. & Grosveld, G., Apr 1992, In: Molecular and Cellular Biology. 12, 4, p. 1687-1697 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

353 Citations (Scopus)

Marieke von Lindern

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