Marjan van Meurs

Mueller, Y. M., Schrama, T. J., Ruijten, R., Schreurs, M. W. J., Grashof, D. G. B., van de Werken, H. J. G., Lasinio, G. J., Álvarez-Sierra, D., Kiernan, C. H., Castro Eiro, M. D., van Meurs, M., Brouwers-Haspels, I., Zhao, M., Li, L., de Wit, H., Ouzounis, C. A., Wilmsen, M. E. P., Alofs, T. M., Laport, D. A. & van Wees, T. & 8 others, Kraker, G., Jaimes, M. C., Van Bockstael, S., Hernández-González, M., Rokx, C., Rijnders, B. J. A., Pujol-Borrell, R. & Katsikis, P. D., 17 Feb 2022, In: Nature Communications. 13, 1, 915.

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38 Citations (Scopus)

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MicroRNA-139 Expression Is Dispensable for the Generation of Influenza-Specific CD8⁺ T Cell Responses

Hope, J. L., Zhao, M., Stairiker, C. J., Kiernan, C. H., Carey, A. J., Mueller, Y. M., van Meurs, M., Brouwers-Haspels, I., Otero, D. C., Bae, E. A., Faso, H. A., Maas, A., de Looper, H., Fortina, P. M., Rigoutsos, I., Bradley, L. M., Erkeland, S. J. & Katsikis, P. D., 1 Feb 2022, In: Journal of immunology (Baltimore, Md. : 1950). 208, 3, p. 603-617 15 p.

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1 Citation (Scopus)

2020

Heatr9is an infection responsive gene that affects cytokine production in alveolar epithelial cells

Stairiker, C., van Meurs, M., Gonzalez Leon, L., Brouwers - Haspels, I., Rijsbergen, L., Müller, Y. & Katsikis, P., 2020, In: PLoS One (print). 15, 7, e0236195.

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3 Citations (Scopus)

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Microenvironment-Dependent Gradient of CTL Exhaustion in the AE17sOVA Murine Mesothelioma Tumor Model

Hope, J., Spantidea, P., Van der Wel - Kiernan, C., Stairiker, C., Rijsbergen, L., van Meurs, M., Brouwers - Haspels, I., Müller, Y., Nelson, D., Bradley, L., Aerts, J. & Katsikis, P., 2020, In: Frontiers in Immunology. 10, 3074.

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7 Citations (Scopus)

25 Downloads (Pure)

Rapidin vitrogeneration of bona fide exhausted CD8+T cells is accompanied byTcf7 promotor methylation

Zhao, M., Van der Wel - Kiernan, C., Stairiker, C., Hope, J., Gonzalez Leon, L., van Meurs, M., Brouwers - Haspels, I., Boers, R., Boers, J., Gribnau, J., van Ijcken, W., Bindels, E., Hoogenboezem, R., Erkeland, S., Müller, Y. & Katsikis, P., 2020, In: PLoS Pathogens (print). 16, 6, e1008555.

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35 Citations (Scopus)

32 Downloads (Pure)

2017

The Transcription Factor T-Bet Is Regulated by MicroRNA-155 in Murine Anti-Viral CD8+T Cells via SHIP-1

Hope, J., Stairiker, C., Spantidea, P., Gracias, D., Carey, A., Fike, A., van Meurs, M., Brouwers - Haspels, I., Rijsbergen, L., Fraietta, J., Müller, Y., Klop, R., Stelekati, E., Wherry, E., Erkeland, S. & Katsikis, P., 2017, In: Frontiers in Immunology. 8, 1696.

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26 Citations (Scopus)

21 Downloads (Pure)

2016

Elevated Expression of the Cerebrospinal Fluid Disease Markers Chromogranin A and Clusterin in Astrocytes of Multiple Sclerosis White Matter Lesions

van Luijn, M., van Meurs, M., Stoop, M., Verbraak, E., Wierenga - Wolf, A., Melief, M.-J., Kreft, K., Verdijk, R., 't Hart, B., Luider, T., Laman, J. & Hintzen, R., 2016, In: Journal of Neuropathology and Experimental Neurology. 75, 1, p. 86-98 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Scopus)

Pro-inflammatory cytokines in cryptoglandular anal fistulas

Onkelen, R., Gosselink, M., van Meurs, M., Melief, M.-J., Schouten, W. R. & Laman, J., 2016, In: Techniques in Coloproctology. 20, 9, p. 619-625 7 p.

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29 Citations (Scopus)

18 Downloads (Pure)

Rotarod motor performance and advanced spinal cord lesion image analysis refine assessment of neurodegeneration in experimental autoimmune encephalomyelitis

Berg, R., Laman, J., van Meurs, M., Hintzen, R. & Hoogenraad, C., 2016, In: Journal of Neuroscience Methods. 262, p. 66-76 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

2015

Multiple sclerosis-associated CLEC16A controls HLA class II expression via late endosome biogenesis

van Luijn, M., Kreft, K., Jongsma, M., Mes, S., Wierenga - Wolf, A., van Meurs, M., Melief, M.-J., van der Kant, R., Janssen, L., Janssen, H., Tan, R., Priatel, J., Neefjes, J., Laman, J. & Hintzen, R., 2015, In: Brain. 138, p. 1531-1547 17 p.

Research output: Contribution to journal › Article › Academic › peer-review

47 Citations (Scopus)

2014

No evidence for an association of osteopontin plasma levels with disease activity in multiple sclerosis

Runia, T., van Meurs, M., Nasserinejad, K. & Hintzen, R., 2014, In: Multiple Sclerosis. 20, 12, p. 1670-1671 2 p.

Research output: Contribution to journal › Article › Academic

13 Citations (Scopus)

2013

CD44 variant isoforms control experimental autoimmune encephalomyelitis by affecting the lifespan of the pathogenic T cells

Ghazi-Visser, L., Laman, J. D., Nagel, S., Van Meurs, M., Van Riel, D., Tzankov, A., Frank, S., Adams, H., Wolk, K., Terracciano, L., Melief, M. J., Sabat, R. & Günthert, U., Sept 2013, In: FASEB Journal. 27, 9, p. 3683-3701 19 p.

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14 Citations (Scopus)

63 Downloads (Pure)

2012

Decreased systemic IL-7 and soluble IL-7R alpha in multiple sclerosis patients

Kreft, K., Verbraak, E., Wierenga - Wolf, A., van Meurs, M., Oostra, B., Laman, J. & Hintzen, R., 2012, In: Genes and Immunity. 13, 7, p. 587-592 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

39 Citations (Scopus)

Orbit-Infiltrating Mast Cells, Monocytes, and Macrophages Produce PDGF Isoforms that Orchestrate Orbital Fibroblast Activation in Graves' Ophthalmopathy

Steensel, L., Paridaens, D., van Meurs, M., van Hagen, P. M., van den Bosch, W., Kuijpers, R., Drexhage, H., Hooijkaas, H. & Dik, W., 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 3, p. E400-E408

Research output: Contribution to journal › Article › Academic › peer-review

69 Citations (Scopus)

The IL-7R alpha Pathway Is Quantitatively and Functionally Altered in CD8 T Cells in Multiple Sclerosis

Kreft, K., Verbraak, E., Wierenga - Wolf, A., van Meurs, M., Oostra, B., Laman, J. & Hintzen, R., 2012, In: Journal of Immunology. 188, 4, p. 1874-1883 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

26 Citations (Scopus)

2011

Effects of Early IL-17A Neutralization on Disease Induction in a Primate Model of Experimental Autoimmune Encephalomyelitis

Kap, Y., Jagessar, A., van Driel, N., Blezer, E., Bauer, J., van Meurs, M., Smith, P., Laman, J. & Hart, B., 2011, In: Journal of NeuroImmune Pharmacology. 6, 3, p. 341-353 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

24 Citations (Scopus)

Myelin ingestion alters macrophage antigen-presenting function in vitro and in vivo

van Zwam, M., Samsom, J., Nieuwenhuis, E., Melief, M.-J., Wierenga - Wolf, A., Dai, R., Talens, S., van Meurs, M., Voerman, J., Boven, L. & Laman, J., 2011, In: Journal of Leukocyte Biology. 90, p. 123-132 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

14 Citations (Scopus)

2010

Differential expression of the EGF-TM7 family members CD97 and EMR2 in lipid-laden macrophages in atherosclerosis, multiple sclerosis and Gaucher disease

van Eijk, M., Aust, G., Brouwer, M., van Meurs, M., Voerman, J., Dijke, I., Pouwels, W., Sandig, I., Wandel, E., Aerts, J., Boot, R., Laman, J. & Hamann, J., 2010, In: Immunology Letters. 129, 2, p. 64-71 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

19 Citations (Scopus)

Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11 beta-hydroxysteroid dehydrogenases in multiple sclerosis: Implications for lesion pathogenesis

Heidbrink, C., Hausler, S., Buttmann, M., Ossadnik, M., Strik, H., Keller, A., Buck, D., Verbraak, E., van Meurs, M., Krockenberger, M., Mehling, M., Mittelbronn, M., Laman, J., Wiendl, H. & Wischhusen, J., 2010, In: Brain Behavior & Immunity. 24, 6, p. 975-984 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

2009

A Monoclonal Antibody Selection for Immunohistochemical Examination of Lymphoid Tissues From Non-human Primates

Kap, Y., van Meurs, M., van Driel, N., Koopman, G., Melief, M.-J., Brok, H., Laman, J. & Hart, B., 2009, In: Journal of Histochemistry & Cytochemistry. 57, 12, p. 1159-1167 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Scopus)

Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE

van Zwam, M., Huizinga, R., Melief, M.-J., Wierenga - Wolf, A., van Meurs, M., Voerman, J., Biber, K., Boddeke, H., Hopken, U., Meisel, C., Meisel, A., Bechmann, I., Hintzen, R., Hart, B., Amor, S., Laman, J. & Boven, L., 2009, In: Journal of Molecular Medicine. 87, 3, p. 273-286 14 p.

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113 Citations (Scopus)

19 Downloads (Pure)

First trimester interleukin 8 levels are associated with postpartum relapse in multiple sclerosis

Neuteboom, R., Verbraak, E., Voerman, J., van Meurs, M., Steegers, E., de Groot, C., Laman, J. & Hintzen, R., 2009, In: Multiple Sclerosis. 15, 11, p. 1356-1358 3 p.

Research output: Contribution to journal › Article › Academic

20 Citations (Scopus)

Serum leptin levels during pregnancy in multiple sclerosis

Neuteboom, R., Verbraak, E., Voerman, J., van Meurs, M., Steegers, E., de Groot, C., Laman, J. & Hintzen, R., 2009, In: Multiple Sclerosis. 15, 8, p. 907-912 6 p.

Research output: Contribution to journal › Article › Academic

12 Citations (Scopus)

Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis

van Zwam, M., Huizinga, R., Heijmans, N., van Meurs, M., Wierenga - Wolf, A., Melief, M.-J., Hintzen, R., Hart, B., Amor, S., Boven, L. & Laman, J., 2009, In: Journal of Pathology. 217, 4, p. 543-551 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

112 Citations (Scopus)

T-cell responses to neurofilament light protein are part of the normal immune repertoire

Huizinga, R., Hintzen, R., Assink, K., van Meurs, M. & Amor, S., 2009, In: International Immunology. 21, 4, p. 433-441 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

17 Citations (Scopus)

2008

Enforced expression of GATA3 allows differentiation of IL-17-producing cells, but contrains Th17-mediated pathology

Hamburg, J. P., De Jong - de Bruijn, M., Ribeiro de Almeida, C., van Zwam, M., van Meurs, M., Haas, E., Boon, L., Samsom, J. & Hendriks, R., 2008, In: European Journal of Immunology. 38, p. 2573-2586 14 p.

Research output: Contribution to journal › Article › Academic › peer-review

44 Citations (Scopus)

2007

The human CMV-UL86 peptide 981-1003 shares a crossreactive T-cell epitope with the encephalitogenic MOG peptide 34-56, but lacks the capacity to induce EAE in rhesus monkeys

Brok, H., Boven, L., van Meurs, M., de Rosbo, N., Celebi-Paul, L., Kap, Y., Jagessar, A., Hintzen, R., Keir, G., Bajramovic, J., Ben-Nun, A., Bauer, J., Laman, J., Amor, S. & Hart, B., 2007, In: Journal of Neuroimmunology. 182, 1-2, p. 135-152 18 p.

Research output: Contribution to journal › Article › Academic › peer-review

48 Citations (Scopus)

2006

Myelin-laden macrophages are anti-inflammatory, consistent with foam cells in multiple sclerosis

Boven, L., van Meurs, M., van Zwam, M., Wierenga - Wolf, A., Hintzen, R., Boot, R., Aerts, J., Amor, S., Nieuwenhuis, E. & Laman, J., 2006, In: Brain. 129(Pt 2), p. 517-526 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

281 Citations (Scopus)

Phagocytes containing a disease-promoting toll-like receptor/nod ligand are present in the brain during demyelinating disease in primates

Visser, L., Melief, M.-J., van Riel, D., van Meurs, M., Sick, E., Inamura, S., Bajramovic, J., Amor, S., Hintzen, R., Boven, L., Hart, B. & Laman, J., 2006, In: American Journal of Pathology. 169, 5, p. 1671-1685 15 p.

Research output: Contribution to journal › Article › Academic › peer-review

57 Citations (Scopus)

2005

Decay-accelerating factor (CD55) is expressed by neurons in response to chronic but not acute autoimmune central nervous system inflammation associated with complement activation

van Beek, J., van Meurs, M., Hart, B., Brok, H., Neal, J., Chatagner, A., Harris, C., Omidvar, N., Morgan, B., Laman, J. & Gasque, P., 2005, In: Journal of Immunology. 174, 4, p. 2353-2365 13 p.

Research output: Contribution to journal › Article › Academic › peer-review

56 Citations (Scopus)

Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease

Visser, L., van Riel, D., de Heer, H., Boven, L., van Meurs, M., Melief, M.-J., Zahringer, U., van Strijp, J., Lambrecht, B., Nieuwenhuis, E. & Laman, J., 2005, In: Journal of Immunology. 174, 2, p. 808-816 9 p.

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104 Citations (Scopus)

16 Downloads (Pure)

Severe T-cell depletion from the PALS leads to altered spleen composition in common marmosets with experimental autoimmune encephalomyelitis (EAE)

de Vos, A., van Riel, D., van Meurs, M., Brok, H., Boon, L., Hintzen, R., Claassen, E. & Laman, J., 2005, In: Journal of Neuroimmunology. 161, 1-2, p. 29-39 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

2004

Differential expression of cytokines in UV-B-exposed skin of patients with polymorphous light eruption

Kölgen, W., van Meurs, M., Jongsma, M., van Weelden, H., Bruijnzeel-Koomen, C., Knol, E., van Vloten, W., Laman, J. & de Gruijl, F., 2004, In: Archives of Dermatology. 140, p. 295-302 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

53 Citations (Scopus)

Gaucher cells demonstrate a distinct macrophage phenotype and resemble alternatively activated macrophages

Boven, L., van Meurs, M., Boot, R., Mehta, A., Boon, L., Aerts, J. & Laman, J., 2004, In: American Journal of Clinical Pathology. 122, p. 359-369 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

233 Citations (Scopus)

In situ demonstration of CD40- and CD154-positive cells in psoriatic lesions and keratinocyte production of chemokines by CD40 ligation in vitro

Pasch, M., Timar, K., van Meurs, M., Heydendael, V., Bos, J., Laman, J. & Asghar, S., 2004, In: Journal of Pathology. 203, p. 839-848 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Marked elevation of the chemokine CCL18 / PARC in Gaucher disease: a novel surrogate marker for assessing therapeutic intervention

Boot, R., Verhoek, M., de Fost, M., Hollak, C., Maas, M., Bleijlevens, B., van Breemen, M., van Meurs, M., Boven, L., Laman, J., Moran, M., Cox, T. & Aerts, J., 2004, In: Blood. 103, p. 33-39 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

277 Citations (Scopus)

2002

Endogenous interleukin-12 is critical for controlling the late but not the early stage of Leishmania mexicana infection in C57BL/6 mice

Torrentera, F., Laman, J., van Meurs, M., Adorini, L., Muraille, E. & Carlier, Y., 2002, In: Infection & Immunity. 70, 9, p. 5075-5080 6 p.

Research output: Contribution to journal › Article › Academic › peer-review

20 Citations (Scopus)

Expression of the EGF-TM7 receptor CD97 and its ligand CD55 (DAF) in multiple sclerosis

Visser, L., de Vos, A., Hamann, J., Melief, M.-J., van Meurs, M., Lier, R., Laman, J. & Hintzen, R., 2002, In: Journal of Neuroimmunology. 132, p. 156-163 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

47 Citations (Scopus)

Prevention of experimental autoimmune encephalomyelitis in common marmosets using an human anti-IL-12p40 monoclonal antibody.

Brok, H., van Meurs, M., Blezer, E., Schantz, A., Peritt, D., Treacy, G., Laman, J., Bauer, J. & Hart, B., 2002, In: Journal of Immunology. 169, p. 6554-6563 10 p.

Research output: Contribution to journal › Article › Academic › peer-review

Protection of marmoset monkeys against EAE by treatment with a murine antibody blocking CD40 (mu5D12)

Laman, J., Hart, B., Brok, H., van Meurs, M., Schellekens, M., Kasran, A., Boon, L., Bauer, J., Boer, M. & Ceuppens, J., 2002, In: European Journal of Immunology. 32, p. 2218-2228 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

61 Citations (Scopus)

Significance of peptidoglycan, a proinflammatory bacterial antigen in atherosclerotic arteries and its associated with vulnerable plaques

Laman, J., Schoneveld, A., Moll, F., van Meurs, M. & Pasterkamp, G., 2002, In: American Journal of Cardiology. 90, p. 119-123 5 p.

Research output: Contribution to journal › Article › Academic › peer-review

86 Citations (Scopus)

Transfer of central nervous system autoantigens and presentation in secondary lymphoid organs

de Vos, A., van Meurs, M., Brok, H., Boven, L., Hintzen, R., Valk, P., Ravid, R., Rensing, S., Boon, L., Hart, B. & Laman, J., 2002, In: Journal of Immunology. 169, p. 5415-5423 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

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229 Citations (Scopus)

19 Downloads (Pure)

2001

Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis

Arslan, L., van Meurs, M., Melief, M.-J., Ang, C., Buljevac, D., Ravid, R., Hazenberg, M. & Laman, J., 2001, In: Brain. 124, p. 1544-1554 11 p.

Research output: Contribution to journal › Article › Academic › peer-review

Open Access

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116 Citations (Scopus)

11 Downloads (Pure)

Carrier-mediated enhancement of cognate T cell help: the basis for enhanced immunogenicity of meningococcal outer membrane protein polysaccharide conjugate vaccine

Pérez-Melgosa, M., Ochs, H., Linsley, P., Laman, J., van Meurs, M., Flavell, R., Ernst, R., Miller, S. & Wilson, C., 2001, In: European Journal of Immunology. 31, p. 2373-2381 9 p.

Research output: Contribution to journal › Article › Academic › peer-review

36 Citations (Scopus)

Novel monoclonal antibodies against proteolipid protein peptide 139-151 demonstrate demyelination and myelin uptake by macrophages in MS and marmoset EAE lesions

Laman, J., Visser, L., Maassen, C., van Meurs, M., Schellekens, M., Hart, B., de Groot, C. & de Jong, L., 2001, In: Journal of Neuroimmunology. 119, p. 124-130 7 p.

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Prevention of experimental autoimmune encephalomyelitis in the common marmoset (Callithrix jacchus) using a chimeric antagonist monoclonal antibody against human CD40 is associated with altered B cell responses

Boon, L., Brok, H., Bauer, J., Ortiz-Buijsse, A., Schellekens, M., Ramdien-Murli, S., Blezer, E., van Meurs, M., Ceuppens, J., Boer, M., Hart, B. & Laman, J., 2001, In: Journal of Immunology. 167, p. 2942-2949 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

110 Citations (Scopus)

2000

A new primate model for multiple sclerosis in the common marmoset

Hart, B., van Meurs, M., Brok, H., Massacesi, L., Bauer, J., Boon, L., Bontrop, R. & Laman, J., 2000, In: Immunology Today. 21, 6, p. 290-297 8 p.

Research output: Contribution to journal › Article › Academic › peer-review

104 Citations (Scopus)

Marjan van Meurs

Research output

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