Personal profile
Research interests
I am a Medical Doctor and Molecular Epidemiologist currently serving as an Associate Professor at the Department of Epidemiology, Erasmus MC Rotterdam. I lead the "Molecular & Systems Epidemiology" research line as Principal Investigator, heading a dynamic team of MSc students, PhD candidates, postdoctoral researchers, and lab technicians.
My research primarily focuses on uncovering genetic determinants and identifying novel biomarkers for complex diseases, including Alzheimer’s disease, cardiometabolic disorders, and fatty liver disease. To achieve this, we integrate multi-omics data from large-scale epidemiological studies, employing advanced analytical methods and state-of-the-art molecular techniques. This integrative approach aims to unravel the underlying mechanisms of age-related diseases and to discover biomarkers that can facilitate early diagnosis and risk stratification.
Beyond research, I am actively involved in academic teaching, coordinating multiple courses offered by the Netherlands Institute for Health Sciences (NIHES), part of the Erasmus MC Graduate School. I also coordinate the omics data within the population-based Rotterdam Study cohort and manage the family-based Erasmus Rucphen Family (ERF) study.
Furthermore, I actively collaborate in numerous international multicenter projects through various consortia focused on population omics and age-related diseases.
Education/Academic qualification
PhD, The Role of MicroRNAs in Age-Related Disorders : From population-based genetic studies to experimental validation
5 Sept 2011 → 5 Jul 2017
Award Date: 5 Jul 2017
Keywords
- R Medicine (General)
- RZ Other systems of medicine
- RA0421 Public health. Hygiene. Preventive Medicine
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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Collaborations and top research areas from the last five years
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Metabolic profiles of nighttime road traffic noise exposure: A multi-cohort study in the European LongITools project
He, Y., Ginos, B. N. R., Kerckhoffs, J., Voortman, T., Ghanbari, M., Nedelec, R., Cheng, S. L., Ronkainen, J., Kantomaa, M., Kavousi, M., Pulakka, A., Hoek, G. & Sebert, S., 1 Mar 2026, In: Environmental Research. 294, 123887.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Plasma metabolomic signatures of all and cause-specific cancers: a multi-platform population-based study
Shuai, Y., Ruiter, R., Stricker, B. H., Ikram, M. A. & Ghanbari, M., 20 Feb 2026, In: Metabolomics. 22, 2, 27.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile3 Downloads (Pure) -
Immune Signatures of Smoking: Cytokine and Immunoglobulin Dysregulation and Partial Reversibility in a Population-Based Study
Leonard, S. E., Ghanbari, M., Lahousse, L., van Meurs, J. B. J., van Hagen, P. M., Chaker, L. & Dalm, V. A. S. H., 19 Jan 2026, In: Journal of Clinical Immunology. 46, 1, 9.Research output: Contribution to journal › Article › Academic › peer-review
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Brain Atrophy Associated With Risk Variant rs10191329 Extends Beyond Multiple Sclerosis
Corsten, C. E. A., Marques, A. M., Vinke, E. J., de Mol, C. L., Neuteboom, R. F., Ikram, M. K., Ghanbari, M., Wolters, F. J., Wokke, B., Vernooij, M. W. & Smolders, J., 5 Jan 2026, (E-pub ahead of print) In: Annals of Neurology.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile1 Downloads (Pure) -
Genome-wide gene-sleep interaction study identifies novel lipid loci in 732,564 participants
Noordam, R., Wang, W., Nagarajan, P., Wang, H., Brown, M. R., Bentley, A. R., Hui, Q., Kraja, A. T., Morrison, J. L., O'Connel, J. R., Lee, S., Schwander, K., Bartz, T. M., de las Fuentes, L., Feitosa, M. F., Guo, X., Hanfei, X., Harris, S. E., Huang, Z. & Kals, M. & 129 others, , Jan 2026, In: Atherosclerosis. 412, 120603.Research output: Contribution to journal › Article › Academic › peer-review
Open AccessFile5 Downloads (Pure)