prof. dr. P. Martin van Hagen

Search results

• 2020

  Defective formation of IgA memory B cells, Th1 and Th17 cells in symptomatic patients with selective IgA deficiency

  Grosserichter - Wagener, C., Franco-Gallego, A., Ahmadi, F., Moncada-Velez, M., Dalm, V. A. S. H., Rojas, J., Orrego, J., Vargas, N., Hammarstrom, L., Schreurs, M., Dik, W., van Hagen, P. M., Boon, L., Dongen, J., van der Burg, M., Pan-Hammarstrom, Q., Franco, J. & van Zelm, M., 2020, In: Clinical & Translational Immunology. 9, 5, e1130.

  Research output: Contribution to journal › Article › Academic › peer-review

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  16 Citations (Scopus)

  63 Downloads (Pure)

• IgG4-Related Disease of Skull Base: Case Series of 3 Patients with Headache

  Detiger, S., Karim, F., Monserez, D., Verdijk, R., van Hagen, P. M., Paridaens, D. & van Laar, J., 2020, In: World Neurosurgery. 134, p. 536-539 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• Infliximab treatment in pathology-confirmed neurosarcoidosis

  Fritz, D., Timmermans, M., van Laar, J., van Hagen, P. M., Siepman, D., van de Beek, D. & Brouwer, M., 2020, In: Neurology(R) neuroimmunology & neuroinflammation. 7, 5

  Research output: Contribution to journal › Article › Academic › peer-review

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  29 Citations (Scopus)

  92 Downloads (Pure)

• Inverse correlation between serum complement component C1q levels and whole blood type-1 interferon signature in active tuberculosis and QuantiFERON-positive uveitis: implications for diagnosis

  Schrijver, B., Dijkstra, D., Borggreven, N., Nora, R., Huijser, E., Versnel, M., van Hagen, P. M., Joosten, S., Trouw, L. & Dik, W., 2020, In: Clinical & Translational Immunology. 9, 10, e1196.

  Research output: Contribution to journal › Article › Academic › peer-review

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  7 Citations (Scopus)

  21 Downloads (Pure)

• Leukocyte toll-like receptor?expression in pathergy positive and negative Behçet's disease patients

  van der Houwen, T., Dik, W., Goeijenbier, M., Hayat, M., Nagtzaam, N., van Hagen, P. M. & van Laar, J., 2020, In: Rheumatology (Oxford, England). 59, 12, p. 3971-3979 9 p.

  Research output: Contribution to journal › Article › Academic

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  18 Citations (Scopus)

  23 Downloads (Pure)

• Low IgA Associated With Oropharyngeal Microbiota Changes and Lung Disease in Primary Antibody Deficiency

  Berbers, R., Hoesein, F., Ellerbroek, P., van Montfrans, J., Dalm, V. A. S. H., van Hagen, P. M., Paganelli, F. L., Viveen, M., Rogers, M. R. C., Jong, P., Uh, H., Willems, R. & Leavis, H., 2020, In: Frontiers in Immunology. 11, 1245.

  Research output: Contribution to journal › Article › Academic

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  29 Citations (Scopus)

  10 Downloads (Pure)

• Prevalence of Positive QuantiFERON-TB Gold In-Tube Test in Uveitis and its Clinical Implications in a Country Nonendemic for Tuberculosis

  Groen, F., van Laar, J., Bakker, M., van Hagen, P. M., Hardjosantoso, H. & Rothova, A., 2020, In: American Journal of Ophthalmology. 211, p. 151-158 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  13 Citations (Scopus)

  80 Downloads (Pure)

• Rapid Low-Cost Microarray-Based Genotyping for Genetic Screening in Primary Immunodeficiency

  Suratannon, N., Wijck, R., Broer, L., Xue, M., Meurs, J., Barendregt, B., Burg, M., Dik, W., Chatchatee, P., Langerak, T., Swagemakers, S., Goos, J., Mathijssen, I., Dalm, V., Suphapeetiporn, K., Heezen, K., Drabwell, J., Uitterlinden, A., Spek, P. & Hagen, P., 2020, In: Frontiers in Immunology. 11, 614.

  Research output: Contribution to journal › Article › Academic › peer-review

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  19 Citations (Scopus)

  6 Downloads (Pure)

• What Works When Treating Granulomatous Disease in Genetically Undefined CVID? A Systematic Review

  van Stigt, A., Dik, W., Kamphuis, L., Smits, B., van Montfrans, J., van Hagen, P. M., Dalm, V. A. S. H. & Ijspeert, H., 2020, In: Frontiers in Immunology. 11, 606389.

  Research output: Contribution to journal › Article › Academic

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  11 Citations (Scopus)

  87 Downloads (Pure)
• 2019

  Adalimumab provides long-lasting clinical improvement in refractory mucocutaneous Behcet's disease without formation of antidrug antibodies

  Verboom, D., van der Houwen, T., Kappen, J., van Daele, P., Dik, W., Schreurs, M., van Hagen, P. M. & van Laar, J., 2019, In: Clinical & Experimental Rheumatology. 37, 6, p. 43-47 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  6 Citations (Scopus)

• ALPK1 missense pathogenic variant in five families leads to ROSAH syndrome, an ocular multisystem autosomal dominant disorder

  Williams, L., Javed, A., Sabri, A., Morgan, D., Huff, C., Grigg, J., Heng, X., Khng, A., Hollink, I., Morrison, M. A., Owen, L., Anderson, K., Kinard, K., Greenlees, R., Novacic, D., Sen, H., Zein, W., Rodgers, G., Vitale, A. & Haider, N. & 21 others, Hillmer, A., Ng, P., Shankaracharya, Cheng, A., Zheng, L., Gillies, M., van Slegtenhorst, M., van Hagen, P. M., Missotten, T., Farley, G., Polo, M., Malatack, J., Curtin, J., Martin, F., Arbuckle, S., Alexander, S., Chircop, M., Davila, S., Digre, K., Jamieson, R. & DeAngelis, M., 2019, In: Genetics in Medicine. 21, 9, p. 2103-2115 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  32 Citations (Scopus)

  20 Downloads (Pure)

• Basic Fibroblast Growth Factor Induces Adipogenesis in Orbital Fibroblasts: Implications for the Pathogenesis of Graves' Orbitopathy

  Schrijver, B., Kooiman, M., Kasteleijn, E., Neelen, C., Virakul, P., Paridaens, D., Peeters, R., van Hagen, P. M., Dalm, V. A. S. H. & Dik, W., 2019, In: Thyroid. 29, 3, p. 395-404 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  13 Citations (Scopus)

• Efficacy of Baricitinib in the Treatment of Chilblains Associated With Aicardi-Goutieres Syndrome, a Type I Interferonopathy

  Meesilpavikkai, K., Dik, W., Schrijver, B., Van Helden - Meeuwsen, C., Versnel, M., van Hagen, P. M., Bijlsma, E., Ruivenkamp, C., Oele, M. & Dalm, V. A. S. H., 2019, In: ARTHRITIS & RHEUMATOLOGY. 71, 5, p. 829-831 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  44 Citations (Scopus)

  17 Downloads (Pure)

• Endocrine Disorders Are Prominent Clinical Features in Patients With Primary Antibody Deficiencies

  Coopmans, E., Chunharojrith, P., Neggers, S. J. C. M. M., Ent, M., Swagemakers, S., Hollink, I., Barendregt, B., van der Spek, P., van der Lely, A., van Hagen, P. M. & Dalm, V. A. S. H., 2019, In: Frontiers in Immunology. 10, 2079.

  Research output: Contribution to journal › Article › Academic

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  9 Citations (Scopus)

  29 Downloads (Pure)

• IgG4-related diseases: state of the art on clinical practice guidelines

  Iaccarino, G., Talarico, R., Scirè, C., Amoura, Z., Burmester, G., Doria, A., Faiz, K., van Hagen, P. M., Mosca, M. & Alexander, T., 2019, In: RMD Open. 4, Suppl 1, p. e000787 e000787.

  Research output: Contribution to journal › Article › Academic › peer-review
  29 Citations (Scopus)

• Imaging of Bronchial Pathology in Antibody Deficiency: Data from the European Chest CT Group

  Schutz, K., Alecsandru, D., Grimbacher, B., Haddock, J., Bruining, A., Driessen, G., Vries, E., van Hagen, P. M., Hartmann, I., Fraioli, F., Milito, C., Mitrevski, M., Quinti, I., Serra, G., Kelleher, P., Loebinger, M., Litzman, J., Postranecka, V., Thon, V. & Babar, J. & 26 others, Condliffe, A., Exley, A., Kumararatne, D., Screaton, N., Jones, A., Bondioni, M., Lougaris, V., Plebani, A., Soresina, A., Sirignano, C., Spadaro, G., Galal, N., Gonzalez-Granado, L., Dettmer, S., Stirling, R., Chapel, H., Lucas, M., Patel, S., Farber, C., Meyts, I., Banerjee, A., Hackett, S., Hurst, J., Warnatz, K., Gathmann, B. & Baumann, U., 2019, In: Journal of Clinical Immunology. 39, 1, p. 45-54 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  25 Citations (Scopus)

• MxA is a clinically applicable biomarker for type I interferon activation in systemic lupus erythematosus and systemic sclerosis

  Huijser, E., Van Helden - Meeuwsen, C., Groot, N., Bodewes, I., Wahadat, M., Schreurs, M., van Daele, P., Dalm, V. A. S. H., van Laar, J., van Hagen, P. M., Waris, M., Kamphuis, S. & Versnel, M., 2019, In: Rheumatology. 58, 7, p. 1302-1303 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  9 Citations (Scopus)

• Precursor B-cell development in bone marrow of Good syndrome patients

  del Pino Molina, L., Wentink, M., van Deuren, M., van Hagen, P. M., Smith, C. & van der Burg, M., 2019, In: Clinical Immunology. 200, p. 39-42 4 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  13 Citations (Scopus)

• Safety and tolerability of subcutaneous immunoglobulin 20% in primary immunodeficiency diseases from two continents

  Suez, D., Krivan, G., Jolles, S., Stein, M., Gupta, S., Paris, K., van Hagen, P. M., Brodszki, N., Engl, W., Leibl, H., McCoy, B. & Yel, L., 2019, In: Immunotherapy. 11, 12, p. 1057-1065 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  12 Citations (Scopus)

• Sensitivity and specificity of serum soluble interleukin-2 receptor for diagnosing sarcoidosis in a population of patients suspected of sarcoidosis

  Eurelings, L., Miedema, J., Dalm, V. A. S. H., van Daele, P., van Hagen, P. M., van Laar, J. & Dik, W., 2019, In: PLoS One (online). 14, 10, p. e0223897 e0223897.

  Research output: Contribution to journal › Article › Academic › peer-review

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  70 Citations (Scopus)

  30 Downloads (Pure)

• The treatment outcomes in IgG4-related orbital disease: a systematic review of the literature

  Detiger, S., Karim, F., Verdijk, R., van Hagen, P. M., van Laar, J. & Paridaens, D., 2019, In: Acta Ophthalmologica. 97, 5, p. 451-459 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  36 Citations (Scopus)
• 2018

  Hydroxychloroquine affects bone resorption both in vitro and in vivo

  Both, T., Zillikens, M. C., Schreuders-Koedam, M., Vis, M., Lam, W.-K., Weel, A. E. A. M., van Leeuwen, J. P. T. M., van Hagen, P. M., van der Eerden, B. C. J. & van Daele, P. L. A., Feb 2018, In: Journal of Cellular Physiology. 233, 2, p. 1424-1433 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • In Vitro 100%
  • Hydroxychloroquine 100%
  • Osteolysis 100%
  • Osteoclast 45%
  • Bone Density 27%
  23 Citations (Scopus)

• Baricitinib treatment in a patient with a gain-of-function mutation in signal transducer and activator of transcription 1 (STAT1)

  Meesilpavikkai, K., Dik, W., Schrijver, B., Nagtzaam, N., Sluijs, S., van Hagen, P. M. & Dalm, V. A. S. H., 2018, In: Journal of Allergy and Clinical Immunology. 142, 1, p. 328-330 3 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  36 Citations (Scopus)

• Chemotherapy-induced exacerbations of thyroid orbitopathy in a patient with B-cell lymphoma

  Liu, C., Dalm, V. A. S. H., van Hagen, P. M., Boer, F. & Paridaens, D., 2018, In: Orbit. 37, 4, p. 299-302 4 p.

  Research output: Contribution to journal › Article › Academic
  1 Citation (Scopus)

• Dabigatran inhibits intravitreal thrombin activity

  Bastiaans, J., Mulder, V., van Meurs, J., Nijenhuis, M., Neelen, C., van Hagen, P. M. & Dik, W., 2018, In: Acta Ophthalmologica. 96, 5, p. 452-458 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  5 Citations (Scopus)

• Effect of Neoadjuvant Chemoradiotherapy on Health-Related Quality of Life in Esophageal or Junctional Cancer: Results From the Randomized CROSS Trial

  Noordman, B., Verdam, M., Lagarde, S., Hulshof, M., van Hagen, P. M., Henegouwen, M., Wijnhoven, B., van Laarhoven, H., Nieuwenhuijzen, G., Hospers, G., Bonenkamp, J., Cuesta, M., Blaisse, R., Busch, O., Kate, F., Creemers, G., Punt, C., Plukker, J., Verheul, H. & Bilgen, E. & 13 others, van Dekken, H., van der Sangen, M., Rozema, T., Biermann, K., Beukema, J., Piet, A., van Rij, C., Reinders, J., Tilanus, H., Steyerberg, E., van der Gaast, A., Sprangers, M. & van Lanschot, J., 2018, In: Journal of Clinical Oncology. 36, 3, p. 268-+

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  90 Citations (Scopus)

  103 Downloads (Pure)

• Exhaustion of the CD8(+) T Cell Compartment in Patients with Mutations in Phosphoinositide 3-Kinase Delta

  Wentink, M., Müller, Y., Dalm, V. A. S. H., Driessen, G., van Hagen, P. M., van Montfrans, J., van der Burg, M. & Katsikis, P., 2018, In: Frontiers in Immunology. 9, 446.

  Research output: Contribution to journal › Article › Academic

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  34 Citations (Scopus)

  27 Downloads (Pure)

• Expansion of blood IgG(4)(+) B, T(H)2, and regulatory T cells in patients with IgG(4)-related disease

  Heeringa, J., Karim, F., van Laar, J., Verdijk, R., Paridaens, D., van Hagen, P. M. & van Zelm, M., 2018, In: Journal of Allergy and Clinical Immunology. 141, 5, p. 1831-+

  Research output: Contribution to journal › Article › Academic › peer-review
  64 Citations (Scopus)

• Hydroxychloroquine decreases human MSC-derived osteoblast differentiation and mineralization in vitro

  Both, T., van de Peppel, J., Zillikens, M. C., Koedam, M., van Leeuwen, H., van Hagen, P. M., van Daele, P. & van der Eerden, B., 2018, In: Journal of Cellular and Molecular Medicine. 22, 2, p. 873-882 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  12 Citations (Scopus)

  17 Downloads (Pure)

• Hyper-IgE in the allergy clinic-when is it primary immunodeficiency?

  Ponsford, M., Klocperk, A., Pulvirenti, F., Dalm, V. A. S. H., Milota, T., Cinetto, F., Chovancova, Z., Rial, M., Sediva, A., Litzman, J., Agostini, C., van Hagen, P. M., Quinti, I. & Jolles, S., 2018, In: Allergy. 73, 11, p. 2122-2136 15 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  39 Citations (Scopus)

• Identification of CVID Patients With Defects in Immune Repertoire Formation or Specification

  Schouwenburg, P., Ijspeert, H., Knijnenburg, I., Dalm, V. A. S. H., van Hagen, P. M., van Zessen, D., Stubbs, A., Patel, S. & van der Burg, M., 2018, In: Frontiers in Immunology. 9, 2545.

  Research output: Contribution to journal › Article › Academic

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  23 Citations (Scopus)

  13 Downloads (Pure)

• IgG4-gerelateerde ziekte: huidige stand van zaken = IgG4-related disease: current situation

  Karim, F., Hermans, M., Verdijk, R., van Hagen, P. M. & van Laar, J., 2018, In: Nederlands Tijdschrift voor Allergie, Astma en Klinische Immunologie. 18, 1, p. 3-9 7 p.

  Research output: Contribution to journal › Article › Professional › peer-review

• Implications of elevated C-reactive protein and serum amyloid A levels in IgG4-related disease: comment on the article by Perugino et al

  Karim, F., Eurelings, L., van Hagen, P. M. & van Laar, J., 2018, In: ARTHRITIS & RHEUMATOLOGY. 70, 2, p. 317-318 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  4 Citations (Scopus)

• Low frequency of acetyl salicylic acid hypersensitivity in mastocytosis: The results of a double-blind, placebo-controlled challenge study

  Hermans, M., Vet, S., van Hagen, P. M., Gerth van Wijk, R. & van Daele, P., 2018, In: Allergy. 73, 10, p. 2055-2062 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  20 Citations (Scopus)

  25 Downloads (Pure)

• Needs, Perceptions and Education in Sarcoidosis: A Live Interactive Survey of Patients and Partners

  Moor, K., van Manen, M., van Hagen, P. M., Miedema, J., van den Toorn, L., Demirel, Y., Berendse, A., van Laar, J. & Wijsenbeek - Lourens, M., 2018, In: Lung. 196, 5, p. 569-575 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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  26 Citations (Scopus)

  26 Downloads (Pure)

• Retinal Pigment Epithelial Cells Control Early Mycobacterium tuberculosis Infection via Interferon Signaling

  La Distia Nora, R., Walburg, K., van Hagen, P. M., Swagemakers, S., van der Spek, P., Quinten, E., van Velthoven, M., Ottenhoff, T., Dik, W. & Haks, M., 2018, In: Investigative Ophthalmology & Visual Science. 59, 3, p. 1384-1395 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  20 Citations (Scopus)

• Soluble Interleukin-2 Receptor: A Potential Marker for Monitoring Disease Activity in IgG4-Related Disease

  Karim, F., Eurelings, L., Bansie, R., van Hagen, P. M., van Laar, J. & Dik, W., 2018, In: Mediators of Inflammation. 6103064.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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  29 Citations (Scopus)

  24 Downloads (Pure)

• TBK1: A key regulator and potential treatment target for interferon positive Sjogren's syndrome, systemic lupus erythematosus and systemic sclerosis

  Bodewes, I., Huijser, S., Van Helden - Meeuwsen, C., Tas, L., Huizinga, R., Dalm, V. A. S. H., van Hagen, P. M., de Groot, N., Kamphuis, S., van Daele, P. & Versnel, M., 2018, In: Journal of Autoimmunity. 91, p. 97-102 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  48 Citations (Scopus)

• The call for considering follicular helper T cells in IgG(4)-related disease Reply

  Karim, F., Heeringa, J., van Laar, J., Verdijk, R., Dik, W., Paridaens, A., van Hagen, P. M. & van Zelm, M., 2018, In: Journal of Allergy and Clinical Immunology. 141, 5, p. 1958-+

  Research output: Contribution to journal › Article › Academic › peer-review
  1 Citation (Scopus)

• The complement system in glioblastoma multiforme

  Bouwens, T., Kros, J. M., Mustafa, D., van Wijck, R., Ackermans, L., van Hagen, P. M. & van der Spek, P., 2018, In: Acta neuropathologica communications (online). 6, 91.

  Research output: Contribution to journal › Article › Academic › peer-review

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  33 Citations (Scopus)

  8 Downloads (Pure)

• The JAK1/JAK2-inhibitor ruxolitinib inhibits mast cell degranulation and cytokine release

  Hermans, M., Schrijver, B., Neelen, C., Gerth van Wijk, R., van Hagen, P. M., van Daele, P. & Dik, W., 2018, In: Clinical & Experimental Allergy. 48, 11, p. 1412-1420 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

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  46 Citations (Scopus)

  25 Downloads (Pure)

• The treatment outcomes in IgG4-related disease

  Karim, F., Bansie, R., Rombach, S., Paridaens, D., Verdijk, R., van Hagen, P. M. & van Laar, J., 2018, In: Netherlands Journal of Medicine. 76, 6, p. 275-285 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  26 Citations (Scopus)

• Tuberculosis and other causes of uveitis in Indonesia

  La Distia Nora, R., Sitompul, R., Bakker, M., Susiyanti, M., Edwar, L., Sjamsoe, S., Singh, G., van Hagen, P. M. & Rothova, A., 2018, In: Eye-Transactions of the Ophthalmological Societies of the United Kingdom. 32, 3, p. 546-554 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  23 Citations (Scopus)

• Type 1 interferon-inducible gene expression in QuantiFERON Gold TB-positive uveitis: A tool to stratify a high versus low risk of active tuberculosis?

  La Distia Nora, R., Sitompul, R., Bakker, M., Versnel, M., Swagemakers, S., van der Spek, P., Susiyanti, M., Edwar, L., Sjamsoe, S., Singh, G., Handayani, R., Rothova, A., van Hagen, P. M. & Dik, W., 2018, In: PLoS One (online). 13, 10, e0206073.

  Research output: Contribution to journal › Article › Academic › peer-review

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  8 Citations (Scopus)

  17 Downloads (Pure)
• 2017

  A Novel Heterozygous Mutation in the STAT1 SH2 Domain Causes Chronic Mucocutaneous Candidiasis, Atypically Diverse Infections, Autoimmunity, and Impaired Cytokine Regulation

  Meesilpavikkai, K., Dik, W., Schrijver, B., Nagtzaam, N., van Rijswijk, A., Driessen, G., van der Spek, P., van Hagen, P. M. & Dalm, V. A. S. H., 2017, In: Frontiers in Immunology. 8, 274.

  Research output: Contribution to journal › Article › Academic

  Open Access

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  31 Citations (Scopus)

  17 Downloads (Pure)

• Biologic Therapy for HLA-B27-associated Ocular Disorders

  Gueudry, J., Thorne, J., Bansie, R., Braun, J., van Hagen, P. M. & Bodaghi, B., 2017, In: Ocular Immunology and Inflammation. 25, 2, p. 169-178 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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  11 Citations (Scopus)

  49 Downloads (Pure)

• Chronic signs of memory B cell activation in patients with Behcet's disease are partially restored by anti-tumour necrosis factor treatment

  van der Houwen, T., van Hagen, P. M., Timmermans, M., Bartol, B., Lam, K., Kappen, J., van Zelm, M. & van Laar, J., 2017, In: Rheumatology. 56, 1, p. 134-144 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  15 Citations (Scopus)

• Contrasting expression pattern of RNA-sensing receptors TLR7, RIG-I and MDA5 in interferonpositive and interferon-negative patients with primary Sjogren's syndrome

  Maria, N., Steenwijk, E., IJpma, A., Van Helden - Meeuwsen, C., Vogelsang, P., Beumer, W., Brkic, Z., van Daele, P., van Hagen, P. M., van der Spek, P., Drexhage, H. & Versnel, M., 2017, In: Annals of the Rheumatic Diseases. 76, 4

  Research output: Contribution to journal › Article › Academic › peer-review
  66 Citations (Scopus)

• Effective "activated PI3K delta syndrome"-targeted therapy with the PI3Kd inhibitor leniolisib

  Rao, V., Webster, S., Dalm, V. A. S. H., Sediva, A., van Hagen, P. M., Holland, S., Rosenzweig, S., Christ, A., Sloth, B., Cabanski, M., Joshi, A., de Buck, S., Doucet, J., Guerini, D., Kalis, C., Pylvaenaeinen, I., Soldermann, N., Kashyap, A., Uzel, G. & Lenardo, M. & 3 others, Patel, D., Lucas, C. & Burkhart, C., 2017, In: Blood. 130, 21, p. 2307-2316 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  214 Citations (Scopus)

• Genetic defects in PI3K delta affect B-cell differentiation and maturation leading to hypogammaglobulineamia and recurrent infections

  Wentink, M., Dalm, V. A. S. H., Lankester, A., Schouwenburg, P., Scholvinck, L., Kalina, T., Zachova, R., Sediva, A., Lambeck, A., Knijnenburg, I., Dongen, J., Pac, M., Bernatowska, E., van Hagen, P. M., Driessen, G. & van der Burg, M., 2017, In: Clinical Immunology. 176, p. 77-86 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  75 Citations (Scopus)