dr. Sylvia Kamphuis

Search results

• 2025

  Amlexanox inhibits production of type I interferon and suppresses B cell differentiation in vitro: A possible therapeutic option for systemic lupus erythematosus and other systemic inflammatory diseases

  Björk, A., Wahadat, M. J., Sánchez-Blázquez, M., Braams, M., Rip, J., Van Tilburg, S. J., Van Helden-Meeuwsen, C. G., Kamphuis, S., Van Den Bosch, T. P. P., Brkic, Z. & Versnel, M. A., 7 May 2025, In: RMD Open. 11, 2, e005351.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • In Vitro 100%
  • B Cell 100%
  • Cell Differentiation 100%
  • Inflammatory Disorder 100%
  • Interferon Type I 100%
  1 Citation (Scopus)

  3 Downloads (Pure)

• Development of CARRA/PReS-endorsed consensus Core and Expanded Datasets in childhood-onset systemic lupus erythematosus for international registry-based research

  Sadun, R. E., Cooper, J. C., CARRA SLE Committee and PReS Lupus Working Party, Belot, A., Avcin, T., Aggarwal, A., Ainsworth, J., Akinsete, A., Ardoin, S. P., Beresford, M. W., Bortey, L., Brunner, H. I., Chang, J. C., Ciurtin, C., Daftary, A., Eberhard, B., Feldman, C. H., Hedrich, C. M., Hersh, A. O. & Hiraki, L. T. & 26 others, Isenberg, D. A., Kamphuis, S., Knight, A. M., Lambert, L., Levy, D. M., Marks, S. D., Maxwell, N., Migowa, A., Moore, K., Ozen, S., Ramsey-Goldman, R., Ravelli, A., Reeve, B. B., Rubinstein, T. B., Saad-Magalhaes, C., Sawhney, S., Schanberg, L. E., von Scheven, E., Scott, C., Son, M. B., Tony, G., Weitzman, E. R., Wenderfer, S. E., Woodside, A., Lewandowski, L. B. & Smith, E. M., Feb 2025, In: Annals of the rheumatic diseases. 84, 2, p. 158-168 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Arthritis 100%
  • Pediatric Rheumatology 100%
  • Rheumatology 100%
  • Systemic Lupus Erythematosus 100%
  • Childhood Arthritis 100%
  1 Citation (Scopus)
• 2024

  Learning from serum markers reflecting endothelial activation: longitudinal data in childhood-onset systemic lupus erythematosus

  Bergkamp, S. C., Bergkamp, N. D., Wahadat, M. J., Gruppen, M. P., Rashid, A.N.-S., Tas, S. W., Smit, M. J., Versnel, M. A., van den Berg, J. M., Kamphuis, S. & Schonenberg-Meinema, D., 5 Sept 2024, In: Lupus Science and Medicine. 11, 2, e001190.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Angiopoietin-2 100%
  • Lipid 100%
  • Thrombomodulin 100%
  • CXCL10 100%
  • CCL2 100%
  1 Citation (Scopus)

  15 Downloads (Pure)

• Defining remission in childhood-onset lupus: PReS-endorsed consensus definitions by an international task force

  Smith, E. M. D., Aggarwal, A., Ainsworth, J., the International cSLE T2T Task Force, Al-Abadi, E., Avcin, T., Bortey, L., Burnham, J., Ciurtin, C., Hedrich, C. M., Kamphuis, S., Lambert, L., Levy, D. M., Lewandowski, L., Maxwell, N., Morand, E., Özen, S., Pain, C. E., Ravelli, A. & Saad Magalhaes, C. & 9 others, Pilkington, C., Schonenberg-Meinema, D., Scott, C., Tullus, K., Beresford, M. W., Goilav, B., Goss, N., Oni, L. & Marks, S. D., Jun 2024, In: Clinical Immunology. 263, 110214.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Systemic Lupus Erythematosus 100%
  • Lupus Erythematosus 100%
  • Side Effect 12%
  • Observational Study 12%
  • Immunosuppressive Treatment 12%
  3 Citations (Scopus)

  27 Downloads (Pure)

• Monitoring of Adverse Events and Safety in Autoinflammatory Diseases: Real-Life Data from the Eurofever Registry

  Vyzhga, Y., Frenkel, J., Insalaco, A., Eurofever the Paediatric Rheumatology International Trials Organisation (PRINTO), Anton, J., Koné-Paut, I., Legger, G. E., Fabio, G., Cattalini, M., Kamphuis, S., Hachulla, E., Krause, K., Ekinci, Z., Sanchez-Manubens, J., Van den Berg, J. M., Mora, C. H., Brinkman, D., Labrador, E., Potjewijd, J. & Carlini, L. & 4 others, Bustaffa, M., Caorsi, R., Ruperto, N. & Gattorno, M., Jun 2024, In: Journal of Clinical Immunology. 44, 5, 119.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Adverse Event 100%
  • Autoinflammatory Disease 100%
  • Autoinflammatory Syndromes 100%
  • Neurologic Disease 50%
  • Systemic Disease 50%
  1 Citation (Scopus)

• Management of Autoimmune Encephalitis in a 7-Year-Old Child With CTLA-4 Haploinsufficiency and AMPA Receptor Antibodies: A Case Report

  Quaak, M. S. W., Buijze, M. S. J. S., Verhoeven, V. J. M., Vermont, C., Buddingh, E. P., Heredia, M., Samsom, J. N., Titulaer, M. J., van Rossum, A. M., Kamphuis, S. & Neuteboom, R. F., 10 May 2024, In: Neurology(R) neuroimmunology & neuroinflammation. 11, 4, e200254.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Haploinsufficiency 100%
  • Receptor Antibody 100%
  • Allergic Encephalitis 100%
  • CTLA-4 100%
  • AMPA Receptor 100%
  16 Downloads (Pure)

• Cardiovascular risk in young people with childhood onset systemic lupus erythematosus

  Ciurtin, C., Robinson, G., Butt, M., PReS Lupus Working Party and CARRA Lupus Group, Peng, J., Ardoin, S., Schanberg, L., Boteanu, A., Bouchalova, K., Demir, S., Moraitis, E., Migowa, A., Glackin, Y., Ainsworth, J., Smith, E., Jury, E., Sahin, S., Kamphuis, S. & Lewandowski, L., May 2024, In: The Lancet Rheumatology. 6, 5, p. e258-e263

  Research output: Contribution to journal › Comment/Letter to the editor › Academic › peer-review

  Open Access

  File
  11 Downloads (Pure)

• Neurological phenotype of adenosine deaminase 2 deficient patients: a cohort study

  Verschoof, M. A., van Meenen, L. C. C., Andriessen, M. V. E., Brinkman, D. M. C., Kamphuis, S., Kuijpers, T. W., Leavis, H. L., Legger, G. E., Mulders-Manders, C. M., de Pagter, A. P. J., Rutgers, A., van Well, G. T. J., Coutinho, J. M., Hak, A. E., van Montfrans, J. M. & Klouwer, F. C. C., Jan 2024, In: European Journal of Neurology. 31, 1, e16043.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Cohort Analysis 100%
  • Brain Ischemia 100%
  • Transient Ischemic Attack 66%
  • Neurologic Finding 66%
  • Tumor Necrosis Factor 50%
  4 Citations (Scopus)

  42 Downloads (Pure)
• 2023

  Clinical Symptoms, Laboratory Parameters and Long-Term Follow-up in a National DADA2 Cohort

  Andriessen, M. V. E., Legger, G. E., Bredius, R. G. M., van Gijn, M. E., Hak, A. E., Muller, P. C. E. H., Kamphuis, S., Klouwer, F. C. C., Kuijpers, T. W., Leavis, H. L., Nierkens, S., Rutgers, A., van der Veken, L. T., van Well, G. T. J., Mulders-Manders, C. M. & van Montfrans, J. M., Oct 2023, In: Journal of Clinical Immunology. 43, 7, p. 1581-1596 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Adenosine Deaminase 100%
  • Hemophagocytic Lymphohistiocytosis 80%
  • Immunodeficiency 20%
  • Autoinflammatory Syndromes 20%
  • TNF Inhibitor 20%
  10 Citations (Scopus)

  24 Downloads (Pure)

• Serum Ifnα2 Levels Are Associated with Disease Activity and Outperform Ifn-I Gene Signature in a Longitudinal Childhood-Onset Sle Cohort

  Wahadat, M., Qi, H., van Helden-Meeuwsen, C. G., Huijser, E., van den Berg, L., Hummelman, A., Göpfert, J., Heine, A., Verkaaik, M., Schreurs, M., Dik, W. A., Kamphuis, S. & Versnel, M., 1 Aug 2023, In: Rheumatology. 62, 8, p. 2872-2879 8 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Lupus Erythematosus 100%
  • Gene Signature 100%
  • Interferon Type I 50%
  • Systemic Lupus Erythematosus 50%
  • Reverse Transcription Polymerase Chain Reaction 50%
  9 Citations (Scopus)

  52 Downloads (Pure)

• Dysregulated endothelial cell markers in systemic lupus erythematosus: a systematic review and meta-analysis

  Bergkamp, S. C., Wahadat, M. J., Salah, A., Kuijpers, T. W., Smith, V., Tas, S. W., van den Berg, J. M., Kamphuis, S. & Schonenberg-Meinema, D., 16 May 2023, In: Journal of Inflammation (United Kingdom). 20, 1, 18.

  Research output: Contribution to journal › Review article › Academic › peer-review

  Open Access

  File

  • Meta-Analysis 100%
  • Endothelial Cell 100%
  • Cell Marker 100%
  • Systematic Review 100%
  • Systemic Lupus Erythematosus 100%
  9 Citations (Scopus)

  17 Downloads (Pure)

• PReS-endorsed international childhood lupus T2T task force definition of childhood lupus low disease activity state (cLLDAS)

  Smith, E. M. D., Aggarwal, A., the International cSLE T2T Task Force, Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., Burnham, J., Ciurtin, C., Hedrich, C. M., Kamphuis, S., Lambert, L., Levy, D. M., Lewandowski, L., Maxwell, N., Morand, E., Ozen, S., Pain, C. E., Ravelli, A. & Saad Magalhaes, C. & 8 others, Pilkington, C., Schonenberg-Meinema, D., Scott, C., Tullus, K., Beresford, M. W., Goilav, B., Marks, S. & Oni, L., May 2023, In: Clinical Immunology. 250, 109296.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Disease Activity 100%
  • Lupus Erythematosus 100%
  • Systemic Lupus Erythematosus 42%
  • Rheumatologist 22%
  • Immunosuppressive Drug 14%
  15 Citations (Scopus)

• Targeted multiomics in childhood-onset SLE reveal distinct biological phenotypes associated with disease activity: Results from an explorative study

  Wahadat, M. J., Van Tilburg, S. J., Mueller, Y. M., De Wit, H., Van Helden-Meeuwsen, C. G., Langerak, A. W., Gruijters, M. J., Mubarak, A., Verkaaik, M., Katsikis, P. D., Versnel, M. A. & Kamphuis, S., 3 Apr 2023, In: Lupus Science and Medicine. 10, 1, e000799.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Systemic Lupus Erythematosus 100%
  • Lupus Erythematosus 60%
  • Immunocompetent Cell 40%
  • Cytokine 40%
  • Organ Systems 40%
  4 Citations (Scopus)

  14 Downloads (Pure)

• Towards development of treat to target (T2T) in childhood-onset systemic lupus erythematosus: PReS-endorsed overarching principles and points-to-consider from an international task force

  Smith, E. M. D., Aggarwal, A., Ainsworth, J., Al-Abadi, E., Avcin, T., Bortey, L., Burnham, J., Ciurtin, C., Hedrich, C. M., Kamphuis, S., Levy, D. M., Lewandowski, L. B., Maxwell, N., Morand, E. F., Ozen, S., Pain, C. E., Ravelli, A., Saad Magalhaes, C., Pilkington, C. A. & Schonenberg-Meinema, D. & 3 others, Scott, C., Tullus, K. & Beresford, M. W., 2023, In: Annals of the Rheumatic Diseases. 82, 6, p. 788-798 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Systemic Lupus Erythematosus 100%
  • Pediatric Rheumatology 40%
  • Remission 40%
  • Side Effect 20%
  • Mental Health 20%
  30 Citations (Scopus)

  28 Downloads (Pure)
• 2022

  Gene signature fingerprints stratify SLE patients in groups with similar biological disease profiles: a multicentre longitudinal study

  Wahadat, M. J., Schonenberg-Meinema, D., van Helden-Meeuwsen, C. G., van Tilburg, S. J., Groot, N., Schatorjé, E. J. H., Hoppenreijs, E. P. A. H., Hissink Muller, P. C. E., Brinkman, D. M. C., Dvorak, D., Verkaaik, M., van den Berg, J. M., Bouchalova, K., Kamphuis, S. & Versnel, M. A., 1 Nov 2022, In: Rheumatology (Oxford, England). 61, 11, p. 4344-4354 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Disease Activity 100%
  • Finger Dermatoglyphics 100%
  • Systemic Lupus Erythematosus 100%
  • Diseases 100%
  • Longitudinal Study 100%
  12 Citations (Scopus)

  37 Downloads (Pure)

• Trained Immunity in Primary Sjögren’s Syndrome: Linking Type I Interferons to a Pro-Atherogenic Phenotype

  Huijser, E., van Helden-Meeuwsen, C. G., Grashof, D. G. B., Tarn, J. R., Brkic, Z., Huisman, J. M. A., Wahadat, M. J., van de Werken, H. J. G., Lopes, A. P., van Roon, J. A. G., van Daele, P. L. A., Kamphuis, S., Ng, W. F., Bekkering, S., Joosten, L. A. B., Dik, W. A. & Versnel, M. A., 4 Jul 2022, In: Frontiers in Immunology. 13, 840751.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Interferon Type I 100%
  • Interferon 100%
  • Peripheral Blood Mononuclear Cell 62%
  • Polyinosinic Polycytidylic Acid 50%
  • Tumor Necrosis Factor 25%
  10 Citations (Scopus)

  47 Downloads (Pure)

• Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response

  Lerkvaleekul, B., Veldkamp, S. R., Van Der Wal, M. M., Schatorj, E. J. H., Kamphuis, S. S. M., Van Den Berg, J. M., Hissink Muller, P. C. E., Armbrust, W., Vastert, S. J., Wienke, J., Jansen, M. H. A., Van Royen-Kerkhof, A. & Van Wijk, F., 1 May 2022, In: Rheumatology (United Kingdom). 61, 5, p. 2144-2155 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Interferon Type I 100%
  • Sialoadhesin 100%
  • Dermatomyositis 100%
  • Interferon 100%
  • CXCL10 25%
  30 Citations (Scopus)

  32 Downloads (Pure)

• Anakinra in Patients With Systemic Juvenile Idiopathic Arthritis: Long-term Safety From the Pharmachild Registry

  Giancane, G., Papa, R., the Paediatric Rheumatology International Trials Organisation (PRINTO), Vastert, S., Bagnasco, F., Swart, J. F., Quartier, P., Antón, J., Kamphuis, S., Sanner, H., Glerup, M., De Benedetti, F., Tsitsami, E., Remesal, A., Moreno, E., De Inocencio, J., Myrup, C., Pallotti, C., Koné-Paut, I. & Franck-Larsson, K. & 5 others, Malmström, H., Cederholm, S., Pistorio, A., Wulffraat, N. & Ruperto, N., 1 Apr 2022, In: Journal of Rheumatology. 49, 4, p. 398-407 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Systemic Juvenile Idiopathic Arthritis 100%
  • Anakinra 100%
  • Adverse Event 37%
  • Macrophage Activation Syndrome 25%
  • Infection 25%
  23 Citations (Scopus)

  21 Downloads (Pure)

• Nailfold capillary scleroderma pattern may be associated with disease damage in childhood-onset systemic lupus erythematosus: Important lessons from longitudinal follow-up

  Schonenberg-Meinema, D., Bergkamp, S. C., Nassar-Sheikh Rashid, A., Gruppen, M. P., Middelkamp-Hup, M. A., Armbrust, W., Dolman, K., Hak, A. E., Hissink Muller, P. C. E., Van Onna, M., Swart, J. F., Kuijpers, T. W., Kamphuis, S. S. M., Smith, V. & Van Den Berg, J. M., 9 Feb 2022, In: Lupus Science and Medicine. 9, 1, e000572.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Capillary 100%
  • Systemic Lupus Erythematosus 100%
  • Scleroderma 100%
  • Diseases 100%
  • Disease Activity 40%
  8 Citations (Scopus)

  71 Downloads (Pure)
• 2021

  LLDAS is an attainable treat-to-target goal in childhood-onset SLE

  Wahadat, M. J., Van Den Berg, L., Timmermans, D., Van Rijswijk, K., Van Dijk-Hummelman, A., Bakx, S., Verkaaik, M., Versnel, M. A. & Kamphuis, S., 30 Dec 2021, In: Lupus Science and Medicine. 8, 1, e000571.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Disease Activity 100%
  • Systemic Lupus Erythematosus 100%
  • Lupus Erythematosus 100%
  • Remission 71%
  • SLEDAI 33%
  24 Citations (Scopus)

  38 Downloads (Pure)

• Effects of childhood-onset systemic lupus erythematosus on academic achievements and employment in adult life

  Groot, N., Kardolus, A., Bijl, M., Dolhain, R. J. E. M., Teng, Y. K. O., Zirkzee, E., De Leeuw, K., Fritsch-Stork, R., Burdorf, A., Bultink, I. E. & Kamphuis, S., 1 Jun 2021, In: Journal of Rheumatology. 48, 6, p. 915-923 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  • Systemic Lupus Erythematosus 100%
  • Diseases 57%
  • Occupational Choice 28%
  • Quality of Life 28%
  • Short Form 36 28%
  13 Citations (Scopus)

• Relationship between genetic risk and age of diagnosis in systemic lupus erythematosus

  Canadian Network for Improved Outcomes in SLE (CaNIOS) and APPLE Investigators, 1 Jun 2021, In: Journal of Rheumatology. 48, 6, p. 852-858 7 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  • Systemic Lupus Erythematosus 100%
  • Genetic Risk 100%
  • Single-Nucleotide Polymorphism 10%
  • Quality Control 10%
  • Allele 10%
  24 Citations (Scopus)

• Severe acute respiratory syndrome coronavirus 2 placental infection and inflammation leading to fetal distress and neonatal multi-organ failure in an asymptomatic woman

  Schoenmakers, S., Snijder, P., Verdijk, R. M., Kuiken, T., Kamphuis, S. S. M., Koopman, L. P., Krasemann, T. B., Rousian, M., Broekhuizen, M., Steegers, E. A. P., Koopmans, M. P. G., Fraaij, P. L. A. & Reiss, I. K. M., May 2021, In: Journal of the Pediatric Infectious Diseases Society. 10, 5, p. 556-561 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File

  • Severe Acute Respiratory Syndrome Coronavirus 2 100%
  • Infection 100%
  • Multiple Organ Dysfunction Syndrome 100%
  • Fetus Distress 100%
  • Fibrin Deposition 18%
  66 Citations (Scopus)

  29 Downloads (Pure)
• 2020

  Endothelial and Inflammation Biomarker Profiles at Diagnosis Reflecting Clinical Heterogeneity and Serving as a Prognostic Tool For Treatment Response in Two Independent Cohorts of Patients With Juvenile Dermatomyositis

  Wienke, J., Pachman, L., Morgan, G., Yeo, J., Amoruso, M., Hans, V., Kamphuis, S., Hoppenreijs, E., Armbrust, W., Berg, J., Muller, P., Gelderman, K., Arkachaisri, T., van Wijk, F. & van Royen-kerkhof, A., 2020, In: ARTHRITIS & RHEUMATOLOGY. 72, 7, p. 1214-1226 13 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  30 Citations (Scopus)

  89 Downloads (Pure)

• Opportunistic infections in immunosuppressed patients with juvenile idiopathic arthritis: analysis by the Pharmachild Safety Adjudication Committee

  Giancane, G., Swart, J., Castagnola, E., Groll, A., Horneff, G., Huppertz, H., Lovell, D., Wolfs, T., Herlin, T., Dolezalova, P., Sanner, H., Susic, G., Sztajnbok, F., Maritsi, D., Constantin, T., Vargova, V., Sawhney, S., Rygg, M., Oliveira, S. & Cattalini, M. & 8 others, Bovis, F., Bagnasco, F., Pistorio, A., Martini, A., Wulffraat, N., Ruperto, N., Kamphuis, S. & Paediat Rheumat Trials, O., 2020, In: Arthritis Research and Therapy. 22, 1, 71.

  Research output: Contribution to journal › Article › Academic › peer-review
  30 Citations (Scopus)
• 2019

  American College of Rheumatology Provisional Criteria for Clinically Relevant Improvement in Children and Adolescents With Childhood-Onset Systemic Lupus Erythematosus

  Brunner, H., Holland, M., Beresford, M., Ardoin, S., Appenzeller, S., Silva, C., Jurado, R., Kamphuis, S. & Maldonado, I., 2019, In: Arthritis Care & Research. 71, 5, p. 579-590 12 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  16 Citations (Scopus)

• Effects of immunomodulation in classic infantile Pompe patients with high antibody titers

  Poelman, E., Hoogeveen - Westerveld, M., van den Hout, H., Bredius, R., Lankester, A., Driessen, G., Kamphuis, S., Pijnappel, P. & van der Ploeg, A., 2019, In: Orphanet Journal of Rare Diseases. 14, 71.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  22 Citations (Scopus)

  55 Downloads (Pure)

• European consensus-based recommendations for diagnosis and treatment of immunoglobulin A vasculitis-the SHARE initiative

  Ozen, S., Marks, S., Brogan, P., Groot, N., de Graeff, N., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., McCann, L., Pilkington, C., Ravelli, A., van Royen, A., Uziel, Y., Vastert, B., Wulffraat, N., Kamphuis, S. & Beresford, M., 2019, In: Rheumatology. 58, 9, p. 1607-1616 10 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  220 Citations (Scopus)

• European consensus-based recommendations for the diagnosis and treatment of Kawasaki disease - the SHARE initiative

  de Graeff, N., Groot, N., Ozen, S., Eleftheriou, D., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., McCann, L., Pilkington, C., Ravelli, A., van Royen-kerkhof, A., Uziel, Y., Vastert, B., Wulffraat, N., Kamphuis, S., Brogan, P. & Beresford, M., 2019, In: Rheumatology. 58, 4, p. 672-682 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  127 Citations (Scopus)

• European consensus-based recommendations for the diagnosis and treatment of rare paediatric vasculitides - the SHARE initiative

  de Graeff, N., Groot, N., Brogan, P., Ozen, S., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., Marks, S., McCann, L., Pilkington, C., Ravelli, A., van Royen, A., Uziel, Y., Vastert, B., Wulffraat, N., Kamphuis, S. & Beresford, M., 2019, In: Rheumatology. 58, 4, p. 656-671 16 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  82 Citations (Scopus)

• Galectin-9 and CXCL10 as Biomarkers for Disease Activity in Juvenile Dermatomyositis: A Longitudinal Cohort Study and Multicohort Validation

  Wienke, J., Enders, F., Lim, J., Mertens, J., van den Hoogen, L. L., Wijngaarde, C., Yeo, J., Meyer, A., Otten, H., Fritsch-Stork, R. D. E., Kamphuis, S., Hoppenreijs, E., Armbrust, W., Berg, J., Muller, P., Tekstra, J., Hoogendijk, J., Deakin, C., de Jager, W. & van Roon, J. & 11 others, van der Pol, W., Nistala, K., Pilkington, C., Visser, M., Arkachaisri, T., Radstake, T., van der Kooi, A., Nierkens, S., Wedderburn, L., van Royen-kerkhof, A. & van Wijk, F., 2019, In: ARTHRITIS & RHEUMATOLOGY. 71, 8, p. 1377-1390 14 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

  File
  67 Citations (Scopus)

  16 Downloads (Pure)

• Long-Term Clinical Outcomes in a Cohort of Adults With Childhood-Onset Systemic Lupus Erythematosus

  Groot, N., Shaikhani, D., Teng, Y., de Leeuw, K., Bijl, M., Dolhain, R., Zirkzee, E., Fritsch-Stork, R., Bultink, I. & Kamphuis, S., 2019, In: ARTHRITIS & RHEUMATOLOGY. 71, 2, p. 290-301 12 p.

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  91 Citations (Scopus)

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• MxA is a clinically applicable biomarker for type I interferon activation in systemic lupus erythematosus and systemic sclerosis

  Huijser, E., Van Helden - Meeuwsen, C., Groot, N., Bodewes, I., Wahadat, M., Schreurs, M., van Daele, P., Dalm, V. A. S. H., van Laar, J., van Hagen, P. M., Waris, M., Kamphuis, S. & Versnel, M., 2019, In: Rheumatology. 58, 7, p. 1302-1303 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  11 Citations (Scopus)

• Phenotypic variability and disparities in treatment and outcomes of childhood arthritis throughout the world: an observational cohort study

  Consolaro, A., Giancane, G., Alongi, A., van Dijkhuizen, E., Aggarwal, A., Al-Mayouf, S., Bovis, F., De Inocencio, J., Demirkaya, E., Flato, B., Foell, D., Garay, S., Lazar, C., Lovell, D., Montobbio, C., Miettunen, P., Mihaylova, D., Nielsen, S., Orban, I. & Rumba-Rozenfelde, I. & 120 others, Magalhaes, C., Shafaie, N., Susic, G., Trachana, M., Wulffraat, N., Pistorio, A., Martini, A., Ruperto, N., Ravelli, P., Abdwani, R., Aghighi, Y., Aiche, M., Ailioaie, C., Ayaz, N., Al-Abrawi, S., Alexeeva, E., Anton, J., Apostol, A., Arguedas, O., Avcin, T., Barone, P., Berntson, L., Boteanu, A., Boyko, Y., Burgos-Vargas, R., Penades, I., Chedeville, G., Cimaz, R., Civino, A., Consolini, R., Constantin, T., Cuttica, R., Dallos, T., Martin, N., Manzoni, S., De Cunto, C., Dolezalova, P., Ekelund, M., El Miedany, Y., Espada, G., Christensen, A., Foeldvari, I., Gallizzi, R., Ganser, G., Gerloni, V., Haas, J., Harel, L., Harjacek, M., Hashad, S., Herlin, T., Herrera, C., Hofer, M., Holzinger, D., Horneff, G., Huppertz, H., Iagaru, N., Estrella, A., Ioseliani, M., Joos, R., Oliveira, S., Kamphuis, S., Kasapcopur, O., Katsicas, M., Khubchandani, R., Kondi, A., Kroger, L., La Torre, F., Laday, M., Lahdenne, P., Maggio, M., Magnolia, M., Malagon, C., Malin, M., Martino, S., Melo-Gomes, J., Mesa-del-Castillo, P., Militaru, A., Minden, K., Miniaci, A., Moradinejad, M., Ayala, Z., Nikishina, I., Norambuena, X., Nordal, E., Pagava, K., Panaviene, V., Pastore, S., Pieropan, S., Podda, R., Pruunsild, C., Putto-Laurila, A., Quartier, P., Remesal, A., Rigante, D., Ringold, S., Rutkowska-Sak, L., Rygg, M., Saurenmann, R., Sawhney, S., Scott, C., Shiari, R., Smolewska, E., Sozeri, B., Swart, J., Sztajnbok, F., Torcoletti, M., Tsitsami, E., Tzaribachev, N., Unsal, E., Uziel, Y., Vahasalo, P., Varbanova, B., Vargova, V., Vesely, R., Vijatov-Djuric, G., Vilaiyuk, S., Vojinovic, J., Vougiouka, O., Weiss, P. & Woute, C., 2019, In: Lancet Child & Adolescent Health. 3, 4, p. 255-263 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  148 Citations (Scopus)

• Sacrale osteomyelitis bij een peuter met persisterende onbegrepen hoge koorts

  Hagen, V., Kamphuis, S. & Vermont, C., 2019, In: Praktische Pediatrie. juli 2019

  Research output: Contribution to journal › Article › Professional
• 2018

  Dutch juvenile idiopathic arthritis patients, carers and clinicians create a research agenda together following the James Lind Alliance method: A study protocol

  Schoemaker, C. G., Armbrust, W., Swart, J. F., Vastert, S. J., Van Loosdregt, J., Verwoerd, A., Whiting, C., Cowan, K., Olsder, W., Versluis, E., Van Vliet, R., Fernhout, M. J., Bookelman, S. L., Cappon, J., Van Den Berg, J. M., Schatorjé, E., Muller, P. C. E. H., Kamphuis, S., De Boer, J. & Lelieveld, O. T. H. M. & 5 others, Van Der Net, J., Jongsma, K. R., Van Rensen, A., Dedding, C. & Wulffraat, N. M., 15 Sept 2018, In: Pediatric Rheumatology. 16, 1, 57.

  Research output: Contribution to journal › Article › Academic › peer-review

  Open Access

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  • Caregiver 100%
  • Dutch 100%
  • Arthritis 100%
  • Juvenile Idiopathic Arthritis 100%
  • Clinician 100%
  22 Citations (Scopus)

  14 Downloads (Pure)

• Identification of an Amino Acid Motif in HLA-DR1 That Distinguishes Uveitis in Patients With Juvenile Idiopathic Arthritis

  Haasnoot, A., Schilham, M., Kamphuis, S., Muller, P., Heiligenhaus, A., Foell, D., Minden, K., Ophoff, R., Radstake, T., Hollander, A., Reinards, T., Hiddingh, S., Schalij-Delfos, N., Hoppenreijs, E., van Rossum, M., Wouters, C., Saurenmann, R., Berg, J., Wulffraat, N. & ten Cate, R. & 3 others, de Boer, J., Pulit, S. & Kuiper, J., 2018, In: ARTHRITIS & RHEUMATOLOGY. 70, 7, p. 1155-1165 11 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  40 Citations (Scopus)

• Pharmacovigilance in juvenile idiopathic arthritis patients treated with biologic or synthetic drugs: combined data of more than 15,000 patients from Pharmachild and national registries

  Swart, J., Giancane, G., Horneff, G., Magnusson, B., Hofer, M., Alexeeva, E., Panaviene, V., Bader-Meunier, B., Anton, J., Nielsen, S., Benedetti, F., Kamphuis, S., Stanevica, V., Tracahana, M., Ailioaie, L., Tsitsami, E., Klein, J., Minden, K., Foeldvari, I. & Haas, J. & 9 others, Klotsche, J., Horne, A., Consolaro, A., Bovis, F., Bagnasco, F., Pistorio, A., Martini, A., Wulffraat, N. & Ruperto, N., 2018, In: Arthritis Research & Therapy. 20, 285.

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  73 Citations (Scopus)

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• Successful implementation of a clinical transition pathway for adolescents with juvenile-onset rheumatic and musculoskeletal diseases

  Walter, M., Kamphuis, S., Pelt, P., Vroed, A. & Hazes, M., 2018, In: Pediatric Rheumatology. 16, 50.

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  39 Citations (Scopus)

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• TBK1: A key regulator and potential treatment target for interferon positive Sjogren's syndrome, systemic lupus erythematosus and systemic sclerosis

  Bodewes, I., Huijser, S., Van Helden - Meeuwsen, C., Tas, L., Huizinga, R., Dalm, V. A. S. H., van Hagen, P. M., de Groot, N., Kamphuis, S., van Daele, P. & Versnel, M., 2018, In: Journal of Autoimmunity. 91, p. 97-102 6 p.

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  55 Citations (Scopus)

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• The Dutch version of the Juvenile Arthritis Multidimensional Assessment Report (JAMAR)

  Wulffraat, N., Kamphuis, S., Swart, J., Vastert, S., Van Dijkhuizen, P., van Pelt, P., Hummelman, A., Consolaro, A., Bovis, F. & Ruperto, N., 2018, In: Rheumatology International. 38, p. 139-146 8 p.

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  2 Citations (Scopus)

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• Type I IFN signature in childhood-onset systemic lupus erythematosus: a conspiracy of DNA- and RNA-sensing receptors?

  Wahadat, M., Bodewes, I., Maria, N., Van Helden - Meeuwsen, C., Hummelman, A., Steenwijk, E., Kamphuis, S. & Versnel, M., 2018, In: Arthritis Research & Therapy. 20, 4.

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  48 Citations (Scopus)

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• 2017

  Development of a clinical transition pathway for adolescents in the Netherlands

  Walter, M., Hazes, M., Dolhain, R., Pelt, P., van Dijk, A. & Kamphuis, S., 2017, In: Nursing children and young people. 29, 9, p. 37-43 7 p.

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  9 Citations (Scopus)

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• EULAR/PReS standards and recommendations for the transitional care of young people with juvenile-onset rheumatic diseases

  Foster, H., Minden, K., Clemente, D., Leon, L., McDonagh, J., Kamphuis, S., Berggren, K., Pelt, P., Wouters, C., Waite-Jones, J., Tattersall, R., Wyllie, R., Stones, S., Martini, A., Constantin, T., Schalm, S., Fidanci, B., Erer, B., Dermikaya, E. & Ozen, S. & 1 others, Carmona, L., 2017, In: Annals of the Rheumatic Diseases. 76, 4

  Research output: Contribution to journal › Article › Academic › peer-review
  173 Citations (Scopus)

• European evidence-based recommendations for diagnosis and treatment of childhood-onset systemic lupus erythematosus: the SHARE initiative

  Groot, N., de Graeff, N., Avcin, T., Bader-Meunier, B., Brogan, P., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., Marks, S., McCann, L., Ozen, S., Pilkington, C., Ravelli, A., van Royen-kerkhof, A., Uziel, Y., Vastert, B., Wulffraat, N., Kamphuis, S. & Beresford, M., 2017, In: Annals of the Rheumatic Diseases. 76, 11, p. 1788-1796 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  165 Citations (Scopus)

• European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative

  Groot, N., de Graeff, N., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kenet, G., Kone-Paut, I., Lahdenne, P., Marks, S., McCann, L., Pilkington, C., Ravelli, A., van Royen-kerkhof, A., Uziel, Y., Vastert, S., Wulffraat, N., Ozen, S., Brogan, P. & Kamphuis, S. & 1 others, Beresford, M., 2017, In: Annals of the Rheumatic Diseases. 76, 10, p. 1637-1641 5 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  80 Citations (Scopus)

• European evidence-based recommendations for the diagnosis and treatment of childhood-onset lupus nephritis: the SHARE initiative

  Groot, N., de Graeff, N., Marks, S., Brogan, P., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., McCann, L., Ozen, S., Pilkington, C., Ravelli, A., van Royen-kerkhof, A., Uziel, Y., Vastert, B., Beresford, N., Beresford, M. & Kamphuis, S., 2017, In: Annals of the Rheumatic Diseases. 76, 12, p. 1965-1973 9 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  125 Citations (Scopus)
• 2015

  Case report: an 11-year-old girl presenting with asymptomatic retinal vasculitis leading to diagnosis of HIV-1 infection

  Westland, T., Kamphuis, S., van Rossum, A. & Rothova, A., 2015, In: AIDS. 29, 14, p. 1901-1902 2 p.

  Research output: Contribution to journal › Article › Academic › peer-review

  4 Citations (Scopus)

• CD226 (DNAM-1) is associated with susceptibility to juvenile idiopathic arthritis

  Reinards, T., Albers, H., Brinkman, D., Kamphuis, S., van Rossum, M., Girschick, H., Wouters, C., Hoppenreijs, E., Saurenmann, R., Hinks, A., Ellis, J., Bakker, M., Verduijn, W., Slagboom, P., Huizinga, T., Toes, R., Houwing-Duistermaat, J., ten Cate, R. & Schilham, M., 2015, In: Annals of the Rheumatic Diseases. 74, 12, p. 2193-2198 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  33 Citations (Scopus)

• Methotrexate polyglutamates in erythrocytes are associated with lower disease activity in juvenile idiopathic arthritis patients

  Calasan, M., den Boer, E., de Rotte, M., Vastert, S., Kamphuis, S., de Jonge, R. & Wulffraat, N., 2015, In: Annals of the Rheumatic Diseases. 74, 2, p. 402-407 6 p.

  Research output: Contribution to journal › Article › Academic › peer-review
  46 Citations (Scopus)