3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer

Wouter van Elmpt; Steven Petit; Dirk De Ruysscher; Philippe Lambin; André Dekker

doi:10.1016/j.radonc.2009.12.024

3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer

Wouter van Elmpt, Steven Petit, Dirk De Ruysscher, Philippe Lambin, André Dekker

Research output: Contribution to journal › Article › Academic › peer-review

39 Citations (Scopus)

Abstract

PURPOSE: To implement a 3D dose verification procedure, based on in-room cone-beam CT imaging and portal dosimetry, for lung cancer patients treated with stereotactic body radiotherapy (SBRT).

MATERIALS AND METHODS: MV cone-beam CT scans were made for patient positioning and calibrated for dose calculation purposes. Prior to treatment, the treatment fields were captured using a calibrated electronic portal imaging device (EPID). A Monte Carlo dose reconstruction model was used to estimate the 3D dose delivered to the patient inside the cone-beam CT images. The planned and delivered dose distributions were compared for 4 patients and 10 treatment fractions using dose-volume histograms and gamma analysis.

RESULTS: The gamma analysis showed a good agreement between the planned and delivered dose distributions for patients without changes in anatomy. The delivered mean dose per fraction inside the target volume deviated on average 1.1+/-1.4% from the planned dose. For the critical organs, only minor differences were observed between the reconstructed and planned dose.

CONCLUSIONS: A method was presented that allows verification of the dose delivered in 3D for lung cancer patients treated with SBRT. The procedure is independent of the treatment planning system and uses in-room MV cone-beam CT imaging and portal dosimetry.

Original language	English
Pages (from-to)	188-94
Number of pages	7
Journal	Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology
Volume	94
Issue number	2
DOIs	https://doi.org/10.1016/j.radonc.2009.12.024
Publication status	Published - Feb 2010
Externally published	Yes

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10.1016/j.radonc.2009.12.024

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van Elmpt, W., Petit, S., De Ruysscher, D., Lambin, P., & Dekker, A. (2010). 3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 94(2), 188-94. https://doi.org/10.1016/j.radonc.2009.12.024

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title = "3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer",

abstract = "PURPOSE: To implement a 3D dose verification procedure, based on in-room cone-beam CT imaging and portal dosimetry, for lung cancer patients treated with stereotactic body radiotherapy (SBRT).MATERIALS AND METHODS: MV cone-beam CT scans were made for patient positioning and calibrated for dose calculation purposes. Prior to treatment, the treatment fields were captured using a calibrated electronic portal imaging device (EPID). A Monte Carlo dose reconstruction model was used to estimate the 3D dose delivered to the patient inside the cone-beam CT images. The planned and delivered dose distributions were compared for 4 patients and 10 treatment fractions using dose-volume histograms and gamma analysis.RESULTS: The gamma analysis showed a good agreement between the planned and delivered dose distributions for patients without changes in anatomy. The delivered mean dose per fraction inside the target volume deviated on average 1.1+/-1.4% from the planned dose. For the critical organs, only minor differences were observed between the reconstructed and planned dose.CONCLUSIONS: A method was presented that allows verification of the dose delivered in 3D for lung cancer patients treated with SBRT. The procedure is independent of the treatment planning system and uses in-room MV cone-beam CT imaging and portal dosimetry.",

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van Elmpt, W, Petit, S , De Ruysscher, D, Lambin, P & Dekker, A 2010, '3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer', Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, vol. 94, no. 2, pp. 188-94. https://doi.org/10.1016/j.radonc.2009.12.024

3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer. / van Elmpt, Wouter; Petit, Steven ; De Ruysscher, Dirk et al.
In: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, Vol. 94, No. 2, 02.2010, p. 188-94.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - 3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer

AU - van Elmpt, Wouter

AU - Petit, Steven

AU - De Ruysscher, Dirk

AU - Lambin, Philippe

AU - Dekker, André

PY - 2010/2

Y1 - 2010/2

N2 - PURPOSE: To implement a 3D dose verification procedure, based on in-room cone-beam CT imaging and portal dosimetry, for lung cancer patients treated with stereotactic body radiotherapy (SBRT).MATERIALS AND METHODS: MV cone-beam CT scans were made for patient positioning and calibrated for dose calculation purposes. Prior to treatment, the treatment fields were captured using a calibrated electronic portal imaging device (EPID). A Monte Carlo dose reconstruction model was used to estimate the 3D dose delivered to the patient inside the cone-beam CT images. The planned and delivered dose distributions were compared for 4 patients and 10 treatment fractions using dose-volume histograms and gamma analysis.RESULTS: The gamma analysis showed a good agreement between the planned and delivered dose distributions for patients without changes in anatomy. The delivered mean dose per fraction inside the target volume deviated on average 1.1+/-1.4% from the planned dose. For the critical organs, only minor differences were observed between the reconstructed and planned dose.CONCLUSIONS: A method was presented that allows verification of the dose delivered in 3D for lung cancer patients treated with SBRT. The procedure is independent of the treatment planning system and uses in-room MV cone-beam CT imaging and portal dosimetry.

AB - PURPOSE: To implement a 3D dose verification procedure, based on in-room cone-beam CT imaging and portal dosimetry, for lung cancer patients treated with stereotactic body radiotherapy (SBRT).MATERIALS AND METHODS: MV cone-beam CT scans were made for patient positioning and calibrated for dose calculation purposes. Prior to treatment, the treatment fields were captured using a calibrated electronic portal imaging device (EPID). A Monte Carlo dose reconstruction model was used to estimate the 3D dose delivered to the patient inside the cone-beam CT images. The planned and delivered dose distributions were compared for 4 patients and 10 treatment fractions using dose-volume histograms and gamma analysis.RESULTS: The gamma analysis showed a good agreement between the planned and delivered dose distributions for patients without changes in anatomy. The delivered mean dose per fraction inside the target volume deviated on average 1.1+/-1.4% from the planned dose. For the critical organs, only minor differences were observed between the reconstructed and planned dose.CONCLUSIONS: A method was presented that allows verification of the dose delivered in 3D for lung cancer patients treated with SBRT. The procedure is independent of the treatment planning system and uses in-room MV cone-beam CT imaging and portal dosimetry.

U2 - 10.1016/j.radonc.2009.12.024

DO - 10.1016/j.radonc.2009.12.024

M3 - Article

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SN - 0167-8140

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JO - Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

JF - Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology

IS - 2

ER -

3D dose delivery verification using repeated cone-beam imaging and EPID dosimetry for stereotactic body radiotherapy of non-small cell lung cancer

Abstract

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