3D genomics:: form and function of chromatin

Robin van der Weide

3D genomics: form and function of chromatin

Robin van der Weide

Cell biology

Research output: Types of Thesis › Doctoral Thesis › Internal

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Abstract

DNA is stored in the nucleus of every cell in the same way, but how is this done? We show that the Cohesin-complex plays a major role in the formation and maintenance of chromatin-loops and that this affects multiple layers of gene-regulation.

Original language	English
Awarding Institution	Erasmus University Rotterdam
Supervisors/Advisors	van Steensel, Bas, Supervisor de Wit, Elzo, Co-supervisor
Award date	17 Mar 2022
Place of Publication	Rotterdam
Print ISBNs	978-94-6458-016-7
Publication status	Published - 17 Mar 2022

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final dissertation WeideFinal published version, 56.1 MBLicence: Unspecified

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title = "3D genomics:: form and function of chromatin",

abstract = "DNA is stored in the nucleus of every cell in the same way, but how is this done? We show that the Cohesin-complex plays a major role in the formation and maintenance of chromatin-loops and that this affects multiple layers of gene-regulation.",

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T2 - form and function of chromatin

AU - van der Weide, Robin

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Y1 - 2022/3/17

N2 - DNA is stored in the nucleus of every cell in the same way, but how is this done? We show that the Cohesin-complex plays a major role in the formation and maintenance of chromatin-loops and that this affects multiple layers of gene-regulation.

AB - DNA is stored in the nucleus of every cell in the same way, but how is this done? We show that the Cohesin-complex plays a major role in the formation and maintenance of chromatin-loops and that this affects multiple layers of gene-regulation.

M3 - Doctoral Thesis

SN - 978-94-6458-016-7

CY - Rotterdam

ER -

3D genomics: form and function of chromatin

Abstract

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