7 The emergence of networks in human genome epidemiology: Challenges and opportunities

Daniela Seminara*, Muin J. Khoury, Thomas R. O'brien, Teri Manolio, Marta Gwinn, Julian Little, Julian P.T. Higgins, Jonine L. Bernstein, Paolo Boffetta, Melissa L. Bondy, Molly S. Bray, Paul E. Brenchley, Patricia A. Buffler, Juan Pablo Casas, Anand P. Chokkalingam, John Danesh, George Davey Smith, Siobhan M. Dolan, Ross Duncan, Nelleke A. GruisMia Hashibe, David J. Hunter, Marjo Riitta Jarvelin, Beatrice Malmer, Demetrius M. Maraganore, Julia A. Newton-Bishop, Elio Riboli, Georgia Salanti, Emanuela Taioli, Nic Timpson, André G. Uitterlinden, Paolo Vineis, Nick Wareham, Deborah M. Winn, Ron Zimmern, John P.A. Ioannidis

*Corresponding author for this work

Research output: Chapter/Conference proceedingChapterAcademic

Abstract

The Human Genome Epidemiology Network (HuGENet) recently launched a global network of consortia working on human genome epidemiology. This Network of Investigator Networks aims to create a resource to share information, offer methodologic support, generate inclusive overviews of studies conducted in specific fields, and to facilitate rapid confirmation of findings. In October 2005, HuGENet brought together representatives from established and emerging networks in order to share their experiences at a workshop in Cambridge, United Kingdom. In advance of the meeting, a qualitative questionnaire was distributed to workshop participants. The questionnaire elicited information on experiences and practices in building and maintaining consortia. This chapter reports on the numerous challenges and their possible solutions as identified by the workshop participants, as well as new opportunities offered by the network approach to genetic and genomic epidemiology.

Original languageEnglish
Title of host publicationHuman Genome Epidemiology
Subtitle of host publicationBuilding the Evidence for Using Genetic Information to Improve Health and Prevent Disease
Chapter7
Pages120-135
Edition Second Edition
ISBN (Electronic)9780199776023
DOIs
Publication statusPublished - 1 May 2010

Bibliographical note

Publisher Copyright: © Oxford University Press, 2014.

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  • The emergence of networks in human genome epidemiology - Challenges and opportunities

    Seminara, D., Khoury, MJ., O'Brien, TR., Manolio, T., Gwinn, ML., Little, J., T Higgins, JP., Bernstein, JL., Boffetta, P., Bondy, M., Bray, MS., Brenchley, PE., Buffler, PA., Casas, JP., Chokkalingam, AP., Danesh, J., Smith, GD., Dolan, S., Duncan, R., Gruis, NA., & 16 othersHashibe, M., Hunter, D., Jarvelin, MR., Malmer, B., Maraganore, DM., Newton-Bishop, JA., Riboli, E., Salanti, G., Taioli, E., Timpson, N., Uitterlinden, A., Vineis, P., Wareham, N., Winn, DM., Zimmern, R. & Ioannidis, JPA., 2007, In: Epidemiology. 18, 1, p. 1-8 8 p.

    Research output: Contribution to journalArticleAcademicpeer-review

    79 Citations (Scopus)

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