A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies

GA Cirkel; B M Kerklaan; F Vanhoutte; A Van der Aa; G Lorenzon; F Namour; P Pujuguet; S Darquenne; FYF de Vos; TJ Snijders; EE Voest; JHM Schellens; Martijn Lolkema

doi:10.1007/s10637-015-0320-9

A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies

GA Cirkel, B M Kerklaan, F Vanhoutte, A Van der Aa, G Lorenzon, F Namour, P Pujuguet, S Darquenne, FYF de Vos, TJ Snijders, EE Voest, JHM Schellens, Martijn Lolkema

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

38 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	184-192
Number of pages	9
Journal	Investigational New Drugs
Volume	34
Issue number	2
DOIs	https://doi.org/10.1007/s10637-015-0320-9
Publication status	Published - 2016

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10.1007/s10637-015-0320-9

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Cirkel, GA., Kerklaan, B. M., Vanhoutte, F., Van der Aa, A., Lorenzon, G., Namour, F., Pujuguet, P., Darquenne, S., de Vos, FYF., Snijders, TJ., Voest, EE., Schellens, JHM., & Lolkema, M. (2016). A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies. Investigational New Drugs, 34(2), 184-192. https://doi.org/10.1007/s10637-015-0320-9

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author = "GA Cirkel and Kerklaan, {B M} and F Vanhoutte and {Van der Aa}, A and G Lorenzon and F Namour and P Pujuguet and S Darquenne and {de Vos}, FYF and TJ Snijders and EE Voest and JHM Schellens and Martijn Lolkema",

year = "2016",

doi = "10.1007/s10637-015-0320-9",

language = "Undefined/Unknown",

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pages = "184--192",

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Cirkel, GA, Kerklaan, BM, Vanhoutte, F, Van der Aa, A, Lorenzon, G, Namour, F, Pujuguet, P, Darquenne, S, de Vos, FYF, Snijders, TJ, Voest, EE, Schellens, JHM & Lolkema, M 2016, 'A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies', Investigational New Drugs, vol. 34, no. 2, pp. 184-192. https://doi.org/10.1007/s10637-015-0320-9

A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies. / Cirkel, GA; Kerklaan, B M; Vanhoutte, F et al.
In: Investigational New Drugs, Vol. 34, No. 2, 2016, p. 184-192.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A dose escalating phase I study of GLPG0187, a broad spectrum integrin receptor antagonist, in adult patients with progressive high-grade glioma and other advanced solid malignancies

AU - Cirkel, GA

AU - Kerklaan, B M

AU - Vanhoutte, F

AU - Van der Aa, A

AU - Lorenzon, G

AU - Namour, F

AU - Pujuguet, P

AU - Darquenne, S

AU - de Vos, FYF

AU - Snijders, TJ

AU - Voest, EE

AU - Schellens, JHM

AU - Lolkema, Martijn

PY - 2016

Y1 - 2016

U2 - 10.1007/s10637-015-0320-9

DO - 10.1007/s10637-015-0320-9

M3 - Article

SN - 0167-6997

VL - 34

SP - 184

EP - 192

JO - Investigational New Drugs

JF - Investigational New Drugs

IS - 2

ER -