A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

Raymond Noordam; CM Sitlani; CL Avery; JD Stewart; SM Gogarten; KL Wiggins; S Trompet; HR Warren; FG Sun; DS Evans; XH Li; J Li; AV Smith; JC Bis; JA Brody; EL Busch; MJ Caulfield; YDI Chen; SR Cummings; LA Cupples; Q Duan; OH Franco Duran; R Mendez-Giraldez; TB Harris; SR Heckbert; D van Heemst; Bert Hofman; J S Floyd; Jan Kors; LJ Launer; Y Li; RF Li-Gao; LA Lange; H J Lin; R de Mutsert; MD Napier; C Newton-Cheh; N Poulter; AP Reiner; KM Rice; J Roach; C J Rodriguez; FR Rosendaal; N Sattar; P Sever; AA Seyerle; PE (Eline) Slagboom; EZ Soliman; N Sotoodehnia; DJ Stott; T Stumer; KD Taylor; TA Thornton; André Uitterlinden; KC Wilhelmsen; JG Wilson; V Gudnason; JW Jukema; CC Laurie; Y Liu; DO Mook-Kanamori; PB Munroe; JI Rotter; RS Vasan; BM Psaty; Bruno Stricker; EA Whitsel

doi:10.1136/jmedgenet-2016-104112

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

Raymond Noordam
, CM Sitlani
, CL Avery
, JD Stewart
, SM Gogarten
, KL Wiggins
, S Trompet
, HR Warren
, FG Sun
, DS Evans
, XH Li
, J Li
, AV Smith
, JC Bis
, JA Brody
, EL Busch
, MJ Caulfield
, YDI Chen
, SR Cummings
, LA Cupples

Q Duan, OH Franco Duran, R Mendez-Giraldez, TB Harris, SR Heckbert, D van Heemst, Bert Hofman, J S Floyd, Jan Kors, LJ Launer, Y Li, RF Li-Gao, LA Lange, H J Lin, R de Mutsert, MD Napier, C Newton-Cheh, N Poulter, AP Reiner, KM Rice, J Roach, C J Rodriguez, FR Rosendaal, N Sattar, P Sever, AA Seyerle, PE (Eline) Slagboom, EZ Soliman, N Sotoodehnia, DJ Stott, T Stumer, KD Taylor, TA Thornton, André Uitterlinden, KC Wilhelmsen, JG Wilson, V Gudnason, JW Jukema, CC Laurie, Y Liu, DO Mook-Kanamori, PB Munroe, JI Rotter, RS Vasan, BM Psaty, Bruno Stricker, EA Whitsel

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	313-323
Number of pages	11
Journal	Journal of Medical Genetics
Volume	54
Issue number	5
DOIs	https://doi.org/10.1136/jmedgenet-2016-104112
Publication status	Published - 2017

Research programs

EMC OR-01

Access to Document

10.1136/jmedgenet-2016-104112

http://hdl.handle.net/1765/95691

Cite this

Noordam, R., Sitlani, CM., Avery, CL., Stewart, JD., Gogarten, SM., Wiggins, KL., Trompet, S., Warren, HR., Sun, FG., Evans, DS., Li, XH., Li, J., Smith, AV., Bis, JC., Brody, JA., Busch, EL., Caulfield, MJ., Chen, YDI., Cummings, SR., ... Whitsel, EA. (2017). A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics, 54(5), 313-323. https://doi.org/10.1136/jmedgenet-2016-104112

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title = "A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium",

author = "Raymond Noordam and CM Sitlani and CL Avery and JD Stewart and SM Gogarten and KL Wiggins and S Trompet and HR Warren and FG Sun and DS Evans and XH Li and J Li and AV Smith and JC Bis and JA Brody and EL Busch and MJ Caulfield and YDI Chen and SR Cummings and LA Cupples and Q Duan and \{Franco Duran\}, OH and R Mendez-Giraldez and TB Harris and SR Heckbert and \{van Heemst\}, D and Bert Hofman and Floyd, \{J S\} and Jan Kors and LJ Launer and Y Li and RF Li-Gao and LA Lange and Lin, \{H J\} and \{de Mutsert\}, R and MD Napier and C Newton-Cheh and N Poulter and AP Reiner and KM Rice and J Roach and Rodriguez, \{C J\} and FR Rosendaal and N Sattar and P Sever and AA Seyerle and Slagboom, \{PE (Eline)\} and EZ Soliman and N Sotoodehnia and DJ Stott and T Stumer and KD Taylor and TA Thornton and Andr{\'e} Uitterlinden and KC Wilhelmsen and JG Wilson and V Gudnason and JW Jukema and CC Laurie and Y Liu and DO Mook-Kanamori and PB Munroe and JI Rotter and RS Vasan and BM Psaty and Bruno Stricker and EA Whitsel",

year = "2017",

doi = "10.1136/jmedgenet-2016-104112",

language = "Undefined/Unknown",

volume = "54",

pages = "313--323",

journal = "Journal of Medical Genetics",

issn = "0022-2593",

publisher = "BMJ Publishing Group",

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}

Noordam, R, Sitlani, CM, Avery, CL, Stewart, JD, Gogarten, SM, Wiggins, KL, Trompet, S, Warren, HR, Sun, FG, Evans, DS, Li, XH, Li, J, Smith, AV, Bis, JC, Brody, JA, Busch, EL, Caulfield, MJ, Chen, YDI, Cummings, SR, Cupples, LA, Duan, Q, Franco Duran, OH, Mendez-Giraldez, R, Harris, TB, Heckbert, SR, van Heemst, D, Hofman, B, Floyd, JS, Kors, J, Launer, LJ, Li, Y, Li-Gao, RF, Lange, LA, Lin, HJ, de Mutsert, R, Napier, MD, Newton-Cheh, C, Poulter, N, Reiner, AP, Rice, KM, Roach, J, Rodriguez, CJ, Rosendaal, FR, Sattar, N, Sever, P, Seyerle, AA, Slagboom, PE, Soliman, EZ, Sotoodehnia, N, Stott, DJ, Stumer, T, Taylor, KD, Thornton, TA, Uitterlinden, A, Wilhelmsen, KC, Wilson, JG, Gudnason, V, Jukema, JW, Laurie, CC, Liu, Y, Mook-Kanamori, DO, Munroe, PB, Rotter, JI, Vasan, RS, Psaty, BM, Stricker, B & Whitsel, EA 2017, 'A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium', Journal of Medical Genetics, vol. 54, no. 5, pp. 313-323. https://doi.org/10.1136/jmedgenet-2016-104112

A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. / Noordam, Raymond; Sitlani, CM; Avery, CL et al.
In: Journal of Medical Genetics, Vol. 54, No. 5, 2017, p. 313-323.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium

AU - Noordam, Raymond

AU - Sitlani, CM

AU - Avery, CL

AU - Stewart, JD

AU - Gogarten, SM

AU - Wiggins, KL

AU - Trompet, S

AU - Warren, HR

AU - Sun, FG

AU - Evans, DS

AU - Li, XH

AU - Li, J

AU - Smith, AV

AU - Bis, JC

AU - Brody, JA

AU - Busch, EL

AU - Caulfield, MJ

AU - Chen, YDI

AU - Cummings, SR

AU - Cupples, LA

AU - Duan, Q

AU - Franco Duran, OH

AU - Mendez-Giraldez, R

AU - Harris, TB

AU - Heckbert, SR

AU - van Heemst, D

AU - Hofman, Bert

AU - Floyd, J S

AU - Kors, Jan

AU - Launer, LJ

AU - Li, Y

AU - Li-Gao, RF

AU - Lange, LA

AU - Lin, H J

AU - de Mutsert, R

AU - Napier, MD

AU - Newton-Cheh, C

AU - Poulter, N

AU - Reiner, AP

AU - Rice, KM

AU - Roach, J

AU - Rodriguez, C J

AU - Rosendaal, FR

AU - Sattar, N

AU - Sever, P

AU - Seyerle, AA

AU - Slagboom, PE (Eline)

AU - Soliman, EZ

AU - Sotoodehnia, N

AU - Stott, DJ

AU - Stumer, T

AU - Taylor, KD

AU - Thornton, TA

AU - Uitterlinden, André

AU - Wilhelmsen, KC

AU - Wilson, JG

AU - Gudnason, V

AU - Jukema, JW

AU - Laurie, CC

AU - Liu, Y

AU - Mook-Kanamori, DO

AU - Munroe, PB

AU - Rotter, JI

AU - Vasan, RS

AU - Psaty, BM

AU - Stricker, Bruno

AU - Whitsel, EA

PY - 2017

Y1 - 2017

U2 - 10.1136/jmedgenet-2016-104112

DO - 10.1136/jmedgenet-2016-104112

M3 - Article

C2 - 28039329

SN - 0022-2593

VL - 54

SP - 313

EP - 323

JO - Journal of Medical Genetics

JF - Journal of Medical Genetics

IS - 5

ER -

Noordam R, Sitlani CM, Avery CL, Stewart JD, Gogarten SM, Wiggins KL et al. A genome-wide interaction analysis of tricyclic/tetracyclic antidepressants and RR and QT intervals: a pharmacogenomics study from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortium. Journal of Medical Genetics. 2017;54(5):313-323. doi: 10.1136/jmedgenet-2016-104112