A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

RA Scott, DF Freitag, Li Li, AY Chu, P Surendran, R Young, N Grarup, A Stancakova, YN Chen, TV Varga, H Yaghootkar, JA Luan, JH Zhao, SM Willems, J Wessel, S Wang, N Maruthur, K Michailidou, A Pirie, Sven van der LeeC Gillson, A A Al Olama, P Amouyel, L Arriola, D Arveiler, I Aviles-Olmos, B Balkau, A Barricarte, I Barroso, S B Garcia, JC Bis, S Blankenberg, M Boehnke, H Boeing, E Boerwinkle, IB Borecki, J Bork-Jensen, S Bowden, C Caldas, M Caslake, LA Cupples, C Cruchaga, J Czajkowski, M den Hoed, JA Dunn, HM Earl, GB Ehret, E Ferrannini, J Ferrieres, T Foltynie, I Ford, NG Forouhi, F Gianfagna, C Gonzalez, S Grioni, L Hiller, JH Jansson, ME Jorgensen, JW Jukema, R Kaaks, F Kee, ND Kerrison, TJ Key, J Kontto, Z Kote-Jarai, AT Kraja, K Kuulasmaa, J Kuusisto, A Linneberg, CY Liu, G Marenne, KL Mohlke, AP Morris, K Muir, M Muller-Nurasyid, PB Munroe, C Navarro, SF Nielsen, PM Nilsson, BG Nordestgaard, CJ Packard, D Palli, S Panico, GM Peloso, M Perola, A Peters, CJ Poole, JR Quiros, O Rolandsson, C Sacerdote, V Salomaa, MJ Sanchez, N Sattar, SJ Sharp, R Sims, N Slimani, JA Smith, DJ Thompson, S Trompet, R Tumino, DL van der A, YT van der Schouw, J Virtamo, M Walker, K Walter, JE Abraham, L T Amundadottir, JL Aponte, A Butterworth, J Dupuis, DF Easton, RA Eeles, J Erdmann, PW Franks, TM Frayling, T Hansen, JMM Howson, T Jorgensen, J Kooner, M Laakso, C Langenberg, MI McCarthy, JS Pankow, O Pedersen, E Riboli, JI Rotter, D Saleheen, NJ Samani, H Schunkert, P Vollenweider, S O'Rahilly, P Deloukas, J Danesh, MO Goodarzi, S Kathiresan, JB Meigs, MG Ehm, NJ Wareham, DM Waterworth

Research output: Contribution to journalArticleAcademicpeer-review

75 Citations (Scopus)
Original languageUndefined/Unknown
Article number341ra76
JournalScience Translational Medicine
Volume8
Issue number341
DOIs
Publication statusPublished - 2016

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