A hierarchical model for the relationships between general and specific vulnerability factors and symptom levels of generalized anxiety disorder

C van der Heiden*, K (Frauke) Melchior, PEHM Muris, Samantha Bouwmeester, AER (Arjan) Bos, Henk van der Molen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

68 Citations (Scopus)

Abstract

The present study examined a hierarchical model for the relationships between general and specific vulnerability factors and symptom manifestations of generalized anxiety disorder (GAD). A clinical sample of patients with GAD (N=137) completed a set of self-report questionnaires for measuring neuroticism, extraversion, intolerance of uncertainty, metacognitive beliefs, and symptoms of generalized anxiety (i.e., worry) and depression. A bootstrapping analysis yielded support for a model in which the relation between the general vulnerability factor of neuroticism and symptoms of GAD were mediated by the specific vulnerability factors of intolerance of uncertainty and negative metacognitions. Implications for the classification and treatment of GAD are discussed.

Original languageEnglish
Pages (from-to)284-289
Number of pages5
JournalJournal of Anxiety Disorders
Volume24
Issue number2
DOIs
Publication statusPublished - Mar 2010

Bibliographical note

Copyright 2009 Elsevier Ltd. All rights reserved.

Research programs

  • ESSB PSY

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