A man with brown spots

Kelly A.A. Kwa, Kees Peter de Roos

Research output: Contribution to journalArticleAcademicpeer-review


A 58-year-old man presents with spontaneous brown discolorations of his mouth and hands. Our differential diagnosis included Peutz-Jeghers syndrome, Laugier-Hunziker syndrome or Addison's disease. There were no polyps in a previously performed colonoscopy and no other systemic symptoms. We made the diagnosis Laugier-Hunziker syndrome, a benign skin disorder that doesn't require treatment, confirmed by skin biopsy.

Original languageEnglish
Article numberD7681
JournalNederlands Tijdschrift voor Geneeskunde
Issue number43
Publication statusPublished - 23 Oct 2023

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