A New Approach to Evidence Synthesis in Traumatic Brain Injury: A Living Systematic Review

Anneliese Synnot*, Russell L. Gruen, David Menon, Ewout W. Steyerberg, Andras Buki, Wilco C. Peul, Julian H. Elliott, Andrew Maas

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

4 Citations (Scopus)
11 Downloads (Pure)


Living systematic reviews (LSRs) are online summaries of health care research that are updated as new research becomes available. This new development in evidence synthesis is being trialled as part of the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) project. We will develop and sustain an international TBI knowledge community that maintains up-to-date, high quality LSRs of the current state of knowledge in the most important questions in TBI. Automatic search updates will be run three-monthly, and newly identified studies incorporated into the review. Review teams will seek to publish journal updates at regular intervals, with abridged updates available more frequently online. Future project stages include the integration of LSR and other study findings into "living"clinical practice guidance. It is hoped these efforts will go some way to bridging current temporal disconnects between evidence, guidelines, and practice in TBI.

Original languageEnglish
Pages (from-to)1069-1071
Number of pages3
JournalJournal of Neurotrauma
Issue number8
Early online date15 Apr 2021
Publication statusPublished - 2021

Bibliographical note

This work was supported by the European Union FP 7thFramework program (grant 602150). The authors acknowl-edge Professor Sally Green for her valuable comments on themanuscript.

Publisher Copyright:
© Anneliese Synnot et al. 2016; Published by Mary Ann Liebert, Inc. 2016.


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