A phase I pharmacokinetic and pharmacodynamic study of the farnesyl transferase inhibitor BMS-214662 in combination with cisplatin in patients with advanced solid tumors

HJ Mackay; R (Rosa) Hoekstra; Ferry Eskens; Walter Loos; D Crawford; M Voi; A van Vreckem; TRJ Evans; Jaap Verweij

doi:10.1158/1078-0432.CCR-03-0327

A phase I pharmacokinetic and pharmacodynamic study of the farnesyl transferase inhibitor BMS-214662 in combination with cisplatin in patients with advanced solid tumors

HJ Mackay
, R (Rosa) Hoekstra
, Ferry Eskens
, Walter Loos
, D Crawford
, M Voi
, A van Vreckem
, TRJ Evans
, Jaap Verweij

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

22 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	2636-2644
Number of pages	9
Journal	Clinical Cancer Research
Volume	10
DOIs	https://doi.org/10.1158/1078-0432.CCR-03-0327
Publication status	Published - 2004

Research programs

EMC MM-03-86-08

Access to Document

10.1158/1078-0432.CCR-03-0327

http://hdl.handle.net/1765/55227

Cite this

Mackay, HJ., Hoekstra, R., Eskens, F., Loos, W., Crawford, D., Voi, M., van Vreckem, A., Evans, TRJ., & Verweij, J. (2004). A phase I pharmacokinetic and pharmacodynamic study of the farnesyl transferase inhibitor BMS-214662 in combination with cisplatin in patients with advanced solid tumors. Clinical Cancer Research, 10, 2636-2644. https://doi.org/10.1158/1078-0432.CCR-03-0327

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Mackay, HJ, Hoekstra, R, Eskens, F, Loos, W, Crawford, D, Voi, M, van Vreckem, A, Evans, TRJ & Verweij, J 2004, 'A phase I pharmacokinetic and pharmacodynamic study of the farnesyl transferase inhibitor BMS-214662 in combination with cisplatin in patients with advanced solid tumors', Clinical Cancer Research, vol. 10, pp. 2636-2644. https://doi.org/10.1158/1078-0432.CCR-03-0327

TY - JOUR

T1 - A phase I pharmacokinetic and pharmacodynamic study of the farnesyl transferase inhibitor BMS-214662 in combination with cisplatin in patients with advanced solid tumors

AU - Mackay, HJ

AU - Hoekstra, R (Rosa)

AU - Eskens, Ferry

AU - Loos, Walter

AU - Crawford, D

AU - Voi, M

AU - van Vreckem, A

AU - Evans, TRJ

AU - Verweij, Jaap

PY - 2004

Y1 - 2004

U2 - 10.1158/1078-0432.CCR-03-0327

DO - 10.1158/1078-0432.CCR-03-0327

M3 - Article

SN - 1078-0432

VL - 10

SP - 2636

EP - 2644

JO - Clinical Cancer Research

JF - Clinical Cancer Research

ER -