A roadmap to disentangle the molecular etiology of schizophrenia

Peter Falkai*, Owen Mike, Myin Germeys Inez, Harrison Paul, Bilkei Gorzo Andras, Frangou Sophia, Consortium MEOS Consortium, Frangou Sophia, Bilkei Gorzo Andras, Bitter István, Crespo Facorro Benedicto, Marc De Hert, Dierks Thomas, Annabella Di Giorgio, Germeys Inez, Gjedde Albert, Paul J. Harrison, Kasper Siegfried, Lawrie Stephen, Leboyer MarionMaier Wolfgang, Maron Eduard, Philip McGuire, Meyer Lindenberg Andreas, Nöthen Markus, Owen Mike, Ruhrmann Stephan, Schürhoff Franck, Shifman Sagiv, Stefanis Nicholas, Neeltje van Haren, Vaudano Elisabett, Vita Antonio

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

7 Citations (Scopus)

Abstract

Schizophrenia is a severe mental disorder striking mainly young adults and leading to life-long disability in a substantial portion of the sufferers. On the other hand, substantial knowledge about its etiology and pathogenesis is still lacking. Therefore the European Science Foundation (ESF) sponsored a meeting of a panel of European experts on schizophrenia research to discuss the state of art and future perspectives of key topics in this area. The fields covered genetics, epidemiology, animal models, molecular neuropathology and imaging. This was a first step to establish a network of European groups dedicated to Schizophrenia research. The coming calls of the frame work program will be used to strengthen this network in order to achieve substantial progress in understanding and treating this devastating illness.

Original languageEnglish
Pages (from-to)224-232
Number of pages9
JournalEuropean Psychiatry
Volume23
Issue number4
DOIs
Publication statusPublished - 1 Jun 2008
Externally publishedYes

Bibliographical note

Funding Information:
Two calls of the 6FTP-EU initiated intense activity among those European groups with a major interest in schizophrenia research. Several grant proposals were submitted but only the one around DECODE was funded. Subsequently a workshop sponsored by the European Science Foundation (ESF) took place at the Institute of Psychiatry in London at 26th of October 2007. During the 1 day workshop the topics genetics, epidemiology, molecular neuropathology, animal models and imaging were discussed. For each topic, one leading expert gave a 15-min introduction trying to answer the following questions within their special area of interest:

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