Accessible and reliable neurometric testing in humans using a smartphone platform

H. J. Boele; C. Jung; S. Sherry; L. E.M. Roggeveen; S. Dijkhuizen; J. Öhman; E. Abraham; A. Uvarov; C. P. Boele; K. Gultig; A. Rasmussen; M. F. Vinueza-Veloz; J. F. Medina; S. K.E. Koekkoek; C. I. De Zeeuw; S. S.H. Wang

doi:10.1038/s41598-023-49568-2

Accessible and reliable neurometric testing in humans using a smartphone platform

H. J. Boele^*, C. Jung, S. Sherry, L. E.M. Roggeveen, S. Dijkhuizen, J. Öhman, E. Abraham, A. Uvarov, C. P. Boele, K. Gultig, A. Rasmussen, M. F. Vinueza-Veloz, J. F. Medina, S. K.E. Koekkoek, C. I. De Zeeuw, S. S.H. Wang^*

^*Corresponding author for this work

Neurosciences

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Abstract

Tests of human brain circuit function typically require fixed equipment in lab environments. We have developed a smartphone-based platform for neurometric testing. This platform, which uses AI models like computer vision, is optimized for at-home use and produces reproducible, robust results on a battery of tests, including eyeblink conditioning, prepulse inhibition of acoustic startle response, and startle habituation. This approach provides a scalable, universal resource for quantitative assays of central nervous system function.

Original language	English
Article number	22871
Journal	Scientific Reports
Volume	13
Issue number	1
DOIs	https://doi.org/10.1038/s41598-023-49568-2
Publication status	Published - 18 Dec 2023

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© 2023, The Author(s).

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Accessible and reliable neurometric testing in humans using a smartphone platformFinal published version, 2.39 MBLicence: CC BY

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Boele, H. J., Jung, C., Sherry, S., Roggeveen, L. E. M., Dijkhuizen, S., Öhman, J., Abraham, E., Uvarov, A., Boele, C. P., Gultig, K., Rasmussen, A., Vinueza-Veloz, M. F., Medina, J. F., Koekkoek, S. K. E., De Zeeuw, C. I., & Wang, S. S. H. (2023). Accessible and reliable neurometric testing in humans using a smartphone platform. Scientific Reports, 13(1), Article 22871. https://doi.org/10.1038/s41598-023-49568-2

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Boele, HJ, Jung, C, Sherry, S, Roggeveen, LEM, Dijkhuizen, S, Öhman, J, Abraham, E, Uvarov, A, Boele, CP, Gultig, K, Rasmussen, A, Vinueza-Veloz, MF, Medina, JF, Koekkoek, SKE , De Zeeuw, CI & Wang, SSH 2023, 'Accessible and reliable neurometric testing in humans using a smartphone platform', Scientific Reports, vol. 13, no. 1, 22871. https://doi.org/10.1038/s41598-023-49568-2

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AU - Boele, H. J.

AU - Jung, C.

AU - Sherry, S.

AU - Roggeveen, L. E.M.

AU - Dijkhuizen, S.

AU - Öhman, J.

AU - Abraham, E.

AU - Uvarov, A.

AU - Boele, C. P.

AU - Gultig, K.

AU - Rasmussen, A.

AU - Vinueza-Veloz, M. F.

AU - Medina, J. F.

AU - Koekkoek, S. K.E.

AU - De Zeeuw, C. I.

AU - Wang, S. S.H.

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Accessible and reliable neurometric testing in humans using a smartphone platform

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