Adaptations in the glucose metabolism of procyclic Trypanosoma brucei isolates from tsetse flies and during differentiation of bloodstream forms

Koen W.A. Van Grinsven, Jan Van Den Abbeele, Peter Van Den Bossche, Jaap J. Van Hellemond, Aloysius G.M. Tielens

Research output: Contribution to journalArticleAcademicpeer-review

28 Citations (Scopus)

Abstract

Procyclic forms of Trypanosoma brucei isolated from the midguts of infected tsetse flies, or freshly transformed from a strain that is close to field isolates, do not use a complete Krebs cycle. Furthermore, short stumpy bloodstream forms produce acetate and are apparently metabolically preadapted to adequate functioning in the tsetse fly.

Original languageEnglish
Pages (from-to)1307-1311
Number of pages5
JournalEukaryotic Cell
Volume8
Issue number8
DOIs
Publication statusPublished - Aug 2009

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