Added Value of Use of a Purified Protein Derivative-Based EnzymeLinked Immunosorbent Spot Assay for Patients with Mycobacterium bovis BCG Infection after Intravesical BCG Instillations

Karen A.  Heemstra; Ailko W J  Bossink; Roan  Spermon; John J. M.  Bouwman; Robert Van Der Kieft; Steven Thijsen

doi:10.1128/CVI.05597-11

Added Value of Use of a Purified Protein Derivative-Based EnzymeLinked Immunosorbent Spot Assay for Patients with Mycobacterium bovis BCG Infection after Intravesical BCG Instillations

Karen A. Heemstra^*
, Ailko W J Bossink
, Roan Spermon
, John J. M. Bouwman
, Robert Van Der Kieft
, Steven Thijsen

^*Corresponding author for this work

Diakonessenhuis Utrecht

Research output: Contribution to journal › Article › Academic › peer-review

4 Citations (Scopus)

Abstract

In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD) as a stimulating antigen was able to demonstrate PPD-specific immune activation. This may help to improve the adequate diagnosis of (systemic) Mycobacterium bovis BCG infections after intravesical BCG instillations for bladder carcinoma.

Original language	English
Number of pages	4
Journal	Clinical and Vaccine Immunology
Volume	19
Issue number	6
DOIs	https://doi.org/10.1128/CVI.05597-11
Publication status	Published - Jun 2012
Externally published	Yes

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Heemstra, K. A., Bossink, A. W. J., Spermon, R., Bouwman, J. J. M., Van Der Kieft, R., & Thijsen, S. (2012). Added Value of Use of a Purified Protein Derivative-Based EnzymeLinked Immunosorbent Spot Assay for Patients with Mycobacterium bovis BCG Infection after Intravesical BCG Instillations. Clinical and Vaccine Immunology, 19(6). https://doi.org/10.1128/CVI.05597-11

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abstract = "In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD) as a stimulating antigen was able to demonstrate PPD-specific immune activation. This may help to improve the adequate diagnosis of (systemic) Mycobacterium bovis BCG infections after intravesical BCG instillations for bladder carcinoma.",

author = "Heemstra, \{Karen A.\} and Bossink, \{Ailko W J\} and Roan Spermon and Bouwman, \{John J. M.\} and \{Van Der Kieft\}, Robert and Steven Thijsen",

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journal = "Clinical and Vaccine Immunology",

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Added Value of Use of a Purified Protein Derivative-Based EnzymeLinked Immunosorbent Spot Assay for Patients with Mycobacterium bovis BCG Infection after Intravesical BCG Instillations. / Heemstra, Karen A. ; Bossink, Ailko W J ; Spermon, Roan et al.
In: Clinical and Vaccine Immunology, Vol. 19, No. 6, 06.2012.

Research output: Contribution to journal › Article › Academic › peer-review

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AU - Heemstra, Karen A.

AU - Bossink, Ailko W J

AU - Spermon, Roan

AU - Bouwman, John J. M.

AU - Van Der Kieft, Robert

AU - Thijsen, Steven

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AB - In this case series, we describe four cases in which the use of gamma interferon release assays with purified protein derivative (PPD) as a stimulating antigen was able to demonstrate PPD-specific immune activation. This may help to improve the adequate diagnosis of (systemic) Mycobacterium bovis BCG infections after intravesical BCG instillations for bladder carcinoma.

U2 - 10.1128/CVI.05597-11

DO - 10.1128/CVI.05597-11

M3 - Article

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VL - 19

JO - Clinical and Vaccine Immunology

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IS - 6

ER -

Added Value of Use of a Purified Protein Derivative-Based EnzymeLinked Immunosorbent Spot Assay for Patients with Mycobacterium bovis BCG Infection after Intravesical BCG Instillations

Abstract

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