Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families

IMM Lakeman; FS Hilbers; M Rodríguez-Girondo; A Lee; MPG Vreeswijk; Antoinette Hollestelle; Caroline Seynaeve; H Meijers-Heijboer; JC Oosterwijk; N Hoogerbrugge; E Olah; HFA Vasen; CJ van Asperen; P Devilee

doi:10.1136/jmedgenet-2019-106072

Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families

IMM Lakeman, FS Hilbers, M Rodríguez-Girondo, A Lee, MPG Vreeswijk, Antoinette Hollestelle, Caroline Seynaeve, H Meijers-Heijboer, JC Oosterwijk, N Hoogerbrugge, E Olah, HFA Vasen, CJ van Asperen, P Devilee

Medical Oncology

Research output: Contribution to journal › Article › Academic › peer-review

43 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	581-589
Number of pages	9
Journal	Journal of Medical Genetics
Volume	56
Issue number	9
DOIs	https://doi.org/10.1136/jmedgenet-2019-106072
Publication status	Published - 2019

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EMC MM-03-86-01

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10.1136/jmedgenet-2019-106072

Cite this

Lakeman, IMM., Hilbers, FS., Rodríguez-Girondo, M., Lee, A., Vreeswijk, MPG., Hollestelle, A., Seynaeve, C., Meijers-Heijboer, H., Oosterwijk, JC., Hoogerbrugge, N., Olah, E., Vasen, HFA., van Asperen, CJ., & Devilee, P. (2019). Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families. Journal of Medical Genetics, 56(9), 581-589. https://doi.org/10.1136/jmedgenet-2019-106072

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author = "IMM Lakeman and FS Hilbers and M Rodr{\'i}guez-Girondo and A Lee and MPG Vreeswijk and Antoinette Hollestelle and Caroline Seynaeve and H Meijers-Heijboer and JC Oosterwijk and N Hoogerbrugge and E Olah and HFA Vasen and \{van Asperen\}, CJ and P Devilee",

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Lakeman, IMM, Hilbers, FS, Rodríguez-Girondo, M, Lee, A, Vreeswijk, MPG, Hollestelle, A, Seynaeve, C, Meijers-Heijboer, H, Oosterwijk, JC, Hoogerbrugge, N, Olah, E, Vasen, HFA, van Asperen, CJ & Devilee, P 2019, 'Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families', Journal of Medical Genetics, vol. 56, no. 9, pp. 581-589. https://doi.org/10.1136/jmedgenet-2019-106072

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T1 - Addition of a 161-SNP polygenic risk score to family history-based risk prediction: impact on clinical management in non-BRCA1/2 breast cancer families

AU - Lakeman, IMM

AU - Hilbers, FS

AU - Rodríguez-Girondo, M

AU - Lee, A

AU - Vreeswijk, MPG

AU - Hollestelle, Antoinette

AU - Seynaeve, Caroline

AU - Meijers-Heijboer, H

AU - Oosterwijk, JC

AU - Hoogerbrugge, N

AU - Olah, E

AU - Vasen, HFA

AU - van Asperen, CJ

AU - Devilee, P

PY - 2019

Y1 - 2019

U2 - 10.1136/jmedgenet-2019-106072

DO - 10.1136/jmedgenet-2019-106072

M3 - Article

C2 - 31186341

SN - 0022-2593

VL - 56

SP - 581

EP - 589

JO - Journal of Medical Genetics

JF - Journal of Medical Genetics

IS - 9

ER -