Advanced three-dimensional quantitative coronary angiographic assessment of bifurcation lesions: methodology and phantom validation

Chrysafios Girasis, JCH Schuurbiers, Takashi Muramatsu, JP Aben, Yoshinobu Onuma, S Soekhradj, Marie-Angele Morel, Robert Jan van Geuns, Jolanda Wentzel, PWJC (Patrick) Serruys

Research output: Contribution to journalArticleAcademicpeer-review

37 Citations (Scopus)


Aims: Validation of new three-dimensional (3-D) bifurcation quantitative coronary angiography (QCA) software. Methods and results: Cardiovascular Angiography Analysis System (CAAS 5v10) allows 3-D angiographic reconstructions based on two or more 2-D projection images. Measurements for minimal lumen diameter (MLD), reference vessel diameter (RVD), percent diameter stenosis (DS) and bifurcation angle (BA) were validated against precision manufactured phantom bifurcations. Length measurements were validated against angiographic measurement catheters inserted into a plexiglas bifurcation phantom. In 3-D re Conclusions: Advances in the methodology of 3-D reconstruction and quantitative analysis for bifurcation lesions translated into highly accurate, precise and reproducible measures of diameter, length and BA.
Original languageUndefined/Unknown
Pages (from-to)1451-1460
Number of pages10
Issue number12
Publication statusPublished - 2013

Research programs

  • EMC COEUR-09

Cite this