An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

Georgia S. Karanasiou; Panagiota I. Tsompou; Nikolaos Tachos; Gianna E. Karanasiou; Antonis Sakellarios; Savvas Kyriakidis; Luca Antonini; Giancarlo Pennati; Lorenza Petrini; Frank Gijsen; Farhad Rikhtegar Nezami; Rami Tzafriri; Martin Fawdry; Dimitrios I. Fotiadis

doi:10.1109/EMBC46164.2021.9629950

An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

Georgia S. Karanasiou
, Panagiota I. Tsompou
, Nikolaos Tachos
, Gianna E. Karanasiou
, Antonis Sakellarios
, Savvas Kyriakidis
, Luca Antonini
, Giancarlo Pennati
, Lorenza Petrini
, Frank Gijsen
, Farhad Rikhtegar Nezami
, Rami Tzafriri
, Martin Fawdry
, Dimitrios I. Fotiadis

Foundation for Research and Technology-Hellas
University of Ioannina
Polytechnic University of Milan
Erasmus University Rotterdam
Massachusetts Institute of Technology
University of Galway
Boston Scientific Limited

Research output: Contribution to journal › Conference article › Academic › peer-review

3 Citations (Scopus)

Abstract

The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.

Original language	English
Pages (from-to)	4213-4217
Number of pages	5
Journal	Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
DOIs	https://doi.org/10.1109/EMBC46164.2021.9629950
Publication status	Published - 1 Nov 2021
Externally published	Yes
Event	43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021 - Virtual, Online, Mexico Duration: 1 Nov 2021 → 5 Nov 2021

Bibliographical note

Publisher Copyright:
© 2021 IEEE.

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10.1109/EMBC46164.2021.9629950

Cite this

Karanasiou, G. S., Tsompou, P. I., Tachos, N., Karanasiou, G. E., Sakellarios, A., Kyriakidis, S., Antonini, L., Pennati, G., Petrini, L., Gijsen, F., Nezami, F. R., Tzafriri, R., Fawdry, M., & Fotiadis, D. I. (2021). An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 4213-4217. https://doi.org/10.1109/EMBC46164.2021.9629950

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title = "An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation",

abstract = "The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.",

author = "Karanasiou, \{Georgia S.\} and Tsompou, \{Panagiota I.\} and Nikolaos Tachos and Karanasiou, \{Gianna E.\} and Antonis Sakellarios and Savvas Kyriakidis and Luca Antonini and Giancarlo Pennati and Lorenza Petrini and Frank Gijsen and Nezami, \{Farhad Rikhtegar\} and Rami Tzafriri and Martin Fawdry and Fotiadis, \{Dimitrios I.\}",

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doi = "10.1109/EMBC46164.2021.9629950",

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Karanasiou, GS, Tsompou, PI, Tachos, N, Karanasiou, GE, Sakellarios, A, Kyriakidis, S, Antonini, L, Pennati, G, Petrini, L, Gijsen, F, Nezami, FR, Tzafriri, R, Fawdry, M & Fotiadis, DI 2021, 'An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation', Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, pp. 4213-4217. https://doi.org/10.1109/EMBC46164.2021.9629950

An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation. / Karanasiou, Georgia S.; Tsompou, Panagiota I.; Tachos, Nikolaos et al.
In: Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS, 01.11.2021, p. 4213-4217.

Research output: Contribution to journal › Conference article › Academic › peer-review

TY - JOUR

T1 - An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

AU - Karanasiou, Georgia S.

AU - Tsompou, Panagiota I.

AU - Tachos, Nikolaos

AU - Karanasiou, Gianna E.

AU - Sakellarios, Antonis

AU - Kyriakidis, Savvas

AU - Antonini, Luca

AU - Pennati, Giancarlo

AU - Petrini, Lorenza

AU - Gijsen, Frank

AU - Nezami, Farhad Rikhtegar

AU - Tzafriri, Rami

AU - Fawdry, Martin

AU - Fotiadis, Dimitrios I.

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N2 - The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.

AB - The introduction of Bioresorbable Vascular Scaffolds (BVS) has revolutionized the treatment of atherosclerosis. InSilc is an in silico clinical trial (ISCT) platform in a Cloud-based environment used for the design, development and evaluation of BVS. Advanced multi-disciplinary and multiscale models are integrated in the platform towards predicting the short/acute and medium/long term scaffold performance. In this study, InSilc platform is employed in a use case scenario and demonstrates how the whole in silico pipeline allows the interpretation of the effect of the arterial anatomy configuration on stent implantation.

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DO - 10.1109/EMBC46164.2021.9629950

M3 - Conference article

C2 - 34892153

AN - SCOPUS:85122549815

SN - 1557-170X

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EP - 4217

JO - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

JF - Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS

T2 - 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021

Y2 - 1 November 2021 through 5 November 2021

ER -

Karanasiou GS, Tsompou PI, Tachos N, Karanasiou GE, Sakellarios A, Kyriakidis S et al. An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation. Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. 2021 Nov 1;4213-4217. doi: 10.1109/EMBC46164.2021.9629950

An in silico trials platform for the evaluation of effect of the arterial anatomy configuration on stent implantation

Abstract

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