An introduction to health technology assessment and health economic evaluation: an online self-learning course

Isabell Wiethoff*, Silvia M.A.A. Evers, Michelle Michels, Mickaël Hiligsmann

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

1 Citation (Scopus)


Cardiovascular diseases impose an enormous burden on patients and society. New health technologies promise to lower this burden; however, novel treatments often come at a high cost. In the Netherlands, health technology assessment (HTA) is increasingly being used to inform policy bodies about the optimal distribution of scarce healthcare resources and to guide decision-making about financing and reimbursement. In particular, economic evaluations, as one pillar of HTA, are frequently used to compare the costs and effects of different interventions. This paper aims to define HTA and its relevance to healthcare policy as well as providing a comprehensive overview of the methodology of economic evaluations targeting health professionals and researchers with limited prior knowledge of this subject. Accordingly, different types of economic evaluations are introduced, together with their respective costs and outcomes. Further, the results of economic evaluations are explained, along with techniques for performing them and methods for coping with uncertainty. In addition to this paper-based learning format, each chapter is complemented by a video lecture with further information and practical examples, helping to better understand and analyse health economic studies.

Original languageEnglish
Pages (from-to)219-225
Number of pages7
JournalNetherlands Heart Journal
Issue number6
Early online date12 May 2023
Publication statusPublished - 2023

Bibliographical note

Funding Information:
The course was developed for the ‘Double Dose of energy and efforts of the national DOSIS consortium to design and test new diagnostic and treatment strategies for inherited cardiomyopathies (DOUBLE DOSE)’, which was funded by the Dutch Heart Foundation and Stichting Hartedroom (grant number: 2020B005).

Publisher Copyright:
© 2023, The Author(s).


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