An updated Asia Pacific Consensus Recommendations on colorectal cancer screening

JJY Sung, SC Ng, FKL Chan, HM Chiu, HS Kim, T Matsuda, SSM Ng, JYW Lau, S Zheng, S Adler, N Reddy, KG Yeoh, KKF Tsoi, JYL Ching, Ernst Kuipers, L Rabeneck, GP Young, RJ Steele, D Lieberman, KL Goh

Research output: Contribution to journalArticleAcademicpeer-review

321 Citations (Scopus)

Abstract

Objective Since the publication of the first Asia Pacific Consensus on Colorectal Cancer (CRC) in 2008, there are substantial advancements in the science and experience of implementing CRC screening. The Asia Pacific Working Group aimed to provide an updated set of consensus recommendations. Design Members from 14 Asian regions gathered to seek consensus using other national and international guidelines, and recent relevant literature published from 2008 to 2013. A modified Delphi process was adopted to develop the statements. Results Age range for CRC screening is defined as 5075 years. Advancing age, male, family history of CRC, smoking and obesity are confirmed risk factors for CRC and advanced neoplasia. A risk-stratified scoring system is recommended for selecting high-risk patients for colonoscopy. Quantitative faecal immunochemical test (FIT) instead of guaiac-based faecal occult blood test (gFOBT) is preferred for average-risk subjects. Ancillary methods in colonoscopy, with the exception of chromoendoscopy, have not proven to be superior to high-definition white light endoscopy in identifying adenoma. Quality of colonoscopy should be upheld and quality assurance programme should be in place to audit every aspects of CRC screening. Serrated adenoma is recognised as a risk for interval cancer. There is no consensus on the recruitment of trained endoscopy nurses for CRC screening. Conclusions Based on recent data on CRC screening, an updated list of recommendations on CRC screening is prepared. These consensus statements will further enhance the implementation of CRC screening in the Asia Pacific region.
Original languageUndefined/Unknown
Pages (from-to)121-132
Number of pages12
JournalGut
Volume64
Issue number1
DOIs
Publication statusPublished - 2015

Cite this