Anaplasma phagocytophilum from Rodents and Sheep, China

L Zhan, W-C Cao, JF Jiang, XA Zhang, YX (Yun Xi) Liu, XM Wu, WY Zhang, PH Zhang, CL Bian, JS Dumler, H Yang, SQ Zuo, CY Chu, W (Wei) Liu, Jan hendrik Richardus, Dik Habbema

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Abstract

To characterize the strains of Anaplasma phagocytophilum in wild and domestic animals in China, we isolated the organism from rodents and sheep in northeastern China. We isolated 3 strains (2 from rodents and 1 from sick sheep) through propagation in BALB/c mice and then cell culture in HL60 cells. The 3 isolates were identified by Wright-Giemsa staining, immunofluorescence, and electronic microscopy and were characterized by sequence analyses of the 16S rRNA gene, partial citrate synthase gene, major surface protein 4 gene, and heat shock protein gene. The multiple sequences of the 3 isolates were identical to each other but different from all known strains from other countries. The public health and veterinary relevance of the isolates deserves further investigation.
Original languageUndefined/Unknown
Pages (from-to)764-768
Number of pages5
JournalEmerging Infectious Diseases
Volume16
Issue number5
Publication statusPublished - 2010

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