And the fat lady sings about phosphate and calcium

Carsten A. Wagner*, Pedro H. Imenez Silva, Isabel Rubio-Aliaga

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorPopular

9 Citations (Scopus)

Abstract

Adipose tissue has been long recognized as secreting various endocrine factors. Emerging evidence demonstrates that adipokines play a role in modulating systemic mineral homeostasis through endocrine loops involving interleukin-6, leptin, and now also adiponectin, which all interact with FGF23 and vitamin D and thereby change the renal control of calcium and phosphate metabolism. Understanding these regulatory loops may shed light on a complex interorgan crosstalk controlling mineral homeostasis and its dysregulation in diseases associated with obesity.

Original languageEnglish
Pages (from-to)270-272
Number of pages3
JournalKidney International
Volume91
Issue number2
DOIs
Publication statusPublished - Feb 2017
Externally publishedYes

Bibliographical note

Publisher Copyright:
© 2016 International Society of Nephrology

Fingerprint

Dive into the research topics of 'And the fat lady sings about phosphate and calcium'. Together they form a unique fingerprint.

Cite this