And the fat lady sings about phosphate and calcium

Carsten A. Wagner; Pedro H. Imenez Silva; Isabel Rubio-Aliaga

doi:10.1016/j.kint.2016.11.009

And the fat lady sings about phosphate and calcium

Carsten A. Wagner^*, Pedro H. Imenez Silva, Isabel Rubio-Aliaga

^*Corresponding author for this work

University of Zurich

Research output: Contribution to journal › Comment/Letter to the editor › Popular

9 Citations (Scopus)

Abstract

Adipose tissue has been long recognized as secreting various endocrine factors. Emerging evidence demonstrates that adipokines play a role in modulating systemic mineral homeostasis through endocrine loops involving interleukin-6, leptin, and now also adiponectin, which all interact with FGF23 and vitamin D and thereby change the renal control of calcium and phosphate metabolism. Understanding these regulatory loops may shed light on a complex interorgan crosstalk controlling mineral homeostasis and its dysregulation in diseases associated with obesity.

Original language	English
Pages (from-to)	270-272
Number of pages	3
Journal	Kidney International
Volume	91
Issue number	2
DOIs	https://doi.org/10.1016/j.kint.2016.11.009
Publication status	Published - Feb 2017
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2016 International Society of Nephrology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.kint.2016.11.009

Cite this

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AU - Imenez Silva, Pedro H.

AU - Rubio-Aliaga, Isabel

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AB - Adipose tissue has been long recognized as secreting various endocrine factors. Emerging evidence demonstrates that adipokines play a role in modulating systemic mineral homeostasis through endocrine loops involving interleukin-6, leptin, and now also adiponectin, which all interact with FGF23 and vitamin D and thereby change the renal control of calcium and phosphate metabolism. Understanding these regulatory loops may shed light on a complex interorgan crosstalk controlling mineral homeostasis and its dysregulation in diseases associated with obesity.

UR - https://www.scopus.com/pages/publications/85033466450

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DO - 10.1016/j.kint.2016.11.009

M3 - Comment/Letter to the editor

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JO - Kidney International

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And the fat lady sings about phosphate and calcium

Abstract

Bibliographical note

UN SDGs

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