Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia

MH Gasem; H Farida; A Ahmed; Juliette Severin; A Suryanto; B Isbandrio; Henri Verbrugh; RA Hartskeerl; PJ van den Broek

doi:10.1128/JCM.02093-15

Are Pathogenic Leptospira Species Agents of Community-Acquired Pneumonia? Case Reports of Leptospirosis Presenting as Pneumonia

MH Gasem, H Farida, A Ahmed, Juliette Severin, A Suryanto, B Isbandrio, Henri Verbrugh, RA Hartskeerl, PJ van den Broek

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acute-phase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis.

Original language	Undefined/Unknown
Pages (from-to)	197-199
Number of pages	3
Journal	Journal of Clinical Microbiology
Volume	54
Issue number	1
DOIs	https://doi.org/10.1128/JCM.02093-15
Publication status	Published - 2016

Research programs

EMC MM-04-28-01

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10.1128/JCM.02093-15

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Cite this

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abstract = "We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acute-phase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis.",

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AU - Verbrugh, Henri

AU - Hartskeerl, RA

AU - van den Broek, PJ

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AB - We report four Indonesian cases meeting the clinical and radiological criteria for community-acquired pneumonia and other findings suggestive of leptospirosis. Quantitative PCR (qPCR) analyses of serum and urine samples and serology confirmed the diagnosis of leptospirosis in each. Results of qPCR analysis of throat swabs were concordant with those obtained with acute-phase serum samples, which suggests its potential for use as a noninvasive diagnostic tool for leptospirosis.

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