ASO Visual Abstract: Hepatic Arterial Infusion Pump Chemotherapy for Unresectable Intrahepatic Cholangiocarcinoma - A Systematic Review and Meta-analysis

Jessica J. Holster, Marouan El Hassnaoui, Stijn Franssen, Jan N. M. IJzermans, Jeroen de Jonge, Bianca Mostert, Wojciech G. Polak, Roeland F. de Wilde, Marjolein Y. Homs, Bas Groot Koerkamp*

*Corresponding author for this work

Research output: Contribution to journalMeeting AbstractAcademicpeer-review

Abstract

Hepatic arterial infusion pump (HAIP) chemotherapy
with floxuridine has been explored as a means to control cancer
in the liver. In this systematic review (https://doi.org/10.1245/
s10434-022-11439-x), 478 patients with unresectable intrahepatic cholangiocarcinoma (iCCA) were identified from nine
studies; survival outcomes of 154 patients were used in the
meta-analysis. HAIP chemotherapy with floxuridine for
patients with unresectable iCCA was associated with a pooled
3-year overall survival (OS) of 39.5% (95% confidence interval
(CI) 31.5–47.4%) and a weighted median OS of 29.0 months
(range 25.0–39 months).
Original languageEnglish
Pages (from-to)5541-5542
Number of pages2
JournalAnnals of Surgical Oncology
Volume29
Issue number9
Early online dateMar 2022
DOIs
Publication statusPublished - Sept 2022

Bibliographical note

© Society of Surgical Oncology 2022

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