Assessing the quality of life of people with chronic wounds by using the cross-culturally valid and revised Wound-QoL questionnaire

Catharina C. von Stülpnagel*, Neuza da Silva, Matthias Augustin, Bibi van Montfrans, Caroline Fife, Ann Mari Fagerdahl, Alexander Gamus, Toni M. Klein, Christine Blome, Rachel Sommer

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

10 Citations (Scopus)
103 Downloads (Pure)


The Wound-QoL is an often used reliable and valid measure, originally developed in Germany. It has been sequentially translated and validated for other languages/countries, for the measurement of health-related quality of life (HRQoL) in patients with chronic wounds. However, a study from the United States postulated its benefits from further adaptations. Furthermore, some patients struggled to provide an answer for some of the items. We aimed to test the cross-cultural structure and psychometric performance of the questionnaire to suggest necessary revisions. This cross-sectional analysis of existing data sets included 1185 patients from Germany, the US, the Netherlands, Spain, Sweden, and Israel. Patients in the U.S. Wound Registry completed the Wound-QoL during routine care. Different studies comprised the data collection in the other countries. Almost half of the patients were women (48.4%). Furthermore, 42.6% were diagnosed with leg ulcers. Their average age was 66 years. We used a confirmatory factor analysis and an unconstrained graded response model. We revised and shortened the Wound-QoL from 17 to 14 items. In addition, we supported the cross-cultural metric invariance of the revised Wound-QoL questionnaire. The new version with 14 items and three dimensions revealed good psychometric properties with Cronbach's alpha (α) of 0.913 for the total score, and 0.709–0.907 for different dimensions. Furthermore, we provided strict invariance for different clinical variables. In conclusion, the revised Wound-QoL is a reliable and cross-cultural instrument to measure the HRQoL on patients with chronic wounds. Future studies should analyse the revised Wound-QoL for convergent validity with generic HRQoL questionnaires as well as for determining its sensitivity to clinical change.

Original languageEnglish
Pages (from-to)452-459
Number of pages8
JournalWound Repair and Regeneration
Issue number3
Publication statusPublished - 1 May 2021

Bibliographical note

The authors would like to thank Elena Conde Montero for collecting and providing the data from Spain. The authors would also like to thank the Scientific Communication Team of the IVDP, in particular Mathilda Meyer and Mario Gehoff, for copy editing. Open Access funding enabled and organized by Projekt DEAL.

Publisher Copyright:
© 2021 The Authors. Wound Repair and Regeneration published by Wiley Periodicals LLC on behalf of The Wound Healing Society.


Dive into the research topics of 'Assessing the quality of life of people with chronic wounds by using the cross-culturally valid and revised Wound-QoL questionnaire'. Together they form a unique fingerprint.

Cite this