TY - JOUR
T1 - Assessment Methods and Prevalence of Cognitive Dysfunction in Patients with Low-grade Glioma
T2 - A Systematic Review
AU - van Loon, Ellen M. P.
AU - Heijenbrok-Kal, Majanka H.
AU - van Loon, Wouter S.
AU - van den Bent, Martin J.
AU - Vincent, Arnaud J. P. E.
AU - de Koning, Inge
AU - Ribbers, Gerard M.
PY - 2015/6
Y1 - 2015/6
N2 - Objective: To systematically review the literature for studies on cognitive functioning in patients with low-grade glioma to evaluate assessment methods and prevalence of cognitive dysfunction.Data sources: A search was made in PubMed, Embase, and PsycINFO for articles published between January 2002 and June 2012 using cognition, memory, attention, executive functioning, and low-grade glioma as search terms.Study selection: Two reviewers independently performed the study selection and data extraction. Inclusion criteria were: studies including at least 10 adult patients, with suspected or confirmed low-grade glioma and cognitive functioning as outcome measure.Data extraction: A standard data extraction form was used, with items regarding study quality, patient characteristics, type of measurement instruments, cognitive domain, definition of cognitive dysfunction, and reported prevalence.Data synthesis: Of the 312 articles screened on title/abstract, 69 were screened on full-text and, finally, 17 were included. A total of 46 different measurement instruments were found for the assessment of cognitive functioning; 5 of these were used 5 or more times. There was variability in the definition of cognitive dysfunction. The reported prevalence of cognitive dysfunction ranged from 19% to 83%.Conclusion: Many patients with low-grade glioma experience cognitive dysfunction. However, there is no consensus on how to assess cognitive functioning in these patients.
AB - Objective: To systematically review the literature for studies on cognitive functioning in patients with low-grade glioma to evaluate assessment methods and prevalence of cognitive dysfunction.Data sources: A search was made in PubMed, Embase, and PsycINFO for articles published between January 2002 and June 2012 using cognition, memory, attention, executive functioning, and low-grade glioma as search terms.Study selection: Two reviewers independently performed the study selection and data extraction. Inclusion criteria were: studies including at least 10 adult patients, with suspected or confirmed low-grade glioma and cognitive functioning as outcome measure.Data extraction: A standard data extraction form was used, with items regarding study quality, patient characteristics, type of measurement instruments, cognitive domain, definition of cognitive dysfunction, and reported prevalence.Data synthesis: Of the 312 articles screened on title/abstract, 69 were screened on full-text and, finally, 17 were included. A total of 46 different measurement instruments were found for the assessment of cognitive functioning; 5 of these were used 5 or more times. There was variability in the definition of cognitive dysfunction. The reported prevalence of cognitive dysfunction ranged from 19% to 83%.Conclusion: Many patients with low-grade glioma experience cognitive dysfunction. However, there is no consensus on how to assess cognitive functioning in these patients.
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=eur_pure&SrcAuth=WosAPI&KeyUT=WOS:000356318300001&DestLinkType=FullRecord&DestApp=WOS
U2 - 10.2340/16501977-1975
DO - 10.2340/16501977-1975
M3 - Article
C2 - 25994416
SN - 1650-1977
VL - 47
SP - 481
EP - 488
JO - Journal of Rehabilitation Medicine
JF - Journal of Rehabilitation Medicine
IS - 6
ER -