Association between obesity and postoperative atrial fibrillation in patients undergoing cardiac operations: A systematic review and meta-analysis

Adrian V. Hernandez*, Cardiovascular Meta-Analysis Research Group, Roop Kaw, Vinay Pasupuleti, Pouya Bina, John P.A. Ioannidis, Hector Bueno, Eric Boersma, Marc Gillinov

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

55 Citations (Scopus)

Abstract

In a systematic review and random-effects meta-analysis, we evaluated whether obesity is associated with postoperative atrial fibrillation (POAF) in patients undergoing cardiac operations. We selected 18 observational studies until December 2011 that excluded patients with preoperative AF (n = 36,147). Obese patients had a modest higher risk of POAF compared with nonobese (odds ratio, 1.12; 95% confidence interval, 1.04 to 1.21; p = 0.002). The association between obesity and POAF did not vary substantially by type of cardiac operation, study design, or year of publication. POAF was significantly associated with a higher risk of stroke, respiratory failure, and operative death.

Original languageEnglish
Pages (from-to)1104-1116
Number of pages13
JournalAnnals of Thoracic Surgery
Volume96
Issue number3
Early online date12 Aug 2013
DOIs
Publication statusPublished - Sept 2013

Bibliographical note

© 2013 by The Society of Thoracic Surgeons

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