Association between spinal morning stiffness and lumbar disc degeneration: the Rotterdam Study

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Abstract

Objective: To explore the associations between spinal morning stiffness and lumbar disc degeneration (LDD). Design: Data from a cross-sectional general population-based study (Rotterdam Study-I) were used. Intervertebral disc spaces and osteophytes of people aged >= 55 years were scored on lumbar lateral radiographs (L1-2 through L5-S1 was scored). Logistic regression analysis was used to explore associations between spinal morning stiffness and two definitions of LDD (i.e., 'narrowing' and 'osteophytes'). Spinal morning stiffness combined with low back pain and its association with LDD was also analy Results: Lumbar lateral radiographs were scored for 2,819 participants. Both definitions of LDD were associated with spinal morning stiffness: adjusted odds ratio (aOR) 1.3; 95% confidence interval (CI): 1.1-1.6 for 'osteophytes' and aOR 1.8; 95% CI: 1.4-2.2 for 'narrowing'. Both the odds ratios increased when spinal morning stiffness was combined with low back pain: aOR 1.5; 95% CI: 1.1-2.0 for 'osteophytes' and aOR 2.5; 95% CI: 1.9-3.4 for 'narrowing'. When morning stiffness in the legs was co Conclusions: Reported spinal morning stiffness is associated with LDD. The associations increased when we combined spinal morning stiffness with low back pain. The magnitude of the association for the definition 'narrowing' is similar to the association between morning stiffness in the legs and knee or hip OA. (c) 2012 Osteoarthritis Research Society International. Published by Elsevier Ltd. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)982-987
Number of pages6
JournalOsteoarthritis and Cartilage
Volume20
Issue number9
DOIs
Publication statusPublished - 2012

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