TY - JOUR
T1 - Association of different obesity indices with nephrolithiasis in community-dwelling older adults
AU - Gholizade, Mohamad
AU - Marzban, Maryam
AU - Farhadi, Akram
AU - Tangestani, Hadith
AU - Mahmudpour, Mehdi
AU - Trajanoska, Katerina
AU - Shabankari, Elnaz
AU - Rezaie, Sadaf
AU - Khaleghi, Mohammad Mehdi
AU - Amini, Azam
AU - Nabipour, Iraj
AU - Kalantarhormozi, Mohammadreza
AU - Emamat, Hadi
AU - Ostovar, Afshin
AU - Larijani, Bagher
AU - Darabi, Amir Hossein
N1 - Publisher Copyright:
© 2024 Asia Oceania Association for the Study of Obesity
PY - 2024/9
Y1 - 2024/9
N2 - Background and objective: Obesity has been linked to various conditions, including nephrolithiasis. Given the rising prevalence of both nephrolithiasis and obesity in older adults, this study aimed to examine the association of different obesity-related indices with nephrolithiasis. Methods: This cross-sectional study included 2419 individuals (mean age 69.34 ± 6.40; 51.92 % female) from the Bushehr Elderly Health (BEH) program, a population-based measured using Dual-energy X-ray absorptiometry (DXA), while nephrolithiasis history was assessed through medical records. The associations between obesity-related indices and nephrolithiasis were analyzed using multivariable logistic regression models, adjusted for relevant confounders. Results: Among the 2419 participants, 212 (8.76 %) had a history of nephrolithiasis. In the overall population, only the android-to-gynoid fat mass (FM) ratio was significantly associated with nephrolithiasis (odds ratio [OR] 3.28, 95 % Confidence Interval [CI] 1.06–10.18). In females, the trunk-to-limb FM ratio (OR 2.62, 95 % CI 1.10–6.23) and the visceral adipose index (VAI) (OR 1.092, 95 % CI 1.005–1.187) were associated with nephrolithiasis. In males, only the body adipose index (BAI) was significantly associated with nephrolithiasis (OR 1.082, 95 % CI 1.017–1.151). Conclusion: In this study, the android-to-gynoid FM ratio in the total population, the trunk-to-limb FM ratio and VAI in females, and BAI in males were significantly associated with nephrolithiasis. Monitoring and managing these indices may enhance quality of life for elderly individuals by facilitating early diagnosis of nephrolithiasis and preventing stone formation.
AB - Background and objective: Obesity has been linked to various conditions, including nephrolithiasis. Given the rising prevalence of both nephrolithiasis and obesity in older adults, this study aimed to examine the association of different obesity-related indices with nephrolithiasis. Methods: This cross-sectional study included 2419 individuals (mean age 69.34 ± 6.40; 51.92 % female) from the Bushehr Elderly Health (BEH) program, a population-based measured using Dual-energy X-ray absorptiometry (DXA), while nephrolithiasis history was assessed through medical records. The associations between obesity-related indices and nephrolithiasis were analyzed using multivariable logistic regression models, adjusted for relevant confounders. Results: Among the 2419 participants, 212 (8.76 %) had a history of nephrolithiasis. In the overall population, only the android-to-gynoid fat mass (FM) ratio was significantly associated with nephrolithiasis (odds ratio [OR] 3.28, 95 % Confidence Interval [CI] 1.06–10.18). In females, the trunk-to-limb FM ratio (OR 2.62, 95 % CI 1.10–6.23) and the visceral adipose index (VAI) (OR 1.092, 95 % CI 1.005–1.187) were associated with nephrolithiasis. In males, only the body adipose index (BAI) was significantly associated with nephrolithiasis (OR 1.082, 95 % CI 1.017–1.151). Conclusion: In this study, the android-to-gynoid FM ratio in the total population, the trunk-to-limb FM ratio and VAI in females, and BAI in males were significantly associated with nephrolithiasis. Monitoring and managing these indices may enhance quality of life for elderly individuals by facilitating early diagnosis of nephrolithiasis and preventing stone formation.
UR - http://www.scopus.com/inward/record.url?scp=85210539186&partnerID=8YFLogxK
U2 - 10.1016/j.orcp.2024.11.003
DO - 10.1016/j.orcp.2024.11.003
M3 - Article
C2 - 39616123
AN - SCOPUS:85210539186
SN - 1871-403X
VL - 18
SP - 371
EP - 379
JO - Obesity Research and Clinical Practice
JF - Obesity Research and Clinical Practice
IS - 5
ER -
