TY - JOUR
T1 - Associations between Recreational Screen Time and Brain Health in Middle-Aged and Older Adults
T2 - A Large Prospective Cohort Study
AU - Xu, Chenjie
AU - Cao, Zhi
AU - Lu, Zuolin
AU - Hou, Yabing
AU - Wang, Yaogang
AU - Zhang, Xinyu
N1 - Publisher Copyright:
© 2024 AMDA – The Society for Post-Acute and Long-Term Care Medicine
PY - 2024/8
Y1 - 2024/8
N2 - Objectives: To investigate the associations of recreational screen time with risks of brain-related disorders (dementia, stroke, and Parkinson's disease) and neuroimaging features. Design: Prospective cohort study. Setting and Participants: A total of 407,792 participants from the UK Biobank who were free of dementia, stroke, or Parkinson's disease at enrollment (2006–2010). Methods: TV viewing and time spent using the computer were self-reported at baseline. Among a subsample of 40,692 participants, neuroimaging features were measured by magnetic resonance imaging in 2014. Data were analyzed using Cox proportional hazard models, restricted cubic spline models, and general linear regression models. Results: During a median follow-up of 12.6 years, 5227 incident dementia, 6822 stroke, and 2308 Parkinson's disease cases were identified. Compared with TV viewing >0–1 h/day, watching TV ≥5 h/day was associated with higher risks of dementia [hazard ratio (HR), 1.44; 95% confidence interval (CI), 1.28–1.62], stroke (HR, 1.12; 95% CI, 1.01–1.25), and Parkinson's disease (HR, 1.28; 95% CI, 1.06–1.54). Moreover, we observed inverse associations between TV viewing time and both gray matter volume and hippocampus volume (Ptrend <.001). However, we did not observe the significant associations between discretional computer use and brain-related disorders or neuroimaging features. Conclusions and Implications: Our findings suggest that high TV viewing time is associated with increased risk of various brain-related disorders, highlighting recreational TV viewing could have an important impact on brain-related health.
AB - Objectives: To investigate the associations of recreational screen time with risks of brain-related disorders (dementia, stroke, and Parkinson's disease) and neuroimaging features. Design: Prospective cohort study. Setting and Participants: A total of 407,792 participants from the UK Biobank who were free of dementia, stroke, or Parkinson's disease at enrollment (2006–2010). Methods: TV viewing and time spent using the computer were self-reported at baseline. Among a subsample of 40,692 participants, neuroimaging features were measured by magnetic resonance imaging in 2014. Data were analyzed using Cox proportional hazard models, restricted cubic spline models, and general linear regression models. Results: During a median follow-up of 12.6 years, 5227 incident dementia, 6822 stroke, and 2308 Parkinson's disease cases were identified. Compared with TV viewing >0–1 h/day, watching TV ≥5 h/day was associated with higher risks of dementia [hazard ratio (HR), 1.44; 95% confidence interval (CI), 1.28–1.62], stroke (HR, 1.12; 95% CI, 1.01–1.25), and Parkinson's disease (HR, 1.28; 95% CI, 1.06–1.54). Moreover, we observed inverse associations between TV viewing time and both gray matter volume and hippocampus volume (Ptrend <.001). However, we did not observe the significant associations between discretional computer use and brain-related disorders or neuroimaging features. Conclusions and Implications: Our findings suggest that high TV viewing time is associated with increased risk of various brain-related disorders, highlighting recreational TV viewing could have an important impact on brain-related health.
UR - http://www.scopus.com/inward/record.url?scp=85192098651&partnerID=8YFLogxK
U2 - 10.1016/j.jamda.2024.03.010
DO - 10.1016/j.jamda.2024.03.010
M3 - Article
C2 - 38642587
AN - SCOPUS:85192098651
SN - 1525-8610
VL - 25
JO - Journal of the American Medical Directors Association
JF - Journal of the American Medical Directors Association
IS - 8
M1 - 104990
ER -
