Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology

HJ Wenzel; KD Murray; Saif Haify; MR Hunsaker; JJ Schwartzer; K Kim; AR La Spada; BL Sopher; PJ Hagerman; C Raske; Lies-anne Severijnen; Rob Willemsen; Renate Hukema; RF Berman

doi:10.1186/s40478-019-0677-7

Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology

HJ Wenzel, KD Murray, Saif Haify, MR Hunsaker, JJ Schwartzer, K Kim, AR La Spada, BL Sopher, PJ Hagerman, C Raske, Lies-anne Severijnen, Rob Willemsen, Renate Hukema, RF Berman

Clinical Genetics

Research output: Contribution to journal › Article › Academic › peer-review

13 Citations (Scopus)

13 Downloads (Pure)

Original language	Undefined/Unknown
Article number	27
Journal	Acta neuropathologica communications (online)
Volume	7
DOIs	https://doi.org/10.1186/s40478-019-0677-7
Publication status	Published - 2019

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EMC OR-01

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10.1186/s40478-019-0677-7

Repub_115514_O-A.pdfFinal published version, 14.2 MB

http://hdl.handle.net/1765/115514

Cite this

Wenzel, HJ., Murray, KD., Haify, S., Hunsaker, MR., Schwartzer, JJ., Kim, K., La Spada, AR., Sopher, BL., Hagerman, PJ., Raske, C., Severijnen, L., Willemsen, R., Hukema, R., & Berman, RF. (2019). Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology. Acta neuropathologica communications (online), 7, Article 27. https://doi.org/10.1186/s40478-019-0677-7

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author = "HJ Wenzel and KD Murray and Saif Haify and MR Hunsaker and JJ Schwartzer and K Kim and {La Spada}, AR and BL Sopher and PJ Hagerman and C Raske and Lies-anne Severijnen and Rob Willemsen and Renate Hukema and RF Berman",

year = "2019",

doi = "10.1186/s40478-019-0677-7",

language = "Undefined/Unknown",

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journal = "Acta neuropathologica communications (online)",

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Wenzel, HJ, Murray, KD, Haify, S, Hunsaker, MR, Schwartzer, JJ, Kim, K, La Spada, AR, Sopher, BL, Hagerman, PJ, Raske, C, Severijnen, L, Willemsen, R, Hukema, R & Berman, RF 2019, 'Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology', Acta neuropathologica communications (online), vol. 7, 27. https://doi.org/10.1186/s40478-019-0677-7

Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology. / Wenzel, HJ; Murray, KD; Haify, Saif et al.
In: Acta neuropathologica communications (online), Vol. 7, 27, 2019.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Astroglial-targeted expression of the fragile X CGG repeat premutation in mice yields RAN translation, motor deficits and possible evidence for cell-to-cell propagation of FXTAS pathology

AU - Wenzel, HJ

AU - Murray, KD

AU - Haify, Saif

AU - Hunsaker, MR

AU - Schwartzer, JJ

AU - Kim, K

AU - La Spada, AR

AU - Sopher, BL

AU - Hagerman, PJ

AU - Raske, C

AU - Severijnen, Lies-anne

AU - Willemsen, Rob

AU - Hukema, Renate

AU - Berman, RF

PY - 2019

Y1 - 2019

U2 - 10.1186/s40478-019-0677-7

DO - 10.1186/s40478-019-0677-7

M3 - Article

C2 - 30808398

SN - 2051-5960

VL - 7

JO - Acta neuropathologica communications (online)

JF - Acta neuropathologica communications (online)

M1 - 27

ER -