Bacterial proteases: targets for diagnostics and therapy

Wendy Kaman; John Hays; Hubert Endtz; FJ Bikker

doi:10.1007/s10096-014-2075-1

Bacterial proteases: targets for diagnostics and therapy

Wendy Kaman, John Hays, Hubert Endtz, FJ Bikker

Medical Microbiology & Infectious Diseases

Research output: Contribution to journal › Article › Academic › peer-review

34 Citations (Scopus)

Abstract

Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.

Original language	Undefined/Unknown
Pages (from-to)	1081-1087
Number of pages	7
Journal	European Journal of Clinical Microbiology & Infectious Diseases
Volume	33
Issue number	7
DOIs	https://doi.org/10.1007/s10096-014-2075-1
Publication status	Published - 2014

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Access to Document

10.1007/s10096-014-2075-1

http://hdl.handle.net/1765/56072

Cite this

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AB - Proteases are essential for the proliferation and growth of bacteria, and are also known to contribute to bacterial virulence. This makes them interesting candidates as diagnostic and therapeutic targets for infectious diseases. In this review, the authors discuss the most recent developments and potential applications for bacterial proteases in the diagnosis and treatment of bacterial infections. Current and future bacterial protease targets are described and their limitations outlined.

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DO - 10.1007/s10096-014-2075-1

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