Barkhof Magnetic Resonance Imaging Criteria Predict Early Relapse in Pediatric Multiple Sclerosis

Rinze Neuteboom; Immy Ketelslegers; Martijn Boon; Coriene Catsman - Berrevoets; Rogier Hintzen

doi:10.1016/j.pediatrneurol.2009.07.013

Barkhof Magnetic Resonance Imaging Criteria Predict Early Relapse in Pediatric Multiple Sclerosis

Rinze Neuteboom, Immy Ketelslegers, Martijn Boon, Coriene Catsman - Berrevoets, Rogier Hintzen

Research output: Contribution to journal › Article › Academic › peer-review

10 Citations (Scopus)

Abstract

We sought to identify clinical and radiologic features predicting early relapse after a diagnosis of multiple sclerosis in children. In this nationwide retrospective multicenter study in The Netherlands, we included 28 children with multiple sclerosis with onset before age 16 years. Magnetic resonance images and clinical features at the onset of disease were evaluated. The mean follow-up time was 55 months. Twenty children (71%) had a relapse during follow-up. We found that the presence of at least three of four Barkhof magnetic resonance imaging criteria at the onset of multiple sclerosis signs is predictive of early relapse after a diagnosis of multiple sclerosis in children (P < 0.05). (C) 2010 by Elsevier Inc. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	53-55
Number of pages	3
Journal	Pediatric Neurology
Volume	42
Issue number	1
DOIs	https://doi.org/10.1016/j.pediatrneurol.2009.07.013
Publication status	Published - 2010

Access to Document

10.1016/j.pediatrneurol.2009.07.013

http://hdl.handle.net/1765/28077

Cite this

@article{33577c6107f948b39fcf00572f53f068,

title = "Barkhof Magnetic Resonance Imaging Criteria Predict Early Relapse in Pediatric Multiple Sclerosis",

abstract = "We sought to identify clinical and radiologic features predicting early relapse after a diagnosis of multiple sclerosis in children. In this nationwide retrospective multicenter study in The Netherlands, we included 28 children with multiple sclerosis with onset before age 16 years. Magnetic resonance images and clinical features at the onset of disease were evaluated. The mean follow-up time was 55 months. Twenty children (71%) had a relapse during follow-up. We found that the presence of at least three of four Barkhof magnetic resonance imaging criteria at the onset of multiple sclerosis signs is predictive of early relapse after a diagnosis of multiple sclerosis in children (P < 0.05). (C) 2010 by Elsevier Inc. All rights reserved.",

author = "Rinze Neuteboom and Immy Ketelslegers and Martijn Boon and {Catsman - Berrevoets}, Coriene and Rogier Hintzen",

year = "2010",

doi = "10.1016/j.pediatrneurol.2009.07.013",

language = "Undefined/Unknown",

volume = "42",

pages = "53--55",

journal = "Pediatric Neurology",

issn = "0887-8994",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Barkhof Magnetic Resonance Imaging Criteria Predict Early Relapse in Pediatric Multiple Sclerosis

AU - Neuteboom, Rinze

AU - Ketelslegers, Immy

AU - Boon, Martijn

AU - Catsman - Berrevoets, Coriene

AU - Hintzen, Rogier

PY - 2010

Y1 - 2010

N2 - We sought to identify clinical and radiologic features predicting early relapse after a diagnosis of multiple sclerosis in children. In this nationwide retrospective multicenter study in The Netherlands, we included 28 children with multiple sclerosis with onset before age 16 years. Magnetic resonance images and clinical features at the onset of disease were evaluated. The mean follow-up time was 55 months. Twenty children (71%) had a relapse during follow-up. We found that the presence of at least three of four Barkhof magnetic resonance imaging criteria at the onset of multiple sclerosis signs is predictive of early relapse after a diagnosis of multiple sclerosis in children (P < 0.05). (C) 2010 by Elsevier Inc. All rights reserved.

AB - We sought to identify clinical and radiologic features predicting early relapse after a diagnosis of multiple sclerosis in children. In this nationwide retrospective multicenter study in The Netherlands, we included 28 children with multiple sclerosis with onset before age 16 years. Magnetic resonance images and clinical features at the onset of disease were evaluated. The mean follow-up time was 55 months. Twenty children (71%) had a relapse during follow-up. We found that the presence of at least three of four Barkhof magnetic resonance imaging criteria at the onset of multiple sclerosis signs is predictive of early relapse after a diagnosis of multiple sclerosis in children (P < 0.05). (C) 2010 by Elsevier Inc. All rights reserved.

U2 - 10.1016/j.pediatrneurol.2009.07.013

DO - 10.1016/j.pediatrneurol.2009.07.013

M3 - Article

SN - 0887-8994

VL - 42

SP - 53

EP - 55

JO - Pediatric Neurology

JF - Pediatric Neurology

IS - 1

ER -