Breast Cancer Leptomeningeal Metastasis: The Results of Combined Treatment and the Comparison of Methotrexate and Liposomal Cytarabine As Intra-Cerebrospinal Fluid Chemotherapy

A Niwinska; H Rudnicka; Magdalena Murawska

doi:10.1016/j.clbc.2014.07.004

Breast Cancer Leptomeningeal Metastasis: The Results of Combined Treatment and the Comparison of Methotrexate and Liposomal Cytarabine As Intra-Cerebrospinal Fluid Chemotherapy

A Niwinska, H Rudnicka, Magdalena Murawska

Epidemiology

Research output: Contribution to journal › Article › Academic

55 Citations (Scopus)

Abstract

The aim of this study was to assess the outcome of 149 patients with breast cancer and leptonieningeal metastasis (LM) and to compare the efficacy of intrathecal methotrexate and liposomal cytarabine. Among treatment methods, only systemic therapy prolonged survival in these patients. Survival of patients treated intrathecally with methotrexate and those treated with liposomal cytarabine was comparable.

Original language	Undefined/Unknown
Pages (from-to)	66-72
Number of pages	7
Journal	Clinical Breast Cancer
Volume	15
Issue number	1
DOIs	https://doi.org/10.1016/j.clbc.2014.07.004
Publication status	Published - 2015

Research programs

EMC NIHES-01-66-01

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.clbc.2014.07.004

Cite this

@article{cb0720eb2b9c4be9b1311b832868435f,

title = "Breast Cancer Leptomeningeal Metastasis: The Results of Combined Treatment and the Comparison of Methotrexate and Liposomal Cytarabine As Intra-Cerebrospinal Fluid Chemotherapy",

abstract = "The aim of this study was to assess the outcome of 149 patients with breast cancer and leptonieningeal metastasis (LM) and to compare the efficacy of intrathecal methotrexate and liposomal cytarabine. Among treatment methods, only systemic therapy prolonged survival in these patients. Survival of patients treated intrathecally with methotrexate and those treated with liposomal cytarabine was comparable.",

author = "A Niwinska and H Rudnicka and Magdalena Murawska",

year = "2015",

doi = "10.1016/j.clbc.2014.07.004",

language = "Undefined/Unknown",

volume = "15",

pages = "66--72",

journal = "Clinical Breast Cancer",

issn = "1526-8209",

publisher = "Elsevier Inc.",

number = "1",

}

TY - JOUR

T1 - Breast Cancer Leptomeningeal Metastasis: The Results of Combined Treatment and the Comparison of Methotrexate and Liposomal Cytarabine As Intra-Cerebrospinal Fluid Chemotherapy

AU - Niwinska, A

AU - Rudnicka, H

AU - Murawska, Magdalena

PY - 2015

Y1 - 2015

N2 - The aim of this study was to assess the outcome of 149 patients with breast cancer and leptonieningeal metastasis (LM) and to compare the efficacy of intrathecal methotrexate and liposomal cytarabine. Among treatment methods, only systemic therapy prolonged survival in these patients. Survival of patients treated intrathecally with methotrexate and those treated with liposomal cytarabine was comparable.

AB - The aim of this study was to assess the outcome of 149 patients with breast cancer and leptonieningeal metastasis (LM) and to compare the efficacy of intrathecal methotrexate and liposomal cytarabine. Among treatment methods, only systemic therapy prolonged survival in these patients. Survival of patients treated intrathecally with methotrexate and those treated with liposomal cytarabine was comparable.

U2 - 10.1016/j.clbc.2014.07.004

DO - 10.1016/j.clbc.2014.07.004

M3 - Article

C2 - 25287959

SN - 1526-8209

VL - 15

SP - 66

EP - 72

JO - Clinical Breast Cancer

JF - Clinical Breast Cancer

IS - 1

ER -